ADHDgene Database

Gene Report

Basic Info

Approved Symbol	FEZ1
Approved Name	fasciculation and elongation protein zeta 1 (zygin I)
Location	11q24.2
Position	chr11:125315646-125366213, -
External Links	HGNC: 3659 Entrez Gene: 9638 Ensembl: ENSG00000149557 UCSC: uc001qbx.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)

Gene related GO terms (count: 19)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0045666	positive regulation of neuron differentiation	Biological Process		13
GO:0043015	gamma-tubulin binding	Molecular Function		5
GO:0051654	establishment of mitochondrion localization	Biological Process		1
GO:0047485	protein N-terminus binding	Molecular Function		23
GO:0071363	cellular response to growth factor stimulus	Biological Process		6
GO:0007155	cell adhesion	Biological Process	TAS[9096408]	86
GO:0006810	transport	Biological Process		62
GO:0007411	axon guidance	Biological Process	TAS[9096408]	65
GO:0007399	nervous system development	Biological Process	TAS[9096408]	54
GO:0015630	microtubule cytoskeleton	Cellular Component		34
GO:0010976	positive regulation of neuron projection development	Biological Process		9
GO:0030425	dendrite	Cellular Component		46
GO:0030424	axon	Cellular Component		35
GO:0005886	plasma membrane	Cellular Component		772
GO:0005874	microtubule	Cellular Component		52
GO:0005813	centrosome	Cellular Component		71
GO:0005737	cytoplasm	Cellular Component		690
GO:0005515	protein binding	Molecular Function	IPI[16169070]	910
GO:0005080	protein kinase C binding	Molecular Function		9

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with FEZ1 (count: 12)

Gene Symbol	Pathway Count	Pathway List
KATNB1	7	microtubule cytoskeleton; positive regulation of neuron projection development; axon; plasma membrane; microtubule; centrosome; cytoplasm;
CEP57	6	gamma-tubulin binding; microtubule cytoskeleton; microtubule; centrosome; cytoplasm; protein binding;
SLC6A3	6	protein N-terminus binding; transport; axon; plasma membrane; cytoplasm; protein binding;
ACHE	6	cell adhesion; nervous system development; dendrite; axon; plasma membrane; protein binding;
PAK1	6	axon guidance; dendrite; axon; plasma membrane; cytoplasm; protein binding;
TUBB3	6	axon guidance; microtubule cytoskeleton; axon; plasma membrane; microtubule; cytoplasm;
MARK4	5	gamma-tubulin binding; nervous system development; microtubule cytoskeleton; centrosome; protein binding;
SNCA	5	protein N-terminus binding; axon; plasma membrane; cytoplasm; protein binding;
APC	5	cell adhesion; plasma membrane; centrosome; cytoplasm; protein binding;
CLASP2	5	axon guidance; plasma membrane; microtubule; cytoplasm; protein binding;
GSK3B	5	axon guidance; plasma membrane; centrosome; cytoplasm; protein binding;
PDE2A	5	dendrite; axon; plasma membrane; cytoplasm; protein binding;

Genes shared at least 2 KEGG pathways with FEZ1 (count: 0)

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Region: chr11:125315646..125366213 View in gBrowse