ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0030424
Name axon
Type cellular component
No. of Genes in ADHDgene  37
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 37)

Literature-origin genes (count: 11)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
CNTN4 contactin 4 3p26.3 1(1/0/0) NAS[14571131]
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 3p25.3 1(0/1/0) IEA
CTNNA2 catenin (cadherin-associated protein), alpha 2 2p12-p11.1 2(1/1/0) ISS
DRD2 dopamine receptor D2 11q22-q23 10(3/7/0) ISS
SNCA synuclein, alpha (non A4 component of amyloid precursor) 4q21.3-q22 1(0/1/0) IDA[12958153]
GRM7 glutamate receptor, metabotropic 7 3p26-p25 3(2/1/0) ISS
SLC38A1 solute carrier family 38, member 1 12q13.11 1(0/1/0) IEA
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 5p15.3 70(43/26/1) IDA[12958153]
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 7p12.1 6(5/1/0) IEA
CADM2 cell adhesion molecule 2 3p12.2 1(1/0/0) IEA
HCN1 hyperpolarization activated cyclic nucleotide-gated potassium channel 1 5p12 1(0/1/0) IEA

Genes from other sources Help (count: 26)

Approved Symbol Approved Name Source Evidence[PMID]
LLGL1 lethal giant larvae homolog 1 (Drosophila) Mapped by significant region ISS
BACE1 beta-site APP-cleaving enzyme 1 Mapped by significant region IEA
KATNB1 katanin p80 (WD repeat containing) subunit B 1 Mapped by PBA pathway IEA
CNTNAP2 contactin associated protein-like 2 Mapped by CNV ISS
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 Mapped by LD-proxy IEA
CADM1 cell adhesion molecule 1 Mapped by significant region IEA
KIRREL3 kin of IRRE like 3 (Drosophila) Mapped by significant region IEA
IRX3 iroquois homeobox 3 Mapped by CNV IEA
OMP olfactory marker protein Mapped by significant region IEA
PDE2A phosphodiesterase 2A, cGMP-stimulated Mapped by significant region IEA
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) Mapped by significant region IEA
CANX calnexin Mapped by CNV IEA
TUBB3 tubulin, beta 3 class III Mapped by significant region IEA
ACHE acetylcholinesterase (Yt blood group) Mapped by PBA pathway IBA
EPHA5 EPH receptor A5 Mapped by CNV; Mapped by significant region IEA
FAM168B family with sequence similarity 168, member B Mapped by CNV; Mapped by significant region IEA
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila) Mapped by significant region IEA
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 Mapped by significant region ISS
IGHMBP2 immunoglobulin mu binding protein 2 Mapped by CNV; Mapped by significant region ISS
FKBP15 FK506 binding protein 15, 133kDa Mapped by significant region IEA
NCAM1 neural cell adhesion molecule 1 Mapped by significant region IEA
MTMR2 myotubularin related protein 2 Mapped by significant region ISS
TXN thioredoxin Mapped by significant region IEA
HEPACAM hepatic and glial cell adhesion molecule Mapped by significant region IDA
PTPRK protein tyrosine phosphatase, receptor type, K Mapped by CNV; Mapped by significant region IEA
MAPT microtubule-associated protein tau Mapped by LD-proxy; Mapped by PBA pathway IDA[8642405]