ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0030425
Name dendrite
Type cellular component
No. of Genes in ADHDgene  51
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 51)

Literature-origin genes (count: 13)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
CPLX2 complexin 2 5q35.2 2(1/0/1) IEA
PEX5L peroxisomal biogenesis factor 5-like 3q27.1 1(0/0/1) IEA
GRIK1 glutamate receptor, ionotropic, kainate 1 21q22 1(0/0/1) IEA
HCN1 hyperpolarization activated cyclic nucleotide-gated potassium channel 1 5p12 1(0/1/0) IEA
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled 7q36.1 1(0/1/0) IEA
GRM7 glutamate receptor, metabotropic 7 3p26-p25 3(2/1/0) IDA[9630572]
TH tyrosine hydroxylase 11p15.5 7(2/5/0) IEA
KCNIP4 Kv channel interacting protein 4 4p15.32 1(1/0/0) IEA
CPLX1 complexin 1 4p16.3 1(1/0/0) IEA
DRD2 dopamine receptor D2 11q22-q23 10(3/7/0) ISS
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) 15q24 1(0/1/0) ISS
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled 1p36-p35 2(0/2/0) IEA
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 20q13.33 7(4/3/0) ISS

Genes from other sources Help (count: 38)

Approved Symbol Approved Name Source Evidence[PMID]
CHL1 cell adhesion molecule L1-like Mapped by CNV IEA
EPHA5 EPH receptor A5 Mapped by CNV; Mapped by significant region IDA[10375373]
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5 Mapped by CNV; Mapped by significant region IEA
ADCY4 adenylate cyclase 4 Mapped by significant region IEA
OPA1 optic atrophy 1 (autosomal dominant) Mapped by CNV ISS[11847212]
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) Mapped by significant region IEA
STRN3 striatin, calmodulin binding protein 3 Mapped by significant region ISS
KCNIP1 Kv channel interacting protein 1 Mapped by Literature SNP IEA
THY1 Thy-1 cell surface antigen Mapped by significant region IEA
KLHL1 kelch-like family member 1 Mapped by CNV IEA
CYBA cytochrome b-245, alpha polypeptide Mapped by significant region IEA
TXN thioredoxin Mapped by significant region IEA
PDE2A phosphodiesterase 2A, cGMP-stimulated Mapped by significant region IEA
AQP11 aquaporin 11 Mapped by significant region IEA
GRIA4 glutamate receptor, ionotropic, AMPA 4 Mapped by significant region IEA
CHRM3 cholinergic receptor, muscarinic 3 Mapped by CNV; Mapped by PBA pathway IEA
TSC2 tuberous sclerosis 2 Mapped by significant region IEA
PTPRK protein tyrosine phosphatase, receptor type, K Mapped by CNV; Mapped by significant region IEA
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 Mapped by CNV ISS
CNIH2 cornichon family AMPA receptor auxiliary protein 2 Mapped by significant region ISS
TRAPPC4 trafficking protein particle complex 4 Mapped by significant region ISS[11018053]
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 Mapped by significant region ISS
ADCY2 adenylate cyclase 2 (brain) Mapped by significant region ISS
DENND1A DENN/MADD domain containing 1A Mapped by significant region IEA
TAOK2 TAO kinase 2 Mapped by CNV IEA
SORT1 sortilin 1 Mapped by CNV IEA
MTMR2 myotubularin related protein 2 Mapped by significant region ISS
SKOR1 SKI family transcriptional corepressor 1 Mapped by LD-proxy IDA[17292623]
RAB27A RAB27A, member RAS oncogene family Mapped by LD-proxy IDA[11266474]
KNDC1 kinase non-catalytic C-lobe domain (KIND) containing 1 Mapped by CNV IEA
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 Mapped by significant region IEA
UBXN1 UBX domain protein 1 Mapped by significant region IEA
MAP1S microtubule-associated protein 1S Mapped by PBA pathway ISS[15528209]
UBE2I ubiquitin-conjugating enzyme E2I Mapped by significant region IEA
CADM1 cell adhesion molecule 1 Mapped by significant region IEA
ACHE acetylcholinesterase (Yt blood group) Mapped by PBA pathway IBA
CNTNAP2 contactin associated protein-like 2 Mapped by CNV ISS
NLGN1 neuroligin 1 Mapped by CNV ISS