ADHDgene Database

Gene Report

Basic Info

Approved Symbol	CHL1
Symbol Alias	CALL, L1CAM2, FLJ44930, MGC132578
Approved Name	cell adhesion molecule L1-like
Previous Name	"cell adhesion molecule with homology to L1CAM (close homologue of L1)", "cell adhesion molecule with homology to L1CAM (close homolog of L1)"
Name Alias	"neural cell adhesion molecule", "close homolog of L1"
Location	3p26
Position	chr3:238279-451090, 1
External Links	HGNC: 1939 Entrez Gene: 10752 Ensembl: ENSG00000134121 UCSC: uc003bot.3
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 2)

ID	Location	Size	Band	Type	Inheritance
CNV_Elia[2010]_35	chr3:38411-1118424 (NCBI Build 35 (hg17))	1080014	3p26.3	Duplication	Paternal
CNV_Jarick[2012]_6	chr3:38411-1102372 (NCBI36 / hg18)	1063962	3p26.3	del

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 13)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005886	plasma membrane	cellular component	IEA	839
GO:0043524	negative regulation of neuron apoptotic process	biological process	IEA	18
GO:0030425	dendrite	cellular component	IEA	51
GO:0002020	protease binding	molecular function	IEA	13
GO:0007165	signal transduction	biological process	TAS[9799093]	189
GO:0005578	proteinaceous extracellular matrix	cellular component	IEA	51
GO:0007155	cell adhesion	biological process	IEA	99
GO:0008344	adult locomotory behavior	biological process	IEA	13
GO:0045177	apical part of cell	cellular component	IEA	11
GO:0001764	neuron migration	biological process	IEA	22
GO:0016021	integral to membrane	cellular component	IEA	932
GO:0007411	axon guidance	biological process	TAS	71
GO:0050890	cognition	biological process	IEA	5

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with CHL1 (count: 1)

Gene Symbol	Pathway Count	Pathway List
CHRNA4	5	plasma membrane; dendrite; signal transduction; integral to membrane; cognition;

Genes shared at least 2 KEGG pathways with CHL1 (count: 0)

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Region: chr3:238279..451090 View in gBrowse