ADHDgene Database
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Type:
  • Large-scale studies
  • Data Summary
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0030425
Name dendrite
Type Cellular Component
No. of Genes in ADHDgene  46
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 46)

Literature-origin genes (count: 13)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
CHRNA3 cholinergic receptor, nicotinic, alpha 3 15q24 1(0/1/0)
GRM7 glutamate receptor, metabotropic 7 3p26-p25 1(1/0/0) IDA[9630572]
PEX5L peroxisomal biogenesis factor 5-like 3q27.1 1(0/0/1)
CPLX1 complexin 1 4p16.3 1(1/0/0)
HTR6 5-hydroxytryptamine (serotonin) receptor 6 1p36-p35 2(0/2/0)
CPLX2 complexin 2 5q35.2 2(1/0/1)
HCN1 hyperpolarization activated cyclic nucleotide-gated potassium channel 1 5p12 1(0/1/0)
GRIK1 glutamate receptor, ionotropic, kainate 1 21q22 1(0/0/1)
DRD2 dopamine receptor D2 11q22-q23 10(3/7/0)
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A 7q36.1 1(0/1/0)
TH tyrosine hydroxylase 11p15.5 7(2/5/0)
KCNIP4 Kv channel interacting protein 4 4p15.32 1(1/0/0)
CHRNA4 cholinergic receptor, nicotinic, alpha 4 20 7(4/3/0)

Genes from other sources Help (count: 33)

Approved Symbol Approved Name Source Evidence[PMID]
ACHE acetylcholinesterase Mapped by PBA pathway
KNDC1 kinase non-catalytic C-lobe domain (KIND) containing 1 Mapped by CNV
CNTNAP2 contactin associated protein-like 2 Mapped by CNV
OPA1 optic atrophy 1 (autosomal dominant) Mapped by CNV ISS[11847212]
UBXN1 UBX domain protein 1 Mapped by significant region
RAB27A RAB27A, member RAS oncogene family Mapped by LD-proxy IDA[11266474]
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) Mapped by significant region
PDE2A phosphodiesterase 2A, cGMP-stimulated Mapped by significant region
PTPRK protein tyrosine phosphatase, receptor type, K Mapped by CNV; Mapped by significant region
KLHL1 kelch-like 1 (Drosophila) Mapped by CNV
CADM1 cell adhesion molecule 1 Mapped by significant region
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 Mapped by CNV
EPHA5 EPH receptor A5 Mapped by CNV; Mapped by significant region IDA[10375373]
CYBA cytochrome b-245, alpha polypeptide Mapped by significant region
SORT1 sortilin 1 Mapped by CNV
AQP11 aquaporin 11 Mapped by significant region
TAOK2 TAO kinase 2 Mapped by CNV
MAP1S microtubule-associated protein 1S Mapped by PBA pathway ISS[15528209]
STRN3 striatin, calmodulin binding protein 3 Mapped by significant region
TRAPPC4 trafficking protein particle complex 4 Mapped by significant region ISS[11018053]
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 Mapped by significant region
ADCY4 adenylate cyclase 4 Mapped by significant region
CHL1 cell adhesion molecule with homology to L1CAM (close homolog of L1) Mapped by CNV
KCNIP1 Kv channel interacting protein 1 Mapped by LD-proxy; Mapped by literature SNP
NLGN1 neuroligin 1 Mapped by CNV
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5 Mapped by CNV; Mapped by significant region
CNIH2 cornichon homolog 2 (Drosophila) Mapped by significant region
THY1 Thy-1 cell surface antigen Mapped by significant region
MTMR2 myotubularin related protein 2 Mapped by significant region
DENND1A DENN/MADD domain containing 1A Mapped by significant region
TXN thioredoxin Mapped by significant region
GRIA4 glutamate receptor, ionotrophic, AMPA 4 Mapped by significant region
CHRM3 cholinergic receptor, muscarinic 3 Mapped by CNV; Mapped by PBA pathway

Copyright: Bioinformatics Lab, Institute of Psychology, Chinese Academy of Sciences Feedback
Last update: Feb 26, 2014