ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	MAP1S
Previous Symbol	C19orf5, VCY2IP1, BPY2IP1
Symbol Alias	FLJ10669, MAP8
Approved Name	microtubule-associated protein 1S
Previous Name	chromosome 19 open reading frame 5, "VCY2 interacting protein 1", "BPY2 interacting protein 1"
Location	19p13.12
Position	chr19:17830291-17845324, +
External Links	HGNC: 15715 Entrez Gene: 55201 Ensembl: ENSG00000130479 UCSC: uc002nhe.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by PBA pathway

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 25)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 1)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0000226	microtubule cytoskeleton organization	Biological Process		39

GO terms by database search (count: 24)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0001578	microtubule bundle formation	Biological Process	IMP[15528209]	8
GO:0003677	DNA binding	Molecular Function	IDA[15907802]	220
GO:0004536	deoxyribonuclease activity	Molecular Function	IDA[15907802]	1
GO:0005515	protein binding	Molecular Function	IPI[14627543]	910
GO:0005634	nucleus	Cellular Component	IDA[12762840]	770
GO:0005819	spindle	Cellular Component		29
GO:0005829	cytosol	Cellular Component	IDA[12762840]	447
GO:0005874	microtubule	Cellular Component	IDA[15528209]	52
GO:0005875	microtubule associated complex	Cellular Component		13
GO:0006915	apoptotic process	Biological Process	IDA[12762840]	111
GO:0007399	nervous system development	Biological Process	ISS[16297881]	54
GO:0007420	brain development	Biological Process	ISS[15528209]	33
GO:0042802	identical protein binding	Molecular Function		70
GO:0030425	dendrite	Cellular Component	ISS[15528209]	46
GO:0015631	tubulin binding	Molecular Function	IDA[15528209]	9
GO:0008017	microtubule binding	Molecular Function	IDA[15528209]; TAS[12762840]	32
GO:0047497	mitochondrion transport along microtubule	Biological Process	TAS[12762840]	4
GO:0045202	synapse	Cellular Component	IDA[17658481]	31
GO:0043025	neuronal cell body	Cellular Component	ISS[15528209]	51
GO:0042995	cell projection	Cellular Component	IDA[17658481]	12
GO:0051015	actin filament binding	Molecular Function	IDA[15528209,12762840]	14
GO:0048812	neuron projection morphogenesis	Biological Process	IEP[15528209]	7
GO:0048487	beta-tubulin binding	Molecular Function	IDA[12762840]	4
GO:0048471	perinuclear region of cytoplasm	Cellular Component	IDA[12762840]	87

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with MAP1S (count: 37)

Gene Symbol	Pathway Count	Pathway List
CDK5RAP2	9	microtubule cytoskeleton organization; microtubule bundle formation; protein binding; cytosol; microtubule; brain development; tubulin binding; microtubule binding; perinuclear region of cytoplasm;
ARHGEF2	8	microtubule cytoskeleton organization; protein binding; spindle; cytosol; microtubule; apoptotic process; microtubule binding; neuronal cell body;
MAPT	8	microtubule cytoskeleton organization; protein binding; cytosol; microtubule; microtubule associated complex; apoptotic process; microtubule binding; mitochondrion transport along microtubule;
PAFAH1B1	8	microtubule cytoskeleton organization; protein binding; nucleus; cytosol; microtubule associated complex; microtubule binding; neuronal cell body; perinuclear region of cytoplasm;
TPPP	8	microtubule cytoskeleton organization; microtubule bundle formation; protein binding; nucleus; microtubule; tubulin binding; microtubule binding; perinuclear region of cytoplasm;
KIF23	7	microtubule cytoskeleton organization; protein binding; nucleus; spindle; cytosol; microtubule; microtubule binding;
UXT	7	microtubule cytoskeleton organization; protein binding; nucleus; microtubule binding; mitochondrion transport along microtubule; actin filament binding; beta-tubulin binding;
MAP1B	7	microtubule bundle formation; protein binding; cytosol; microtubule; microtubule associated complex; mitochondrion transport along microtubule; synapse;
SNCA	7	protein binding; nucleus; cytosol; identical protein binding; microtubule binding; beta-tubulin binding; perinuclear region of cytoplasm;
APC	6	microtubule cytoskeleton organization; protein binding; nucleus; cytosol; apoptotic process; microtubule binding;
PRC1	6	microtubule cytoskeleton organization; protein binding; nucleus; spindle; identical protein binding; microtubule binding;
PLK1	6	microtubule bundle formation; protein binding; nucleus; spindle; cytosol; microtubule binding;
KIF22	6	DNA binding; nucleus; spindle; cytosol; microtubule; microtubule associated complex;
MAPK1	6	DNA binding; protein binding; nucleus; spindle; cytosol; apoptotic process;
ACHE	6	protein binding; nucleus; nervous system development; dendrite; synapse; perinuclear region of cytoplasm;
PAK1	6	protein binding; cytosol; apoptotic process; identical protein binding; dendrite; neuron projection morphogenesis;
CENPJ	5	microtubule cytoskeleton organization; protein binding; cytosol; microtubule; tubulin binding;
CLASP1	5	microtubule cytoskeleton organization; microtubule bundle formation; protein binding; cytosol; microtubule binding;
HOOK3	5	microtubule cytoskeleton organization; protein binding; microtubule; identical protein binding; microtubule binding;
KIF11	5	microtubule cytoskeleton organization; spindle; cytosol; microtubule; microtubule binding;
MAPRE1	5	microtubule cytoskeleton organization; protein binding; spindle; cytosol; microtubule;
MARK4	5	microtubule cytoskeleton organization; microtubule bundle formation; protein binding; nervous system development; microtubule binding;
PSRC1	5	microtubule bundle formation; protein binding; spindle; cytosol; microtubule binding;
NDN	5	DNA binding; nucleus; cytosol; nervous system development; cell projection;
PRPF19	5	DNA binding; protein binding; nucleus; spindle; identical protein binding;
RABGAP1	5	DNA binding; protein binding; cytosol; microtubule associated complex; tubulin binding;
RELA	5	DNA binding; protein binding; nucleus; cytosol; identical protein binding;
ZBTB16	5	DNA binding; protein binding; nucleus; apoptotic process; identical protein binding;
BNIP3	5	protein binding; nucleus; apoptotic process; identical protein binding; dendrite;
CEP57	5	protein binding; nucleus; cytosol; microtubule; microtubule binding;
ERBB2	5	protein binding; nucleus; nervous system development; identical protein binding; perinuclear region of cytoplasm;
GSK3B	5	protein binding; nucleus; cytosol; neuronal cell body; perinuclear region of cytoplasm;
NDE1	5	protein binding; cytosol; microtubule; identical protein binding; microtubule binding;
PDE2A	5	protein binding; nucleus; cytosol; dendrite; perinuclear region of cytoplasm;
PRKD1	5	protein binding; nucleus; cytosol; apoptotic process; identical protein binding;
PSMC3	5	protein binding; nucleus; cytosol; apoptotic process; perinuclear region of cytoplasm;
CPLX2	5	cytosol; nervous system development; dendrite; synapse; neuronal cell body;

Genes shared at least 2 KEGG pathways with MAP1S (count: 0)

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Region: chr19:17830291..17845324 View in gBrowse