ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0005819
Name spindle
Type cellular component
No. of Genes in ADHDgene  34
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 34)

Literature-origin genes (count: 2)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
MAP2K5 mitogen-activated protein kinase kinase 5 15q22.31 1(1/0/0) IEA
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) 7p22 1(0/1/0) NAS[9546394]

Genes from other sources Help (count: 32)

Approved Symbol Approved Name Source Evidence[PMID]
KIFC1 kinesin family member C1 Mapped by LD-proxy IEA
MID1 midline 1 (Opitz/BBB syndrome) Mapped by PBA pathway IEA
KIF23 kinesin family member 23 Mapped by PBA pathway IDA[15197175]
MAPRE1 microtubule-associated protein, RP/EB family, member 1 Mapped by PBA pathway IDA[11943150]
INVS inversin Mapped by significant region IEA
CLTCL1 clathrin, heavy chain-like 1 Mapped by CNV IDA[19509056]
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 Mapped by PBA pathway IEA
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae) Mapped by PBA pathway IDA
TTK TTK protein kinase Mapped by PBA pathway TAS[10366450]
PLK1 polo-like kinase 1 Mapped by significant region IDA[12939256]
PRC1 protein regulator of cytokinesis 1 Mapped by PBA pathway IDA[17351640]
PTP4A1 protein tyrosine phosphatase type IVA, member 1 Mapped by significant region IEA
PRPF19 pre-mRNA processing factor 19 Mapped by significant region IEA
MZT2A mitotic spindle organizing protein 2A Mapped by CNV; Mapped by significant region ISS
DCTN3 dynactin 3 (p22) Mapped by LD-proxy IEA
CBX3 chromobox homolog 3 Mapped by CNV; Mapped by significant region IDA[11101528]
KIF11 kinesin family member 11 Mapped by PBA pathway IDA[19001501]
SEPT12 septin 12 Mapped by significant region IDA[18047794]
PSRC1 proline/serine-rich coiled-coil 1 Mapped by CNV ISS[12427559]
KIF22 kinesin family member 22 Mapped by CNV IEA
MAPK1 mitogen-activated protein kinase 1 Mapped by LD-proxy IEA
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like Mapped by CNV IEA
SPIN1 spindlin 1 Mapped by significant region IEA
INCENP inner centromere protein antigens 135/155kDa Mapped by significant region IDA[9864353]
NUMA1 nuclear mitotic apparatus protein 1 Mapped by significant region TAS[7004645]
SAC3D1 SAC3 domain containing 1 Mapped by significant region IEA
AURKC aurora kinase C Mapped by LD-proxy TAS[19774610]
MAP1S microtubule-associated protein 1S Mapped by PBA pathway IEA
NSUN2 NOP2/Sun RNA methyltransferase family, member 2 Mapped by significant region IEA
E4F1 E4F transcription factor 1 Mapped by significant region IEA
ATM ataxia telangiectasia mutated Mapped by CNV; Mapped by significant region IEA
MZT2B mitotic spindle organizing protein 2B Mapped by significant region IDA