ADHDgene Database

Hot Results

Quick Search

Keyword:
Type:

Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	PRKD1
Previous Symbol	PRKCM
Symbol Alias	PKCM, PKD, PKC-mu
Approved Name	protein kinase D1
Previous Name	protein kinase C, mu
Location	14q11
Position	chr14:30045685-30396948, -
External Links	HGNC: 9407 Entrez Gene: 5587 Ensembl: ENSG00000184304 UCSC: uc001wqh.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
14q12	chr14:24600000-33300000	1 (1/0/0)

Gene related GO terms (count: 53)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 1)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0048193	Golgi vesicle transport	Biological Process		49

GO terms by database search (count: 52)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005794	Golgi apparatus	Cellular Component		157
GO:0005802	trans-Golgi network	Cellular Component	IDA[19211839]	28
GO:0005829	cytosol	Cellular Component		447
GO:0005886	plasma membrane	Cellular Component		772
GO:0005887	integral to plasma membrane	Cellular Component	TAS[8119958]	220
GO:0005911	cell-cell junction	Cellular Component		20
GO:0005938	cell cortex	Cellular Component		26
GO:0006644	phospholipid metabolic process	Biological Process		59
GO:0001938	positive regulation of endothelial cell proliferation	Biological Process		8
GO:0004674	protein serine/threonine kinase activity	Molecular Function	IDA[18440775]; TAS[8119958]	61
GO:0004697	protein kinase C activity	Molecular Function		2
GO:0005515	protein binding	Molecular Function		910
GO:0005524	ATP binding	Molecular Function		228
GO:0005543	phospholipid binding	Molecular Function		61
GO:0005634	nucleus	Cellular Component		770
GO:0005737	cytoplasm	Cellular Component		690
GO:0001525	angiogenesis	Biological Process		35
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Biological Process	IMP[18059339]	131
GO:0046777	protein autophosphorylation	Biological Process		23
GO:0045766	positive regulation of angiogenesis	Biological Process	IMP[18440775]	12
GO:0045806	negative regulation of endocytosis	Biological Process		3
GO:0051092	positive regulation of NF-kappaB transcription factor activity	Biological Process	IMP[12505989]	27
GO:0046872	metal ion binding	Molecular Function		170
GO:0048010	vascular endothelial growth factor receptor signaling pathway	Biological Process	IMP[18059339]	6
GO:0042802	identical protein binding	Molecular Function	IPI[19135240]	70
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade	Biological Process	IMP[12505989]	27
GO:0035924	cellular response to vascular endothelial growth factor stimulus	Biological Process	IMP[18440775]	3
GO:0038033	positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway	Biological Process	IMP[18440775]	2
GO:0045087	innate immune response	Biological Process		54
GO:0045669	positive regulation of osteoblast differentiation	Biological Process		6
GO:0043536	positive regulation of blood vessel endothelial cell migration	Biological Process	IMP[18440775]	3
GO:0044281	small molecule metabolic process	Biological Process		248
GO:0018105	peptidyl-serine phosphorylation	Biological Process	IDA[18440775]	12
GO:0010976	positive regulation of neuron projection development	Biological Process	IMP[19211839]	9
GO:0010837	regulation of keratinocyte proliferation	Biological Process		2
GO:0010595	positive regulation of endothelial cell migration	Biological Process	IMP[18332134]	7
GO:0034599	cellular response to oxidative stress	Biological Process	IDA[12505989]	5
GO:0033138	positive regulation of peptidyl-serine phosphorylation	Biological Process		10
GO:0032793	positive regulation of CREB transcription factor activity	Biological Process		6
GO:0030148	sphingolipid biosynthetic process	Biological Process		4
GO:0007030	Golgi organization	Biological Process	IMP[19211839]	11
GO:0006954	inflammatory response	Biological Process		51
GO:0006915	apoptotic process	Biological Process		111
GO:0006665	sphingolipid metabolic process	Biological Process		16
GO:0008283	cell proliferation	Biological Process	TAS[8119958]	60
GO:0007243	intracellular protein kinase cascade	Biological Process	IMP[18440775]	19
GO:0007229	integrin-mediated signaling pathway	Biological Process		10
GO:0007165	signal transduction	Biological Process	TAS[8119958]	171
GO:2001028	positive regulation of endothelial cell chemotaxis	Biological Process	IMP[18440775]	1
GO:2001044	regulation of integrin-mediated signaling pathway	Biological Process		1
GO:0060548	negative regulation of cell death	Biological Process	IMP[12505989]	5
GO:1901727	positive regulation of histone deacetylase activity	Biological Process		2

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with PRKD1 (count: 230)

Gene Symbol	Pathway Count	Pathway List
VEGFA	15	positive regulation of endothelial cell proliferation; protein binding; cytoplasm; angiogenesis; positive regulation of transcription from RNA polymerase II promoter; positive regulation of angiogenesis; vascular endothelial growth factor receptor signaling pathway; identical protein binding; cellular response to vascular endothelial growth factor stimulus; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway; positive regulation of blood vessel endothelial cell migration; positive regulation of endothelial cell migration; positive regulation of peptidyl-serine phosphorylation; positive regulation of CREB transcription factor activity; positive regulation of histone deacetylase activity;
PRKCB	13	cytosol; plasma membrane; protein serine/threonine kinase activity; protein kinase C activity; protein binding; ATP binding; nucleus; cytoplasm; positive regulation of angiogenesis; positive regulation of NF-kappaB transcription factor activity; positive regulation of I-kappaB kinase/NF-kappaB cascade; apoptotic process; signal transduction;
PAK1	12	Golgi apparatus; cytosol; plasma membrane; cell-cell junction; protein serine/threonine kinase activity; protein binding; ATP binding; cytoplasm; protein autophosphorylation; identical protein binding; positive regulation of peptidyl-serine phosphorylation; apoptotic process;
SNCA	12	Golgi apparatus; cytosol; plasma membrane; cell cortex; phospholipid metabolic process; protein binding; phospholipid binding; nucleus; cytoplasm; identical protein binding; cellular response to oxidative stress; positive regulation of peptidyl-serine phosphorylation;
MAPK1	11	Golgi apparatus; cytosol; protein serine/threonine kinase activity; protein binding; ATP binding; nucleus; cytoplasm; innate immune response; peptidyl-serine phosphorylation; apoptotic process; signal transduction;
ILK	11	cytosol; plasma membrane; cell-cell junction; protein serine/threonine kinase activity; protein binding; ATP binding; cytoplasm; positive regulation of osteoblast differentiation; peptidyl-serine phosphorylation; cell proliferation; integrin-mediated signaling pathway;
PIK3CG	11	cytosol; plasma membrane; phospholipid metabolic process; protein serine/threonine kinase activity; protein binding; ATP binding; cytoplasm; angiogenesis; innate immune response; small molecule metabolic process; inflammatory response;
FLT4	11	plasma membrane; integral to plasma membrane; positive regulation of endothelial cell proliferation; protein binding; ATP binding; nucleus; cytoplasm; protein autophosphorylation; vascular endothelial growth factor receptor signaling pathway; cellular response to vascular endothelial growth factor stimulus; positive regulation of endothelial cell migration;
GSK3B	10	cytosol; plasma membrane; protein serine/threonine kinase activity; protein binding; ATP binding; nucleus; cytoplasm; positive regulation of transcription from RNA polymerase II promoter; peptidyl-serine phosphorylation; positive regulation of peptidyl-serine phosphorylation;
MAPK7	10	cytosol; protein binding; ATP binding; nucleus; positive regulation of transcription from RNA polymerase II promoter; innate immune response; peptidyl-serine phosphorylation; apoptotic process; signal transduction; negative regulation of cell death;
RELA	10	cytosol; protein binding; nucleus; cytoplasm; positive regulation of transcription from RNA polymerase II promoter; positive regulation of NF-kappaB transcription factor activity; identical protein binding; positive regulation of I-kappaB kinase/NF-kappaB cascade; innate immune response; inflammatory response;
NEK6	10	protein serine/threonine kinase activity; protein binding; ATP binding; nucleus; cytoplasm; protein autophosphorylation; positive regulation of I-kappaB kinase/NF-kappaB cascade; peptidyl-serine phosphorylation; apoptotic process; signal transduction;
RPS6KA4	10	protein serine/threonine kinase activity; protein binding; ATP binding; nucleus; cytoplasm; positive regulation of transcription from RNA polymerase II promoter; positive regulation of NF-kappaB transcription factor activity; positive regulation of CREB transcription factor activity; inflammatory response; intracellular protein kinase cascade;
RIPK3	9	cytosol; plasma membrane; protein serine/threonine kinase activity; protein binding; ATP binding; positive regulation of NF-kappaB transcription factor activity; identical protein binding; innate immune response; signal transduction;
SMG1	9	cytosol; protein serine/threonine kinase activity; protein binding; ATP binding; nucleus; cytoplasm; protein autophosphorylation; metal ion binding; peptidyl-serine phosphorylation;
SYK	9	cytosol; plasma membrane; protein binding; ATP binding; angiogenesis; protein autophosphorylation; innate immune response; cell proliferation; integrin-mediated signaling pathway;
TGFBR1	9	plasma membrane; protein serine/threonine kinase activity; protein binding; ATP binding; angiogenesis; metal ion binding; peptidyl-serine phosphorylation; apoptotic process; signal transduction;
MAPK3	8	Golgi apparatus; cytosol; protein binding; ATP binding; nucleus; positive regulation of transcription from RNA polymerase II promoter; innate immune response; apoptotic process;
SIK2	8	Golgi apparatus; protein serine/threonine kinase activity; protein binding; ATP binding; nucleus; cytoplasm; protein autophosphorylation; intracellular protein kinase cascade;
TRIM5	8	Golgi apparatus; protein binding; nucleus; cytoplasm; positive regulation of NF-kappaB transcription factor activity; identical protein binding; positive regulation of I-kappaB kinase/NF-kappaB cascade; innate immune response;
WWOX	8	Golgi apparatus; cytosol; plasma membrane; protein binding; nucleus; cytoplasm; positive regulation of transcription from RNA polymerase II promoter; apoptotic process;
ADRBK1	8	cytosol; plasma membrane; protein binding; ATP binding; phospholipid binding; cytoplasm; peptidyl-serine phosphorylation; signal transduction;
BCAR1	8	cytosol; plasma membrane; protein binding; cytoplasm; vascular endothelial growth factor receptor signaling pathway; positive regulation of endothelial cell migration; cell proliferation; integrin-mediated signaling pathway;
MALT1	8	cytosol; plasma membrane; protein binding; nucleus; cytoplasm; positive regulation of NF-kappaB transcription factor activity; positive regulation of I-kappaB kinase/NF-kappaB cascade; innate immune response;
PYCARD	8	cytosol; protein binding; nucleus; cytoplasm; positive regulation of NF-kappaB transcription factor activity; innate immune response; inflammatory response; signal transduction;
ROCK2	8	cytosol; plasma membrane; protein serine/threonine kinase activity; protein binding; ATP binding; phospholipid binding; nucleus; metal ion binding;
UBB	8	cytosol; plasma membrane; protein binding; positive regulation of transcription from RNA polymerase II promoter; positive regulation of NF-kappaB transcription factor activity; positive regulation of I-kappaB kinase/NF-kappaB cascade; innate immune response; apoptotic process;
UBC	8	cytosol; plasma membrane; protein binding; positive regulation of transcription from RNA polymerase II promoter; positive regulation of NF-kappaB transcription factor activity; positive regulation of I-kappaB kinase/NF-kappaB cascade; innate immune response; apoptotic process;
BMPR1B	8	plasma membrane; integral to plasma membrane; protein serine/threonine kinase activity; protein binding; ATP binding; metal ion binding; positive regulation of osteoblast differentiation; inflammatory response;
ERBB2	8	plasma membrane; protein binding; ATP binding; nucleus; protein autophosphorylation; identical protein binding; cell proliferation; signal transduction;
MARK2	8	plasma membrane; protein serine/threonine kinase activity; protein binding; ATP binding; nucleus; protein autophosphorylation; positive regulation of neuron projection development; intracellular protein kinase cascade;
TLR4	8	plasma membrane; integral to plasma membrane; protein binding; cytoplasm; positive regulation of transcription from RNA polymerase II promoter; positive regulation of NF-kappaB transcription factor activity; positive regulation of I-kappaB kinase/NF-kappaB cascade; innate immune response;
ABCA1	7	Golgi apparatus; plasma membrane; integral to plasma membrane; protein binding; ATP binding; phospholipid binding; small molecule metabolic process;
ACHE	7	Golgi apparatus; plasma membrane; phospholipid metabolic process; protein binding; nucleus; small molecule metabolic process; cell proliferation;
CLASP2	7	Golgi apparatus; trans-Golgi network; cytosol; plasma membrane; cell cortex; protein binding; cytoplasm;
CRYAB	7	Golgi apparatus; cytosol; plasma membrane; protein binding; nucleus; cytoplasm; metal ion binding;
CTGF	7	Golgi apparatus; cytosol; plasma membrane; cell cortex; angiogenesis; small molecule metabolic process; integrin-mediated signaling pathway;
FES	7	Golgi apparatus; cytosol; ATP binding; cytoplasm; protein autophosphorylation; positive regulation of neuron projection development; cell proliferation;
GJA1	7	Golgi apparatus; plasma membrane; integral to plasma membrane; protein binding; positive regulation of I-kappaB kinase/NF-kappaB cascade; apoptotic process; signal transduction;
INPPL1	7	Golgi apparatus; cytosol; plasma membrane; phospholipid metabolic process; protein binding; cytoplasm; small molecule metabolic process;
OPTN	7	Golgi apparatus; trans-Golgi network; protein binding; cytoplasm; Golgi vesicle transport; Golgi organization; signal transduction;
PARK2	7	Golgi apparatus; cytosol; protein binding; nucleus; cytoplasm; positive regulation of I-kappaB kinase/NF-kappaB cascade; negative regulation of cell death;
PDE2A	7	Golgi apparatus; cytosol; plasma membrane; protein binding; nucleus; cytoplasm; metal ion binding;
PRKG1	7	Golgi apparatus; cytosol; plasma membrane; protein binding; ATP binding; cytoplasm; signal transduction;
ARRB1	7	cytosol; plasma membrane; protein binding; nucleus; cytoplasm; positive regulation of transcription from RNA polymerase II promoter; positive regulation of peptidyl-serine phosphorylation;
FADD	7	cytosol; protein binding; positive regulation of transcription from RNA polymerase II promoter; identical protein binding; positive regulation of I-kappaB kinase/NF-kappaB cascade; innate immune response; apoptotic process;
LATS2	7	cytosol; protein serine/threonine kinase activity; protein binding; ATP binding; nucleus; metal ion binding; intracellular protein kinase cascade;
MAP2K3	7	cytosol; protein serine/threonine kinase activity; protein binding; ATP binding; innate immune response; inflammatory response; signal transduction;
MTMR2	7	cytosol; phospholipid metabolic process; protein binding; nucleus; cytoplasm; negative regulation of endocytosis; small molecule metabolic process;
PLK1	7	cytosol; protein serine/threonine kinase activity; protein binding; ATP binding; nucleus; peptidyl-serine phosphorylation; cell proliferation;
PSMC3	7	cytosol; protein binding; ATP binding; nucleus; cytoplasm; small molecule metabolic process; apoptotic process;
YAP1	7	cytosol; protein binding; nucleus; cytoplasm; positive regulation of transcription from RNA polymerase II promoter; regulation of keratinocyte proliferation; cell proliferation;
ADAM8	7	plasma membrane; integral to plasma membrane; protein binding; cytoplasm; angiogenesis; positive regulation of NF-kappaB transcription factor activity; inflammatory response;
ADCY4	7	plasma membrane; protein binding; ATP binding; cytoplasm; metal ion binding; small molecule metabolic process; signal transduction;
SMPD2	7	plasma membrane; integral to plasma membrane; phospholipid metabolic process; metal ion binding; small molecule metabolic process; sphingolipid metabolic process; intracellular protein kinase cascade;
MAP3K11	7	protein serine/threonine kinase activity; protein binding; ATP binding; cytoplasm; protein autophosphorylation; identical protein binding; cell proliferation;
AATF	6	Golgi apparatus; protein binding; nucleus; cytoplasm; positive regulation of transcription from RNA polymerase II promoter; apoptotic process;
ARHGEF2	6	Golgi apparatus; cytosol; protein binding; phospholipid binding; positive regulation of NF-kappaB transcription factor activity; apoptotic process;
COG3	6	Golgi apparatus; plasma membrane; protein binding; nucleus; cytoplasm; Golgi vesicle transport;
CYBA	6	Golgi apparatus; positive regulation of endothelial cell proliferation; protein binding; metal ion binding; innate immune response; inflammatory response;
FGD3	6	Golgi apparatus; cytosol; phospholipid binding; cytoplasm; metal ion binding; apoptotic process;
NMNAT2	6	Golgi apparatus; trans-Golgi network; ATP binding; nucleus; cytoplasm; small molecule metabolic process;
PERP	6	Golgi apparatus; plasma membrane; integral to plasma membrane; nucleus; cytoplasm; apoptotic process;
SMPD4	6	Golgi apparatus; trans-Golgi network; phospholipid metabolic process; metal ion binding; small molecule metabolic process; sphingolipid metabolic process;
STRN3	6	Golgi apparatus; plasma membrane; protein binding; nucleus; cytoplasm; positive regulation of transcription from RNA polymerase II promoter;
STS	6	Golgi apparatus; plasma membrane; phospholipid metabolic process; metal ion binding; small molecule metabolic process; sphingolipid metabolic process;
YES1	6	Golgi apparatus; cytosol; plasma membrane; ATP binding; cytoplasm; protein autophosphorylation;
GOLPH3	6	trans-Golgi network; cytosol; plasma membrane; protein binding; cytoplasm; cell proliferation;
AIP	6	cytosol; plasma membrane; protein binding; nucleus; cytoplasm; signal transduction;
APC	6	cytosol; plasma membrane; protein binding; nucleus; cytoplasm; apoptotic process;
BAIAP2	6	cytosol; plasma membrane; protein binding; nucleus; cytoplasm; identical protein binding;
CASP1	6	cytosol; protein binding; positive regulation of I-kappaB kinase/NF-kappaB cascade; innate immune response; apoptotic process; signal transduction;
CSNK1E	6	cytosol; protein serine/threonine kinase activity; protein binding; ATP binding; nucleus; signal transduction;
CTNND1	6	cytosol; plasma membrane; cell-cell junction; protein binding; nucleus; cytoplasm;
IRF7	6	cytosol; protein binding; nucleus; cytoplasm; positive regulation of transcription from RNA polymerase II promoter; innate immune response;
ITK	6	cytosol; protein binding; ATP binding; phospholipid binding; metal ion binding; signal transduction;
KARS	6	cytosol; plasma membrane; ATP binding; nucleus; cytoplasm; metal ion binding;
LPIN1	6	cytosol; phospholipid metabolic process; nucleus; cytoplasm; positive regulation of transcription from RNA polymerase II promoter; small molecule metabolic process;
MEN1	6	cytosol; protein binding; nucleus; cytoplasm; positive regulation of transcription from RNA polymerase II promoter; positive regulation of osteoblast differentiation;
NCK1	6	cytosol; plasma membrane; protein binding; nucleus; cytoplasm; positive regulation of transcription from RNA polymerase II promoter;
PI4KA	6	cytosol; phospholipid metabolic process; protein binding; ATP binding; small molecule metabolic process; signal transduction;
PIK3C3	6	cytosol; phospholipid metabolic process; protein binding; ATP binding; innate immune response; small molecule metabolic process;
PIK3R1	6	cytosol; plasma membrane; phospholipid metabolic process; protein binding; positive regulation of transcription from RNA polymerase II promoter; small molecule metabolic process;
PLCE1	6	cytosol; plasma membrane; phospholipid metabolic process; protein binding; cytoplasm; cell proliferation;
PPP1CA	6	cytosol; protein binding; nucleus; cytoplasm; metal ion binding; small molecule metabolic process;
PRKAA1	6	cytosol; protein binding; ATP binding; nucleus; metal ion binding; signal transduction;
SQSTM1	6	cytosol; protein serine/threonine kinase activity; protein binding; positive regulation of transcription from RNA polymerase II promoter; identical protein binding; apoptotic process;
TH	6	cytosol; protein binding; nucleus; cytoplasm; small molecule metabolic process; sphingolipid metabolic process;
TJP1	6	cytosol; plasma membrane; protein binding; nucleus; cytoplasm; apoptotic process;
TNFAIP3	6	cytosol; protein binding; nucleus; cytoplasm; innate immune response; inflammatory response;
TRIO	6	cytosol; protein serine/threonine kinase activity; protein binding; ATP binding; phospholipid binding; apoptotic process;
TXN	6	cytosol; protein binding; innate immune response; small molecule metabolic process; cell proliferation; signal transduction;
WWP1	6	cytosol; plasma membrane; protein binding; nucleus; cytoplasm; signal transduction;
ADRA1A	6	plasma membrane; integral to plasma membrane; nucleus; apoptotic process; intracellular protein kinase cascade; signal transduction;
ADRA2A	6	plasma membrane; integral to plasma membrane; protein binding; cytoplasm; small molecule metabolic process; signal transduction;
ADRB1	6	plasma membrane; integral to plasma membrane; protein binding; nucleus; cytoplasm; apoptotic process;
APBB1	6	plasma membrane; protein binding; nucleus; cytoplasm; apoptotic process; signal transduction;
APOA1	6	plasma membrane; protein binding; phospholipid binding; nucleus; identical protein binding; small molecule metabolic process;
CACNA1A	6	plasma membrane; protein binding; nucleus; cytoplasm; metal ion binding; small molecule metabolic process;
DGKH	6	plasma membrane; ATP binding; phospholipid binding; nucleus; cytoplasm; metal ion binding;
MC1R	6	plasma membrane; integral to plasma membrane; protein binding; cytoplasm; positive regulation of transcription from RNA polymerase II promoter; intracellular protein kinase cascade;
TIRAP	6	plasma membrane; protein binding; positive regulation of NF-kappaB transcription factor activity; positive regulation of I-kappaB kinase/NF-kappaB cascade; innate immune response; inflammatory response;
WNK2	6	plasma membrane; protein serine/threonine kinase activity; ATP binding; cytoplasm; protein autophosphorylation; intracellular protein kinase cascade;
GATA6	6	phospholipid metabolic process; protein binding; nucleus; positive regulation of transcription from RNA polymerase II promoter; positive regulation of angiogenesis; apoptotic process;
PLA2G1B	6	phospholipid metabolic process; positive regulation of transcription from RNA polymerase II promoter; positive regulation of NF-kappaB transcription factor activity; small molecule metabolic process; intracellular protein kinase cascade; signal transduction;
ATM	6	protein serine/threonine kinase activity; protein binding; ATP binding; protein autophosphorylation; peptidyl-serine phosphorylation; signal transduction;
PAK7	6	protein serine/threonine kinase activity; ATP binding; nucleus; apoptotic process; cell proliferation; signal transduction;
TSSK2	6	protein serine/threonine kinase activity; protein binding; ATP binding; cytoplasm; protein autophosphorylation; identical protein binding;
MIF	6	protein binding; cytoplasm; innate immune response; positive regulation of peptidyl-serine phosphorylation; inflammatory response; cell proliferation;
TRAF1	6	protein binding; cytoplasm; positive regulation of NF-kappaB transcription factor activity; positive regulation of I-kappaB kinase/NF-kappaB cascade; apoptotic process; signal transduction;
CAMK1D	6	ATP binding; nucleus; cytoplasm; positive regulation of neuron projection development; positive regulation of CREB transcription factor activity; inflammatory response;
ABCC1	5	Golgi apparatus; plasma membrane; integral to plasma membrane; ATP binding; nucleus;
ARF6	5	Golgi apparatus; plasma membrane; cell cortex; protein binding; apoptotic process;
ATXN2	5	Golgi apparatus; trans-Golgi network; protein binding; nucleus; cytoplasm;
CEP57	5	Golgi apparatus; cytosol; protein binding; nucleus; cytoplasm;
DYNC2H1	5	Golgi apparatus; cytosol; plasma membrane; ATP binding; Golgi organization;
ENPP7	5	Golgi apparatus; plasma membrane; phospholipid metabolic process; small molecule metabolic process; sphingolipid metabolic process;
FABP6	5	Golgi apparatus; cytosol; nucleus; cytoplasm; small molecule metabolic process;
GAK	5	Golgi apparatus; protein serine/threonine kinase activity; protein binding; ATP binding; cytoplasm;
MAPRE1	5	Golgi apparatus; cytosol; protein binding; cytoplasm; cell proliferation;
NAPRT1	5	Golgi apparatus; cytosol; nucleus; cytoplasm; small molecule metabolic process;
SART1	5	Golgi apparatus; cytosol; protein binding; nucleus; cytoplasm;
SNAP23	5	Golgi apparatus; plasma membrane; protein binding; nucleus; Golgi vesicle transport;
SYTL2	5	Golgi apparatus; plasma membrane; protein binding; nucleus; cytoplasm;
TFAP2A	5	Golgi apparatus; protein binding; nucleus; cytoplasm; positive regulation of transcription from RNA polymerase II promoter;
TMED10	5	Golgi apparatus; plasma membrane; protein binding; Golgi vesicle transport; Golgi organization;
YKT6	5	Golgi apparatus; cytosol; integral to plasma membrane; cytoplasm; Golgi vesicle transport;
SNAP25	5	trans-Golgi network; plasma membrane; protein binding; cytoplasm; small molecule metabolic process;
ACACA	5	cytosol; protein binding; ATP binding; metal ion binding; small molecule metabolic process;
AIFM3	5	cytosol; plasma membrane; nucleus; cytoplasm; metal ion binding;
ALKBH8	5	cytosol; protein binding; nucleus; cytoplasm; metal ion binding;
AMOTL1	5	cytosol; protein binding; cytoplasm; identical protein binding; positive regulation of blood vessel endothelial cell migration;
ARHGEF12	5	cytosol; protein binding; phospholipid binding; cytoplasm; apoptotic process;
ARRB2	5	cytosol; plasma membrane; protein binding; nucleus; cytoplasm;
BIRC2	5	cytosol; protein binding; nucleus; positive regulation of I-kappaB kinase/NF-kappaB cascade; apoptotic process;
CAMK2D	5	cytosol; plasma membrane; ATP binding; protein autophosphorylation; peptidyl-serine phosphorylation;
CBL	5	cytosol; plasma membrane; protein binding; nucleus; cytoplasm;
CHEK1	5	cytosol; protein serine/threonine kinase activity; protein binding; ATP binding; nucleus;
CHKA	5	cytosol; phospholipid metabolic process; ATP binding; small molecule metabolic process; signal transduction;
CUL5	5	cytosol; plasma membrane; protein binding; nucleus; cell proliferation;
CYCS	5	cytosol; protein binding; nucleus; small molecule metabolic process; apoptotic process;
DAXX	5	cytosol; protein binding; nucleus; cytoplasm; apoptotic process;
EEF1D	5	cytosol; protein binding; nucleus; positive regulation of I-kappaB kinase/NF-kappaB cascade; signal transduction;
EGLN3	5	cytosol; protein binding; nucleus; cytoplasm; apoptotic process;
FBP1	5	cytosol; protein binding; cytoplasm; metal ion binding; small molecule metabolic process;
FYB	5	cytosol; protein binding; nucleus; intracellular protein kinase cascade; signal transduction;
GLUL	5	cytosol; ATP binding; identical protein binding; small molecule metabolic process; cell proliferation;
GRB10	5	cytosol; plasma membrane; protein binding; phospholipid binding; cytoplasm;
GSTP1	5	cytosol; protein binding; nucleus; cytoplasm; small molecule metabolic process;
GZMB	5	cytosol; protein binding; nucleus; cytoplasm; apoptotic process;
HERC5	5	cytosol; protein binding; nucleus; cytoplasm; innate immune response;
HK1	5	cytosol; protein binding; ATP binding; nucleus; small molecule metabolic process;
HSPA8	5	cytosol; plasma membrane; protein binding; ATP binding; nucleus;
IARS	5	cytosol; protein binding; ATP binding; nucleus; cytoplasm;
KAT5	5	cytosol; protein binding; nucleus; positive regulation of transcription from RNA polymerase II promoter; metal ion binding;
KIF2C	5	cytosol; protein binding; ATP binding; nucleus; cell proliferation;
LATS1	5	cytosol; protein serine/threonine kinase activity; protein binding; ATP binding; positive regulation of peptidyl-serine phosphorylation;
MAP1S	5	cytosol; protein binding; nucleus; identical protein binding; apoptotic process;
NCK2	5	cytosol; protein binding; cytoplasm; positive regulation of transcription from RNA polymerase II promoter; signal transduction;
NET1	5	cytosol; phospholipid binding; nucleus; apoptotic process; signal transduction;
NTRK2	5	cytosol; integral to plasma membrane; ATP binding; protein autophosphorylation; positive regulation of neuron projection development;
PAFAH1B1	5	cytosol; cell cortex; protein binding; nucleus; cytoplasm;
PDCD10	5	cytosol; plasma membrane; protein binding; angiogenesis; apoptotic process;
PDCD4	5	cytosol; protein binding; nucleus; cytoplasm; apoptotic process;
PI4K2B	5	cytosol; phospholipid metabolic process; ATP binding; cytoplasm; small molecule metabolic process;
PLA2G4C	5	cytosol; phospholipid metabolic process; phospholipid binding; small molecule metabolic process; inflammatory response;
PLCD1	5	cytosol; phospholipid metabolic process; phospholipid binding; cytoplasm; angiogenesis;
PRKAB2	5	cytosol; protein binding; identical protein binding; small molecule metabolic process; signal transduction;
PRKAR2B	5	cytosol; plasma membrane; cytoplasm; small molecule metabolic process; signal transduction;
PTS	5	cytosol; cytoplasm; metal ion binding; identical protein binding; small molecule metabolic process;
RASA1	5	cytosol; protein binding; phospholipid binding; cytoplasm; signal transduction;
SIPA1	5	cytosol; protein binding; nucleus; cell proliferation; signal transduction;
STXBP3	5	cytosol; plasma membrane; protein binding; nucleus; cytoplasm;
THY1	5	cytosol; plasma membrane; integral to plasma membrane; protein binding; angiogenesis;
UBE3A	5	cytosol; protein binding; nucleus; cytoplasm; positive regulation of transcription from RNA polymerase II promoter;
WASL	5	cytosol; plasma membrane; protein binding; nucleus; small molecule metabolic process;
ADAM17	5	plasma membrane; integral to plasma membrane; cell-cell junction; protein binding; cytoplasm;
ADORA2A	5	plasma membrane; integral to plasma membrane; protein binding; inflammatory response; apoptotic process;
ADRA1B	5	plasma membrane; integral to plasma membrane; nucleus; cell proliferation; intracellular protein kinase cascade;
ADRA2C	5	plasma membrane; integral to plasma membrane; protein binding; cytoplasm; small molecule metabolic process;
ADRB2	5	plasma membrane; integral to plasma membrane; protein binding; nucleus; positive regulation of transcription from RNA polymerase II promoter;
CACNA1C	5	plasma membrane; protein binding; cytoplasm; metal ion binding; small molecule metabolic process;
CCR5	5	plasma membrane; integral to plasma membrane; protein binding; cytoplasm; inflammatory response;
CHD1L	5	plasma membrane; protein binding; ATP binding; nucleus; cytoplasm;
CHRM3	5	plasma membrane; integral to plasma membrane; small molecule metabolic process; cell proliferation; signal transduction;
CORO1A	5	plasma membrane; protein binding; nucleus; cytoplasm; innate immune response;
CXCR2	5	plasma membrane; integral to plasma membrane; inflammatory response; apoptotic process; signal transduction;
DRD2	5	plasma membrane; integral to plasma membrane; protein binding; positive regulation of transcription from RNA polymerase II promoter; intracellular protein kinase cascade;
EHD3	5	plasma membrane; protein binding; ATP binding; nucleus; cytoplasm;
ENPP1	5	plasma membrane; protein binding; ATP binding; metal ion binding; small molecule metabolic process;
FLCN	5	plasma membrane; protein binding; nucleus; cytoplasm; positive regulation of transcription from RNA polymerase II promoter;
FRK	5	plasma membrane; protein binding; ATP binding; nucleus; cytoplasm;
FZD4	5	plasma membrane; integral to plasma membrane; cell-cell junction; protein binding; cytoplasm;
ITGAL	5	plasma membrane; metal ion binding; inflammatory response; integrin-mediated signaling pathway; signal transduction;
LPAR1	5	plasma membrane; integral to plasma membrane; protein binding; phospholipid binding; positive regulation of I-kappaB kinase/NF-kappaB cascade;
LPXN	5	plasma membrane; protein binding; nucleus; cytoplasm; signal transduction;
NEU3	5	plasma membrane; integral to plasma membrane; phospholipid metabolic process; small molecule metabolic process; sphingolipid metabolic process;
NRXN1	5	plasma membrane; integral to plasma membrane; protein binding; angiogenesis; metal ion binding;
PHLDA1	5	plasma membrane; protein binding; phospholipid binding; nucleus; apoptotic process;
PPP4C	5	plasma membrane; protein binding; nucleus; cytoplasm; metal ion binding;
PRC1	5	plasma membrane; protein binding; nucleus; cytoplasm; identical protein binding;
SCARB1	5	plasma membrane; integral to plasma membrane; cytoplasm; small molecule metabolic process; positive regulation of endothelial cell migration;
SGK1	5	plasma membrane; protein serine/threonine kinase activity; ATP binding; nucleus; apoptotic process;
STAB2	5	plasma membrane; integral to plasma membrane; cytoplasm; angiogenesis; small molecule metabolic process;
P2RX6	5	integral to plasma membrane; ATP binding; cytoplasm; identical protein binding; signal transduction;
GPSM2	5	cell cortex; protein binding; nucleus; cytoplasm; identical protein binding;
USP2	5	cell cortex; protein binding; nucleus; metal ion binding; identical protein binding;
SPTLC1	5	phospholipid metabolic process; protein binding; small molecule metabolic process; sphingolipid biosynthetic process; sphingolipid metabolic process;
AATK	5	protein serine/threonine kinase activity; protein binding; ATP binding; protein autophosphorylation; apoptotic process;
CDC42BPG	5	protein serine/threonine kinase activity; protein binding; ATP binding; phospholipid binding; cytoplasm;
MAP4K2	5	protein serine/threonine kinase activity; protein binding; ATP binding; innate immune response; intracellular protein kinase cascade;
STK36	5	protein serine/threonine kinase activity; protein binding; ATP binding; nucleus; cytoplasm;
TAOK2	5	protein serine/threonine kinase activity; ATP binding; nucleus; cytoplasm; apoptotic process;
ULK2	5	protein serine/threonine kinase activity; protein binding; ATP binding; protein autophosphorylation; signal transduction;
ATXN1	5	protein binding; nucleus; cytoplasm; positive regulation of transcription from RNA polymerase II promoter; identical protein binding;
BIRC3	5	protein binding; nucleus; cytoplasm; positive regulation of I-kappaB kinase/NF-kappaB cascade; apoptotic process;
BNIP3	5	protein binding; nucleus; cytoplasm; identical protein binding; apoptotic process;
GREM1	5	protein binding; positive regulation of transcription from RNA polymerase II promoter; positive regulation of angiogenesis; positive regulation of NF-kappaB transcription factor activity; apoptotic process;
MAVS	5	protein binding; positive regulation of transcription from RNA polymerase II promoter; positive regulation of I-kappaB kinase/NF-kappaB cascade; innate immune response; signal transduction;
MED1	5	protein binding; nucleus; angiogenesis; positive regulation of transcription from RNA polymerase II promoter; small molecule metabolic process;
MLL	5	protein binding; nucleus; positive regulation of transcription from RNA polymerase II promoter; identical protein binding; apoptotic process;
NR4A2	5	protein binding; nucleus; cytoplasm; positive regulation of transcription from RNA polymerase II promoter; signal transduction;
RBPJ	5	protein binding; nucleus; cytoplasm; angiogenesis; positive regulation of transcription from RNA polymerase II promoter;
SMC3	5	protein binding; ATP binding; nucleus; cytoplasm; signal transduction;
STAP1	5	protein binding; phospholipid binding; nucleus; cytoplasm; signal transduction;
TERF2IP	5	protein binding; nucleus; cytoplasm; positive regulation of NF-kappaB transcription factor activity; positive regulation of I-kappaB kinase/NF-kappaB cascade;
TNFRSF11A	5	protein binding; positive regulation of NF-kappaB transcription factor activity; metal ion binding; positive regulation of I-kappaB kinase/NF-kappaB cascade; signal transduction;
TRIM32	5	protein binding; nucleus; cytoplasm; positive regulation of NF-kappaB transcription factor activity; innate immune response;
XRCC5	5	protein binding; ATP binding; nucleus; cytoplasm; cell proliferation;
IL6	5	positive regulation of transcription from RNA polymerase II promoter; positive regulation of NF-kappaB transcription factor activity; positive regulation of osteoblast differentiation; positive regulation of peptidyl-serine phosphorylation; inflammatory response;

Genes shared at least 2 KEGG pathways with PRKD1 (count: 0)

View in gBrowse

Region: chr14:30045685..30396948 View in gBrowse