ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	PSMC3
Symbol Alias	TBP1, TBP-1
Approved Name	proteasome (prosome, macropain) 26S subunit, ATPase, 3
Location	11p11.2
Position	chr11:47440320-47448024, -
External Links	HGNC: 9549 Entrez Gene: 5702 Ensembl: ENSG00000165916 UCSC: uc001nfh.2
No. of Studies	1 (significant: 0; non-significant: 0; trend: 1)
Source	Literature-origin; Mapped by LD-proxy; Mapped by literature SNP

Gene related studies (count: 1)

Reference	Statistical Values/Author Comments	Result of Statistical Analysis
Hinney, A., 2011	This GWAS in a small group of clinically ascertained young German patients with ADHD and population-based controls did not reveal genome-wide significant findings. Replication attempts in further German and international samples did also not lead to a P-value(s) below 5E-08.	Trend

Gene related SNPs (count: 5)

Literature-origin SNPs (count: 1)

rs_ID	Location	Functional Annotation	No. of Studies (significant/non-significant/trend)
rs7105122	Chr11:47449544(Fwd)	upstream_gene_variant	1(0/0/1)

LD-proxies (count: 4)

rs_ID	Location	Functional Annotation
rs7948705	Chr11:47447955(Fwd)	5_prime_UTR_variant; upstream_gene_variant
rs2242511	Chr11:47441664(Fwd)	downstream_gene_variant; intron_variant
rs17790804	Chr11:47447202(Fwd)	intron_variant; nc_transcript_variant; non_coding_exon_variant
rs7105907	Chr11:47450318(Fwd)	upstream_gene_variant

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 38)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 38)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0000502	proteasome complex	Cellular Component	TAS[8811196]	14
GO:0000278	mitotic cell cycle	Biological Process		63
GO:0001824	blastocyst development	Biological Process		3
GO:0000932	cytoplasmic mRNA processing body	Cellular Component		7
GO:0000084	S phase of mitotic cell cycle	Biological Process		20
GO:0000082	G1/S transition of mitotic cell cycle	Biological Process		26
GO:0000216	M/G1 transition of mitotic cell cycle	Biological Process		13
GO:0000209	protein polyubiquitination	Biological Process		23
GO:0000075	cell cycle checkpoint	Biological Process		21
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	Biological Process		11
GO:0010467	gene expression	Biological Process		140
GO:0016032	viral reproduction	Biological Process		57
GO:0016070	RNA metabolic process	Biological Process		46
GO:0005737	cytoplasm	Cellular Component		690
GO:0005829	cytosol	Cellular Component		447
GO:0006521	regulation of cellular amino acid metabolic process	Biological Process		9
GO:0006915	apoptotic process	Biological Process		111
GO:0005515	protein binding	Molecular Function	IPI[19490896]	910
GO:0005524	ATP binding	Molecular Function		228
GO:0005634	nucleus	Cellular Component		770
GO:0005654	nucleoplasm	Cellular Component		183
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	Biological Process		17
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	Biological Process		14
GO:0003713	transcription coactivator activity	Molecular Function	TAS[8419915]	52
GO:0003714	transcription corepressor activity	Molecular Function	TAS[2194290]	29
GO:0016071	mRNA metabolic process	Biological Process		34
GO:0017111	nucleoside-triphosphatase activity	Molecular Function		5
GO:0019048	virus-host interaction	Biological Process		54
GO:0022624	proteasome accessory complex	Cellular Component		2
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	Biological Process		14
GO:0034641	cellular nitrogen compound metabolic process	Biological Process		30
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	Biological Process		14
GO:0042981	regulation of apoptotic process	Biological Process		32
GO:0044281	small molecule metabolic process	Biological Process		248
GO:0048471	perinuclear region of cytoplasm	Cellular Component		87
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	Biological Process		10
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	Biological Process		12
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	Biological Process		12

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa03050	Proteasome	7	The proteasome is a protein-destroying apparatus involved in...... The proteasome is a protein-destroying apparatus involved in many essential cellular functions, such as regulation of cell cycle, cell differentiation, signal transduction pathways, antigen processing for appropriate immune responses, stress signaling, inflammatory responses, and apoptosis. It is capable of degrading a variety of cellular proteins in a rapid and timely fashion and most substrate proteins are modified by ubiquitin before their degradation by the proteasome. The proteasome is a large protein complex consisting of a proteolytic core called the 20S particle and ancillary factors that regulate its activity in various ways. The most common form is the 26S proteasome containing one 20S core particle and two 19S regulatory particles that enable the proteasome to degrade ubiquitinated proteins by an ATP-dependent mechanism. Another form is the immunoproteasome containing two 11S regulatory particles, PA28 alpha and PA28 beta, which are induced by interferon gamma under the conditions of intensified immune response. Other regulatory particles include PA28 gamma and PA200. Although PA28 gamma also belongs to a family of activators of the 20S proteasome, it is localized within the nucleus and forms a homoheptamer. PA28 gamma has been implicated in the regulation of cell cycle progression and apoptosis. PA200 has been identified as a large nuclear protein that stimulates proteasomal hydrolysis of peptides. More...

Genes shared at least 5 GO terms with PSMC3 (count: 167)

Gene Symbol	Pathway Count	Pathway List
PSMB7	28	proteasome complex; mitotic cell cycle; S phase of mitotic cell cycle; G1/S transition of mitotic cell cycle; M/G1 transition of mitotic cell cycle; protein polyubiquitination; cell cycle checkpoint; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; gene expression; viral reproduction; RNA metabolic process; cytosol; regulation of cellular amino acid metabolic process; apoptotic process; protein binding; nucleoplasm; antigen processing and presentation of peptide antigen via MHC class I; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; mRNA metabolic process; virus-host interaction; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; cellular nitrogen compound metabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class I; regulation of apoptotic process; small molecule metabolic process; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;
PSMD5	28	proteasome complex; mitotic cell cycle; S phase of mitotic cell cycle; G1/S transition of mitotic cell cycle; M/G1 transition of mitotic cell cycle; protein polyubiquitination; cell cycle checkpoint; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; gene expression; viral reproduction; RNA metabolic process; cytosol; regulation of cellular amino acid metabolic process; apoptotic process; protein binding; nucleoplasm; antigen processing and presentation of peptide antigen via MHC class I; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; mRNA metabolic process; proteasome accessory complex; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; cellular nitrogen compound metabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class I; regulation of apoptotic process; small molecule metabolic process; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;
PSMD7	27	proteasome complex; mitotic cell cycle; S phase of mitotic cell cycle; G1/S transition of mitotic cell cycle; M/G1 transition of mitotic cell cycle; protein polyubiquitination; cell cycle checkpoint; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; gene expression; viral reproduction; RNA metabolic process; cytosol; regulation of cellular amino acid metabolic process; apoptotic process; protein binding; nucleoplasm; antigen processing and presentation of peptide antigen via MHC class I; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; mRNA metabolic process; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; cellular nitrogen compound metabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class I; regulation of apoptotic process; small molecule metabolic process; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;
PSME1	27	proteasome complex; mitotic cell cycle; S phase of mitotic cell cycle; G1/S transition of mitotic cell cycle; M/G1 transition of mitotic cell cycle; protein polyubiquitination; cell cycle checkpoint; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; gene expression; viral reproduction; RNA metabolic process; cytoplasm; cytosol; regulation of cellular amino acid metabolic process; apoptotic process; nucleoplasm; antigen processing and presentation of peptide antigen via MHC class I; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; mRNA metabolic process; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; cellular nitrogen compound metabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class I; regulation of apoptotic process; small molecule metabolic process; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;
PSME2	26	proteasome complex; mitotic cell cycle; S phase of mitotic cell cycle; G1/S transition of mitotic cell cycle; M/G1 transition of mitotic cell cycle; protein polyubiquitination; cell cycle checkpoint; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; gene expression; viral reproduction; RNA metabolic process; cytosol; regulation of cellular amino acid metabolic process; apoptotic process; nucleoplasm; antigen processing and presentation of peptide antigen via MHC class I; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; mRNA metabolic process; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; cellular nitrogen compound metabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class I; regulation of apoptotic process; small molecule metabolic process; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;
PSMA8	23	mitotic cell cycle; S phase of mitotic cell cycle; M/G1 transition of mitotic cell cycle; protein polyubiquitination; cell cycle checkpoint; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; gene expression; viral reproduction; RNA metabolic process; cytosol; regulation of cellular amino acid metabolic process; apoptotic process; nucleus; antigen processing and presentation of peptide antigen via MHC class I; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; mRNA metabolic process; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; cellular nitrogen compound metabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class I; regulation of apoptotic process; small molecule metabolic process; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;
UBB	23	mitotic cell cycle; S phase of mitotic cell cycle; G1/S transition of mitotic cell cycle; M/G1 transition of mitotic cell cycle; protein polyubiquitination; cell cycle checkpoint; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; gene expression; viral reproduction; RNA metabolic process; cytosol; apoptotic process; protein binding; nucleoplasm; antigen processing and presentation of peptide antigen via MHC class I; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; mRNA metabolic process; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class I; regulation of apoptotic process; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;
UBC	23	mitotic cell cycle; S phase of mitotic cell cycle; G1/S transition of mitotic cell cycle; M/G1 transition of mitotic cell cycle; protein polyubiquitination; cell cycle checkpoint; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; gene expression; viral reproduction; RNA metabolic process; cytosol; apoptotic process; protein binding; nucleoplasm; antigen processing and presentation of peptide antigen via MHC class I; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; mRNA metabolic process; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class I; regulation of apoptotic process; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;
XPO1	10	mitotic cell cycle; gene expression; viral reproduction; RNA metabolic process; cytoplasm; cytosol; protein binding; nucleoplasm; mRNA metabolic process; virus-host interaction;
ANAPC4	9	mitotic cell cycle; cell cycle checkpoint; cytosol; nucleus; nucleoplasm; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;
CDC26	9	mitotic cell cycle; cell cycle checkpoint; cytosol; protein binding; nucleoplasm; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;
CDC45	9	mitotic cell cycle; S phase of mitotic cell cycle; G1/S transition of mitotic cell cycle; M/G1 transition of mitotic cell cycle; cell cycle checkpoint; cytoplasm; protein binding; nucleus; nucleoplasm;
PLK1	9	mitotic cell cycle; cytosol; protein binding; ATP binding; nucleus; nucleoplasm; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;
CDT1	8	mitotic cell cycle; S phase of mitotic cell cycle; G1/S transition of mitotic cell cycle; M/G1 transition of mitotic cell cycle; cytosol; protein binding; nucleus; nucleoplasm;
SKP2	8	mitotic cell cycle; S phase of mitotic cell cycle; G1/S transition of mitotic cell cycle; protein polyubiquitination; cytosol; protein binding; nucleoplasm; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;
SMC1A	8	mitotic cell cycle; cell cycle checkpoint; gene expression; cytoplasm; protein binding; ATP binding; nucleus; nucleoplasm;
HSPA8	8	gene expression; RNA metabolic process; cytosol; protein binding; ATP binding; nucleus; mRNA metabolic process; virus-host interaction;
MAPK3	8	gene expression; cytosol; apoptotic process; protein binding; ATP binding; nucleus; nucleoplasm; virus-host interaction;
NCBP1	8	gene expression; viral reproduction; RNA metabolic process; cytosol; protein binding; nucleus; nucleoplasm; mRNA metabolic process;
RAN	8	gene expression; viral reproduction; cytoplasm; cytosol; protein binding; nucleoplasm; transcription coactivator activity; virus-host interaction;
RPS3	8	gene expression; viral reproduction; RNA metabolic process; cytoplasm; cytosol; protein binding; nucleus; mRNA metabolic process;
SMG1	8	gene expression; RNA metabolic process; cytoplasm; cytosol; protein binding; ATP binding; nucleus; mRNA metabolic process;
TAF10	8	gene expression; viral reproduction; cytoplasm; protein binding; nucleus; nucleoplasm; transcription coactivator activity; perinuclear region of cytoplasm;
YAP1	8	gene expression; cytoplasm; cytosol; protein binding; nucleus; nucleoplasm; transcription coactivator activity; transcription corepressor activity;
MAPK1	8	cytoplasm; cytosol; apoptotic process; protein binding; ATP binding; nucleus; nucleoplasm; virus-host interaction;
UBE3A	7	proteasome complex; cytoplasm; cytosol; protein binding; nucleus; transcription coactivator activity; virus-host interaction;
CCND1	7	mitotic cell cycle; S phase of mitotic cell cycle; G1/S transition of mitotic cell cycle; cytosol; protein binding; nucleus; nucleoplasm;
POLA2	7	mitotic cell cycle; S phase of mitotic cell cycle; G1/S transition of mitotic cell cycle; M/G1 transition of mitotic cell cycle; cytoplasm; nucleus; nucleoplasm;
RRM2	7	mitotic cell cycle; G1/S transition of mitotic cell cycle; cytoplasm; cytosol; protein binding; nucleoplasm; small molecule metabolic process;
DDX6	7	cytoplasmic mRNA processing body; gene expression; RNA metabolic process; cytosol; protein binding; ATP binding; mRNA metabolic process;
RQCD1	7	cytoplasmic mRNA processing body; gene expression; RNA metabolic process; cytosol; protein binding; nucleus; mRNA metabolic process;
RFWD2	7	cell cycle checkpoint; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; cytoplasm; cytosol; protein binding; nucleus; nucleoplasm;
DCPS	7	gene expression; RNA metabolic process; cytoplasm; cytosol; protein binding; nucleus; mRNA metabolic process;
NCOR1	7	gene expression; cytoplasm; protein binding; nucleus; nucleoplasm; transcription corepressor activity; small molecule metabolic process;
NEDD4L	7	gene expression; cytoplasm; cytosol; protein binding; nucleus; nucleoplasm; virus-host interaction;
RPL14	7	gene expression; viral reproduction; RNA metabolic process; cytoplasm; cytosol; protein binding; mRNA metabolic process;
RPS9	7	gene expression; viral reproduction; RNA metabolic process; cytoplasm; cytosol; protein binding; mRNA metabolic process;
SMG7	7	gene expression; RNA metabolic process; cytoplasm; cytosol; protein binding; nucleus; mRNA metabolic process;
SNW1	7	gene expression; protein binding; nucleus; nucleoplasm; transcription coactivator activity; transcription corepressor activity; virus-host interaction;
PRKD1	7	cytoplasm; cytosol; apoptotic process; protein binding; ATP binding; nucleus; small molecule metabolic process;
KIF23	6	mitotic cell cycle; cytosol; protein binding; ATP binding; nucleus; nucleoplasm;
NUMA1	6	mitotic cell cycle; cytoplasm; cytosol; protein binding; nucleus; nucleoplasm;
PAFAH1B1	6	mitotic cell cycle; cytoplasm; cytosol; protein binding; nucleus; perinuclear region of cytoplasm;
POLE	6	mitotic cell cycle; S phase of mitotic cell cycle; G1/S transition of mitotic cell cycle; M/G1 transition of mitotic cell cycle; nucleus; nucleoplasm;
PTTG1	6	mitotic cell cycle; cytoplasm; cytosol; protein binding; nucleus; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;
SMC3	6	mitotic cell cycle; cytoplasm; protein binding; ATP binding; nucleus; nucleoplasm;
PATL1	6	cytoplasmic mRNA processing body; gene expression; RNA metabolic process; cytosol; protein binding; mRNA metabolic process;
CUL5	6	G1/S transition of mitotic cell cycle; viral reproduction; cytosol; protein binding; nucleus; virus-host interaction;
RCC1	6	G1/S transition of mitotic cell cycle; viral reproduction; cytoplasm; protein binding; nucleus; nucleoplasm;
BIRC2	6	protein polyubiquitination; cytosol; apoptotic process; protein binding; nucleus; transcription coactivator activity;
BLMH	6	protein polyubiquitination; cytoplasm; cytosol; protein binding; nucleus; antigen processing and presentation of peptide antigen via MHC class I;
PARK2	6	protein polyubiquitination; cytoplasm; cytosol; protein binding; nucleus; perinuclear region of cytoplasm;
CHEK1	6	cell cycle checkpoint; cytosol; protein binding; ATP binding; nucleus; nucleoplasm;
DDB1	6	cell cycle checkpoint; cytoplasm; protein binding; nucleus; nucleoplasm; virus-host interaction;
CNOT6	6	gene expression; RNA metabolic process; cytosol; protein binding; nucleus; mRNA metabolic process;
DHX9	6	gene expression; cytoplasm; protein binding; ATP binding; nucleus; nucleoplasm;
IARS	6	gene expression; cytoplasm; cytosol; protein binding; ATP binding; nucleus;
KARS	6	gene expression; cytoplasm; cytosol; ATP binding; nucleus; virus-host interaction;
MED1	6	gene expression; protein binding; nucleus; nucleoplasm; transcription coactivator activity; small molecule metabolic process;
MEN1	6	gene expression; cytoplasm; cytosol; protein binding; nucleus; nucleoplasm;
NCOR2	6	gene expression; protein binding; nucleus; nucleoplasm; transcription corepressor activity; small molecule metabolic process;
RPL13	6	gene expression; viral reproduction; RNA metabolic process; cytosol; protein binding; mRNA metabolic process;
RPL35	6	gene expression; viral reproduction; RNA metabolic process; cytoplasm; cytosol; mRNA metabolic process;
RPS15A	6	gene expression; viral reproduction; RNA metabolic process; cytoplasm; cytosol; mRNA metabolic process;
RPS25	6	gene expression; viral reproduction; RNA metabolic process; cytoplasm; cytosol; mRNA metabolic process;
SNRPD1	6	gene expression; RNA metabolic process; cytosol; protein binding; nucleus; nucleoplasm;
SSRP1	6	gene expression; viral reproduction; cytoplasm; protein binding; nucleus; nucleoplasm;
TCEB1	6	gene expression; viral reproduction; cytosol; protein binding; nucleoplasm; virus-host interaction;
TNKS1BP1	6	gene expression; RNA metabolic process; cytoplasm; cytosol; nucleus; mRNA metabolic process;
HMGA1	6	viral reproduction; cytosol; protein binding; nucleus; nucleoplasm; virus-host interaction;
XRCC5	6	viral reproduction; cytoplasm; protein binding; ATP binding; nucleus; nucleoplasm;
PDCD4	6	RNA metabolic process; cytoplasm; cytosol; apoptotic process; protein binding; nucleus;
BNIP3	6	cytoplasm; apoptotic process; protein binding; nucleus; nucleoplasm; virus-host interaction;
DAXX	6	cytoplasm; cytosol; apoptotic process; protein binding; nucleus; virus-host interaction;
EGLN3	6	cytoplasm; cytosol; apoptotic process; protein binding; nucleus; nucleoplasm;
GSK3B	6	cytoplasm; cytosol; protein binding; ATP binding; nucleus; perinuclear region of cytoplasm;
MALT1	6	cytoplasm; cytosol; protein binding; nucleus; regulation of apoptotic process; perinuclear region of cytoplasm;
NCF2	6	cytoplasm; cytosol; protein binding; antigen processing and presentation of peptide antigen via MHC class I; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; antigen processing and presentation of exogenous peptide antigen via MHC class I;
PRKCB	6	cytoplasm; cytosol; apoptotic process; protein binding; ATP binding; nucleus;
RELA	6	cytoplasm; cytosol; protein binding; nucleus; nucleoplasm; virus-host interaction;
SMARCD3	6	cytoplasm; protein binding; nucleus; nucleoplasm; transcription coactivator activity; small molecule metabolic process;
TH	6	cytoplasm; cytosol; protein binding; nucleus; cellular nitrogen compound metabolic process; small molecule metabolic process;
KAT5	6	cytosol; protein binding; nucleus; transcription coactivator activity; virus-host interaction; perinuclear region of cytoplasm;
MAPK7	6	cytosol; apoptotic process; protein binding; ATP binding; nucleus; nucleoplasm;
RAD23B	5	proteasome complex; cytoplasm; protein binding; nucleus; nucleoplasm;
CDK5RAP2	5	mitotic cell cycle; cytoplasm; cytosol; protein binding; perinuclear region of cytoplasm;
CEP164	5	mitotic cell cycle; cytoplasm; cytosol; protein binding; nucleus;
CEP57	5	mitotic cell cycle; cytoplasm; cytosol; protein binding; nucleus;
CSNK1E	5	mitotic cell cycle; cytosol; protein binding; ATP binding; nucleus;
DHFRP1	5	mitotic cell cycle; G1/S transition of mitotic cell cycle; cytosol; nucleoplasm; small molecule metabolic process;
E2F5	5	mitotic cell cycle; gene expression; cytoplasm; protein binding; nucleoplasm;
FEN1	5	mitotic cell cycle; S phase of mitotic cell cycle; protein binding; nucleus; nucleoplasm;
KIF2C	5	mitotic cell cycle; cytosol; protein binding; ATP binding; nucleus;
POLD3	5	mitotic cell cycle; S phase of mitotic cell cycle; protein binding; nucleus; nucleoplasm;
POLD4	5	mitotic cell cycle; S phase of mitotic cell cycle; protein binding; nucleus; nucleoplasm;
PRKAR2B	5	mitotic cell cycle; cytoplasm; cytosol; small molecule metabolic process; perinuclear region of cytoplasm;
TGFBR1	5	blastocyst development; apoptotic process; protein binding; ATP binding; regulation of apoptotic process;
SQSTM1	5	cytoplasmic mRNA processing body; cytosol; apoptotic process; protein binding; nucleoplasm;
TRIM5	5	cytoplasmic mRNA processing body; cytoplasm; protein binding; nucleus; virus-host interaction;
LSM11	5	S phase of mitotic cell cycle; gene expression; protein binding; nucleus; nucleoplasm;
HINFP	5	G1/S transition of mitotic cell cycle; protein binding; nucleus; nucleoplasm; transcription coactivator activity;
LATS2	5	G1/S transition of mitotic cell cycle; cytosol; protein binding; ATP binding; nucleus;
TRIM32	5	protein polyubiquitination; cytoplasm; protein binding; nucleus; transcription coactivator activity;
ATM	5	cell cycle checkpoint; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; protein binding; ATP binding; nucleoplasm;
RAD9A	5	cell cycle checkpoint; cytoplasm; protein binding; nucleus; nucleoplasm;
CD2BP2	5	gene expression; cytoplasm; protein binding; nucleus; nucleoplasm;
CLNS1A	5	gene expression; RNA metabolic process; cytosol; protein binding; nucleus;
DDX23	5	gene expression; protein binding; ATP binding; nucleus; nucleoplasm;
DGCR8	5	gene expression; cytoplasm; protein binding; nucleus; nucleoplasm;
EFTUD2	5	gene expression; cytoplasm; protein binding; nucleus; nucleoplasm;
FAU	5	gene expression; viral reproduction; RNA metabolic process; cytosol; mRNA metabolic process;
FUS	5	gene expression; cytoplasm; protein binding; nucleus; nucleoplasm;
HNRNPA1	5	gene expression; cytoplasm; nucleus; nucleoplasm; virus-host interaction;
HNRNPA2B1	5	gene expression; cytoplasm; protein binding; nucleus; nucleoplasm;
HNRNPH1	5	gene expression; cytoplasm; protein binding; nucleus; nucleoplasm;
LSM4	5	gene expression; RNA metabolic process; cytosol; protein binding; mRNA metabolic process;
MAML1	5	gene expression; protein binding; nucleus; nucleoplasm; transcription coactivator activity;
NR4A2	5	gene expression; cytoplasm; protein binding; nucleus; nucleoplasm;
NR5A1	5	gene expression; protein binding; nucleus; nucleoplasm; transcription coactivator activity;
NRBP1	5	gene expression; protein binding; ATP binding; nucleoplasm; perinuclear region of cytoplasm;
NXF1	5	gene expression; cytosol; protein binding; nucleoplasm; virus-host interaction;
PGR	5	gene expression; cytoplasm; protein binding; nucleus; nucleoplasm;
POLR2G	5	gene expression; viral reproduction; apoptotic process; nucleus; nucleoplasm;
PRPF6	5	gene expression; protein binding; nucleus; nucleoplasm; transcription coactivator activity;
RBPJ	5	gene expression; cytoplasm; protein binding; nucleus; nucleoplasm;
RPL12	5	gene expression; viral reproduction; RNA metabolic process; cytosol; mRNA metabolic process;
RPL37	5	gene expression; viral reproduction; RNA metabolic process; cytosol; mRNA metabolic process;
RPL37A	5	gene expression; viral reproduction; RNA metabolic process; cytosol; mRNA metabolic process;
RPL38	5	gene expression; viral reproduction; RNA metabolic process; cytosol; mRNA metabolic process;
RPS12	5	gene expression; viral reproduction; RNA metabolic process; cytosol; mRNA metabolic process;
SEC61B	5	gene expression; protein binding; antigen processing and presentation of peptide antigen via MHC class I; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; antigen processing and presentation of exogenous peptide antigen via MHC class I;
SNRNP200	5	gene expression; protein binding; ATP binding; nucleus; nucleoplasm;
SNRPB	5	gene expression; RNA metabolic process; cytosol; protein binding; nucleoplasm;
SNRPD2	5	gene expression; RNA metabolic process; cytosol; protein binding; nucleoplasm;
SNRPD3	5	gene expression; RNA metabolic process; cytosol; protein binding; nucleoplasm;
SNRPG	5	gene expression; RNA metabolic process; cytosol; protein binding; nucleoplasm;
TAF13	5	gene expression; viral reproduction; protein binding; nucleus; nucleoplasm;
TAF4B	5	gene expression; viral reproduction; cytoplasm; nucleus; nucleoplasm;
BANF1	5	viral reproduction; cytosol; protein binding; nucleoplasm; virus-host interaction;
ATXN2	5	RNA metabolic process; cytoplasm; protein binding; nucleus; perinuclear region of cytoplasm;
AIP	5	cytoplasm; cytosol; protein binding; nucleus; transcription coactivator activity;
APC	5	cytoplasm; cytosol; apoptotic process; protein binding; nucleus;
EHD3	5	cytoplasm; protein binding; ATP binding; nucleus; perinuclear region of cytoplasm;
FANCC	5	cytoplasm; cytosol; protein binding; nucleus; nucleoplasm;
GSTP1	5	cytoplasm; cytosol; protein binding; nucleus; small molecule metabolic process;
GZMB	5	cytoplasm; cytosol; apoptotic process; protein binding; nucleus;
HERC5	5	cytoplasm; cytosol; protein binding; nucleus; perinuclear region of cytoplasm;
IRF7	5	cytoplasm; cytosol; protein binding; nucleus; nucleoplasm;
IRF9	5	cytoplasm; cytosol; protein binding; nucleus; nucleoplasm;
KRT18	5	cytoplasm; apoptotic process; protein binding; virus-host interaction; perinuclear region of cytoplasm;
LPIN1	5	cytoplasm; cytosol; nucleus; transcription coactivator activity; small molecule metabolic process;
MTMR2	5	cytoplasm; cytosol; protein binding; nucleus; small molecule metabolic process;
NEK6	5	cytoplasm; apoptotic process; protein binding; ATP binding; nucleus;
PAK1	5	cytoplasm; cytosol; apoptotic process; protein binding; ATP binding;
PDE2A	5	cytoplasm; cytosol; protein binding; nucleus; perinuclear region of cytoplasm;
PIK3CG	5	cytoplasm; cytosol; protein binding; ATP binding; small molecule metabolic process;
PPP1CA	5	cytoplasm; cytosol; protein binding; nucleus; small molecule metabolic process;
SART1	5	cytoplasm; cytosol; protein binding; nucleus; nucleoplasm;
SHMT1	5	cytoplasm; cytosol; nucleus; cellular nitrogen compound metabolic process; small molecule metabolic process;
SNCA	5	cytoplasm; cytosol; protein binding; nucleus; perinuclear region of cytoplasm;
TJP1	5	cytoplasm; cytosol; apoptotic process; protein binding; nucleus;
WWOX	5	cytoplasm; cytosol; apoptotic process; protein binding; nucleus;
CYCS	5	cytosol; apoptotic process; protein binding; nucleus; small molecule metabolic process;
HK1	5	cytosol; protein binding; ATP binding; nucleus; small molecule metabolic process;
MAP1S	5	cytosol; apoptotic process; protein binding; nucleus; perinuclear region of cytoplasm;
NCOA6	5	protein binding; nucleus; nucleoplasm; transcription coactivator activity; small molecule metabolic process;
SMARCB1	5	protein binding; nucleus; nucleoplasm; transcription coactivator activity; virus-host interaction;

Genes shared at least 2 KEGG pathways with PSMC3 (count: 0)

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Region: chr11:47440320..47448024 View in gBrowse