ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	CDT1
Symbol Alias	DUP, RIS2
Approved Name	chromatin licensing and DNA replication factor 1
Location	16q24.3
Position	chr16:88870186-88875666, +
External Links	HGNC: 24576 Entrez Gene: 81620 Ensembl: ENSG00000167513 UCSC: uc002flu.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
16q23.1-24.3	chr16:74100000-90354753	1 (1/0/0)

Gene related GO terms (count: 14)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 14)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0000076	DNA replication checkpoint	Biological Process	IDA[14672932]	3
GO:0000083	regulation of transcription involved in G1/S phase of mitotic cell cycle	Biological Process		7
GO:0000082	G1/S transition of mitotic cell cycle	Biological Process		26
GO:0000216	M/G1 transition of mitotic cell cycle	Biological Process		13
GO:0000084	S phase of mitotic cell cycle	Biological Process		20
GO:0003677	DNA binding	Molecular Function		220
GO:0000278	mitotic cell cycle	Biological Process		63
GO:0005634	nucleus	Cellular Component		770
GO:0005515	protein binding	Molecular Function		910
GO:0005829	cytosol	Cellular Component		447
GO:0005654	nucleoplasm	Cellular Component		183
GO:0007090	regulation of S phase of mitotic cell cycle	Biological Process		2
GO:0006260	DNA replication	Biological Process		27
GO:0030174	regulation of DNA-dependent DNA replication initiation	Biological Process	IDA[11125146]	1

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with CDT1 (count: 32)

Gene Symbol	Pathway Count	Pathway List
CDC45	10	DNA replication checkpoint; regulation of transcription involved in G1/S phase of mitotic cell cycle; G1/S transition of mitotic cell cycle; M/G1 transition of mitotic cell cycle; S phase of mitotic cell cycle; mitotic cell cycle; nucleus; protein binding; nucleoplasm; DNA replication;
POLA2	8	G1/S transition of mitotic cell cycle; M/G1 transition of mitotic cell cycle; S phase of mitotic cell cycle; DNA binding; mitotic cell cycle; nucleus; nucleoplasm; DNA replication;
POLE	8	G1/S transition of mitotic cell cycle; M/G1 transition of mitotic cell cycle; S phase of mitotic cell cycle; DNA binding; mitotic cell cycle; nucleus; nucleoplasm; DNA replication;
PSMC3	8	G1/S transition of mitotic cell cycle; M/G1 transition of mitotic cell cycle; S phase of mitotic cell cycle; mitotic cell cycle; nucleus; protein binding; cytosol; nucleoplasm;
RRM2	7	regulation of transcription involved in G1/S phase of mitotic cell cycle; G1/S transition of mitotic cell cycle; mitotic cell cycle; protein binding; cytosol; nucleoplasm; DNA replication;
CCND1	7	G1/S transition of mitotic cell cycle; S phase of mitotic cell cycle; mitotic cell cycle; nucleus; protein binding; cytosol; nucleoplasm;
PSMB7	7	G1/S transition of mitotic cell cycle; M/G1 transition of mitotic cell cycle; S phase of mitotic cell cycle; mitotic cell cycle; protein binding; cytosol; nucleoplasm;
PSMD5	7	G1/S transition of mitotic cell cycle; M/G1 transition of mitotic cell cycle; S phase of mitotic cell cycle; mitotic cell cycle; protein binding; cytosol; nucleoplasm;
PSMD7	7	G1/S transition of mitotic cell cycle; M/G1 transition of mitotic cell cycle; S phase of mitotic cell cycle; mitotic cell cycle; protein binding; cytosol; nucleoplasm;
UBB	7	G1/S transition of mitotic cell cycle; M/G1 transition of mitotic cell cycle; S phase of mitotic cell cycle; mitotic cell cycle; protein binding; cytosol; nucleoplasm;
UBC	7	G1/S transition of mitotic cell cycle; M/G1 transition of mitotic cell cycle; S phase of mitotic cell cycle; mitotic cell cycle; protein binding; cytosol; nucleoplasm;
FEN1	7	S phase of mitotic cell cycle; DNA binding; mitotic cell cycle; nucleus; protein binding; nucleoplasm; DNA replication;
HINFP	6	regulation of transcription involved in G1/S phase of mitotic cell cycle; G1/S transition of mitotic cell cycle; DNA binding; nucleus; protein binding; nucleoplasm;
PSME1	6	G1/S transition of mitotic cell cycle; M/G1 transition of mitotic cell cycle; S phase of mitotic cell cycle; mitotic cell cycle; cytosol; nucleoplasm;
PSME2	6	G1/S transition of mitotic cell cycle; M/G1 transition of mitotic cell cycle; S phase of mitotic cell cycle; mitotic cell cycle; cytosol; nucleoplasm;
SKP2	6	G1/S transition of mitotic cell cycle; S phase of mitotic cell cycle; mitotic cell cycle; protein binding; cytosol; nucleoplasm;
POLD4	6	S phase of mitotic cell cycle; mitotic cell cycle; nucleus; protein binding; nucleoplasm; DNA replication;
RAD9A	5	DNA replication checkpoint; nucleus; protein binding; nucleoplasm; DNA replication;
DHFRP1	5	regulation of transcription involved in G1/S phase of mitotic cell cycle; G1/S transition of mitotic cell cycle; mitotic cell cycle; cytosol; nucleoplasm;
RCC1	5	G1/S transition of mitotic cell cycle; nucleus; protein binding; nucleoplasm; regulation of S phase of mitotic cell cycle;
PSMA8	5	M/G1 transition of mitotic cell cycle; S phase of mitotic cell cycle; mitotic cell cycle; nucleus; cytosol;
POLD3	5	S phase of mitotic cell cycle; mitotic cell cycle; nucleus; protein binding; nucleoplasm;
HMGA1	5	DNA binding; nucleus; protein binding; cytosol; nucleoplasm;
IRF7	5	DNA binding; nucleus; protein binding; cytosol; nucleoplasm;
MAPK1	5	DNA binding; nucleus; protein binding; cytosol; nucleoplasm;
NCBP1	5	DNA binding; nucleus; protein binding; cytosol; nucleoplasm;
RELA	5	DNA binding; nucleus; protein binding; cytosol; nucleoplasm;
SSRP1	5	DNA binding; nucleus; protein binding; nucleoplasm; DNA replication;
KIF23	5	mitotic cell cycle; nucleus; protein binding; cytosol; nucleoplasm;
NUMA1	5	mitotic cell cycle; nucleus; protein binding; cytosol; nucleoplasm;
PLK1	5	mitotic cell cycle; nucleus; protein binding; cytosol; nucleoplasm;
CHEK1	5	nucleus; protein binding; cytosol; nucleoplasm; DNA replication;

Genes shared at least 2 KEGG pathways with CDT1 (count: 0)

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Region: chr16:88870186..88875666 View in gBrowse