ADHDgene Database
  • Hot Results
  • Quick Search
Keyword:
Type:
  • Large-scale studies
  • Data Summary
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0005654
Name nucleoplasm
Type Cellular Component
No. of Genes in ADHDgene  183
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 183)

Literature-origin genes (count: 10)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 11p11.2 1(0/0/1)
MAP2K3 mitogen-activated protein kinase kinase 3 17q11.2 1(0/1/0)
XPO1 exportin 1 (CRM1 homolog, yeast) 2p15 1(0/0/1)
DUSP1 dual specificity phosphatase 1 5q35.1 1(0/1/0)
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit 7q35-q36 1(0/0/1)
NR4A2 nuclear receptor subfamily 4, group A, member 2 2q22-q23 2(0/2/0)
ATXN1 ataxin 1 6p23 1(0/0/1) IDA[12757932]
NR3C2 nuclear receptor subfamily 3, group C, member 2 4q31 1(0/1/0)
LARP7 La ribonucleoprotein domain family, member 7 4q25 1(1/0/0)
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) 8q13.3 1(0/0/1)

Genes from other sources Help (count: 173)

Approved Symbol Approved Name Source Evidence[PMID]
EFTUD2 elongation factor Tu GTP binding domain containing 2 Mapped by PBA pathway
SF3A3 splicing factor 3a, subunit 3, 60kDa Mapped by PBA pathway
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa Mapped by significant region
NR5A1 nuclear receptor subfamily 5, group A, member 1 Mapped by significant region
LSM11 LSM11, U7 small nuclear RNA associated Mapped by significant region
XPA xeroderma pigmentosum, complementation group A Mapped by significant region
SF3A2 splicing factor 3a, subunit 2, 66kDa Mapped by PBA pathway
TXN thioredoxin Mapped by significant region
MED13 mediator complex subunit 13 Mapped by PBA pathway
MED15 mediator complex subunit 15 Mapped by CNV
SMC3 structural maintenance of chromosomes 3 Mapped by PBA pathway
NXF1 nuclear RNA export factor 1 Mapped by significant region
SF3B2 splicing factor 3b, subunit 2, 145kDa Mapped by PBA pathway; Mapped by significant region
MAPK3 mitogen-activated protein kinase 3 Mapped by CNV
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like Mapped by significant region
PLK1 polo-like kinase 1 Mapped by significant region
DUSP2 dual specificity phosphatase 2 Mapped by LD-proxy
RNF169 ring finger protein 169 Mapped by significant region
POLE polymerase (DNA directed), epsilon Mapped by CNV
TP53BP1 tumor protein p53 binding protein 1 Mapped by LD-proxy; Mapped by literature SNP
MED14 mediator complex subunit 14 Mapped by PBA pathway
ATM ataxia telangiectasia mutated Mapped by CNV; Mapped by significant region
DDX23 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 Mapped by PBA pathway
CDC26 cell division cycle 26 homolog (S. cerevisiae) Mapped by significant region
MED17 mediator complex subunit 17 Mapped by PBA pathway; Mapped by significant region
NR4A3 nuclear receptor subfamily 4, group A, member 3 Mapped by significant region
POLR1A polymerase (RNA) I polypeptide A, 194kDa Mapped by CNV
SNRPG small nuclear ribonucleoprotein polypeptide G Mapped by PBA pathway
MED12 mediator complex subunit 12 Mapped by PBA pathway
RFWD2 ring finger and WD repeat domain 2 Mapped by significant region
EGLN3 egl nine homolog 3 (C. elegans) Mapped by LD-proxy; Mapped by literature SNP
RCC1 regulator of chromosome condensation 1 Mapped by PBA pathway
ESRRA estrogen-related receptor alpha Mapped by significant region
TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa Mapped by CNV
H2AFX H2A histone family, member X Mapped by significant region
DROSHA drosha, ribonuclease type III Mapped by significant region
MED16 mediator complex subunit 16 Mapped by PBA pathway
PHF5A PHD finger protein 5A Mapped by PBA pathway
CDC40 cell division cycle 40 homolog (S. cerevisiae) Mapped by PBA pathway
GATA6 GATA binding protein 6 Mapped by significant region
NCOA6 nuclear receptor coactivator 6 Mapped by PBA pathway
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 Mapped by significant region
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) Mapped by CNV
POLR2G polymerase (RNA) II (DNA directed) polypeptide G Mapped by significant region
SF3A1 splicing factor 3a, subunit 1, 120kDa Mapped by PBA pathway
SNRPF small nuclear ribonucleoprotein polypeptide F Mapped by PBA pathway
GINS2 GINS complex subunit 2 (Psf2 homolog) Mapped by significant region
SMC1A structural maintenance of chromosomes 1A Mapped by PBA pathway
E2F5 E2F transcription factor 5, p130-binding Mapped by CNV
IRF7 interferon regulatory factor 7 Mapped by LD-proxy
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 Mapped by PBA pathway IDA[8521471]
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) Mapped by significant region
CDC14B CDC14 cell division cycle 14 homolog B (S. cerevisiae) Mapped by significant region IDA[18662541]
MED24 mediator complex subunit 24 Mapped by PBA pathway
NCBP1 nuclear cap binding protein subunit 1, 80kDa Mapped by significant region
TINF2 TERF1 (TRF1)-interacting nuclear factor 2 Mapped by significant region
BANF1 barrier to autointegration factor 1 Mapped by significant region
UBC ubiquitin C Mapped by CNV
POLA2 polymerase (DNA directed), alpha 2 (70kD subunit) Mapped by significant region
CDC25B cell division cycle 25 homolog B (S. pombe) Mapped by CNV
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 Mapped by significant region
TERF2IP telomeric repeat binding factor 2, interacting protein Mapped by significant region
KPNA5 karyopherin alpha 5 (importin alpha 6) Mapped by CNV; Mapped by significant region
MED23 mediator complex subunit 23 Mapped by significant region
POLD3 polymerase (DNA-directed), delta 3, accessory subunit Mapped by significant region
GRHL1 grainyhead-like 1 (Drosophila) Mapped by significant region
CENPP centromere protein P Mapped by significant region
MED1 mediator complex subunit 1 Mapped by LD-proxy; Mapped by PBA pathway
NRBP1 nuclear receptor binding protein 1 Mapped by PBA pathway
MED4 mediator complex subunit 4 Mapped by PBA pathway
SF3B3 splicing factor 3b, subunit 3, 130kDa Mapped by PBA pathway
CENPN centromere protein N Mapped by significant region
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 Mapped by CNV; Mapped by PBA pathway; Mapped by significant region
NR6A1 nuclear receptor subfamily 6, group A, member 1 Mapped by significant region
SSRP1 structure specific recognition protein 1 Mapped by significant region
DDB1 damage-specific DNA binding protein 1, 127kDa Mapped by significant region
CCND1 cyclin D1 Mapped by significant region
POLD4 polymerase (DNA-directed), delta 4 Mapped by significant region
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) Mapped by CNV
SNW1 SNW domain containing 1 Mapped by PBA pathway
SF3B4 splicing factor 3b, subunit 4, 49kDa Mapped by PBA pathway
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) Mapped by PBA pathway
MED30 mediator complex subunit 30 Mapped by PBA pathway
RORA RAR-related orphan receptor A Mapped by LD-proxy; Mapped by literature SNP
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa Mapped by CNV
YAP1 Yes-associated protein 1 Mapped by significant region
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit Mapped by CNV
NCOR2 nuclear receptor corepressor 2 Mapped by CNV
NUMA1 nuclear mitotic apparatus protein 1 Mapped by significant region
STRN3 striatin, calmodulin binding protein 3 Mapped by significant region IDA[11570823]
PRPF6 PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae) Mapped by PBA pathway
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) Mapped by significant region
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 Mapped by CNV TAS[7801128]
ZFPM1 zinc finger protein, multitype 1 Mapped by significant region
KIF23 kinesin family member 23 Mapped by PBA pathway
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 Mapped by PBA pathway
U2AF2 U2 small nuclear RNA auxiliary factor 2 Mapped by PBA pathway
RBM4 RNA binding motif protein 4 Mapped by significant region IDA[12628928]
ANAPC4 anaphase promoting complex subunit 4 Mapped by CNV
CLP1 CLP1, cleavage and polyadenylation factor I subunit, homolog (S. cerevisiae) Mapped by significant region
MED7 mediator complex subunit 7 Mapped by significant region
FUS fused in sarcoma Mapped by CNV
SNRPA1 small nuclear ribonucleoprotein polypeptide A' Mapped by PBA pathway
PRPF8 PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae) Mapped by PBA pathway
IRF9 interferon regulatory factor 9 Mapped by significant region
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) Mapped by significant region
RAD23B RAD23 homolog B (S. cerevisiae) Mapped by significant region
PCF11 PCF11, cleavage and polyadenylation factor subunit, homolog (S. cerevisiae) Mapped by significant region
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 Mapped by significant region
SNRPA small nuclear ribonucleoprotein polypeptide A Mapped by PBA pathway
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 Mapped by PBA pathway
MAML1 mastermind-like 1 (Drosophila) Mapped by CNV
SKP2 S-phase kinase-associated protein 2 (p45) Mapped by significant region
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) Mapped by significant region
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 Mapped by CNV
SART1 squamous cell carcinoma antigen recognized by T cells Mapped by significant region IDA[16687569]
RSF1 remodeling and spacing factor 1 Mapped by significant region
ERCC8 excision repair cross-complementing rodent repair deficiency, complementation group 8 Mapped by CNV
UBB ubiquitin B Mapped by significant region
CAMK2D calcium/calmodulin-dependent protein kinase II delta Mapped by CNV
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) Mapped by significant region
MEN1 multiple endocrine neoplasia I Mapped by significant region
MAPK1 mitogen-activated protein kinase 1 Mapped by LD-proxy
RAD1 RAD1 homolog (S. pombe) Mapped by significant region
HEMGN hemogen Mapped by significant region
DHX9 DEAH (Asp-Glu-Ala-His) box polypeptide 9 Mapped by significant region
MAML2 mastermind-like 2 (Drosophila) Mapped by significant region
HINFP histone H4 transcription factor Mapped by significant region IDA[11553631]
NMD3 NMD3 homolog (S. cerevisiae) Mapped by CNV
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) Mapped by LD-proxy
FANCA Fanconi anemia, complementation group A Mapped by significant region
PRPF4 PRP4 pre-mRNA processing factor 4 homolog (yeast) Mapped by significant region
FANCC Fanconi anemia, complementation group C Mapped by significant region
TRIP12 thyroid hormone receptor interactor 12 Mapped by PBA pathway
CHEK1 CHK1 checkpoint homolog (S. pombe) Mapped by significant region
RAN RAN, member RAS oncogene family Mapped by PBA pathway
KDM1A lysine (K)-specific demethylase 1A Mapped by LD-proxy
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa Mapped by CNV
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 Mapped by significant region
MAPK9 mitogen-activated protein kinase 9 Mapped by CNV
HMGA1 high mobility group AT-hook 1 Mapped by PBA pathway
POLR3E polymerase (RNA) III (DNA directed) polypeptide E (80kD) Mapped by CNV; Mapped by significant region
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) Mapped by CNV; Mapped by significant region
CDT1 chromatin licensing and DNA replication factor 1 Mapped by significant region
PALB2 partner and localizer of BRCA2 Mapped by significant region
TXNL4A thioredoxin-like 4A Mapped by PBA pathway
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa Mapped by CNV; Mapped by PBA pathway
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa Mapped by PBA pathway
TAF1B TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa Mapped by significant region
RBPJ recombination signal binding protein for immunoglobulin kappa J region Mapped by CNV
JMJD1C jumonji domain containing 1C Mapped by PBA pathway
NCOR1 nuclear receptor corepressor 1 Mapped by significant region
ZCRB1 zinc finger CCHC-type and RNA binding motif 1 Mapped by PBA pathway
CD2BP2 CD2 (cytoplasmic tail) binding protein 2 Mapped by CNV IDA[15840814]
DGCR8 DiGeorge syndrome critical region gene 8 Mapped by CNV
U2AF1 U2 small nuclear RNA auxiliary factor 1 Mapped by PBA pathway
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa Mapped by CNV; Mapped by significant region
PGR progesterone receptor Mapped by significant region
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa Mapped by significant region
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 Mapped by significant region
RAD9A RAD9 homolog A (S. pombe) Mapped by significant region
MAPK7 mitogen-activated protein kinase 7 Mapped by significant region
SQSTM1 sequestosome 1 Mapped by CNV
RRM2 ribonucleotide reductase M2 Mapped by significant region
CDC45 cell division cycle 45 homolog (S. cerevisiae) Mapped by CNV
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa Mapped by significant region
DHFRP1 dihydrofolate reductase pseudogene 1 Mapped by significant region
ATF6 activating transcription factor 6 Mapped by CNV
USP28 ubiquitin specific peptidase 28 Mapped by significant region IDA[17558397]
CPSF3 cleavage and polyadenylation specific factor 3, 73kDa Mapped by significant region
SNRPB2 small nuclear ribonucleoprotein polypeptide B Mapped by PBA pathway
FEN1 flap structure-specific endonuclease 1 Mapped by LD-proxy; Mapped by literature SNP; Mapped by significant region
KDM2A lysine (K)-specific demethylase 2A Mapped by significant region

Copyright: Bioinformatics Lab, Institute of Psychology, Chinese Academy of Sciences Feedback
Last update: Feb 26, 2014