ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	MED7
Previous Symbol	CRSP9
Symbol Alias	CRSP33
Approved Name	mediator complex subunit 7
Previous Name	cofactor required for Sp1 transcriptional activation, subunit 9, 33kDa
Location	5q33.3
Position	chr5:156564423-156586030, -
External Links	HGNC: 2378 Entrez Gene: 9443 Ensembl: ENSG00000155868 UCSC: uc003lwm.3
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
5q33.3	chr5:155700000-159900000	1 (1/0/0)

Gene related GO terms (count: 10)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 10)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0006367	transcription initiation from RNA polymerase II promoter	Biological Process		42
GO:0006357	regulation of transcription from RNA polymerase II promoter	Biological Process	IDA[9989412]	42
GO:0016592	mediator complex	Cellular Component		17
GO:0010467	gene expression	Biological Process		140
GO:0005515	protein binding	Molecular Function	IPI[18391015]	910
GO:0003713	transcription coactivator activity	Molecular Function	TAS[9989412]	52
GO:0005667	transcription factor complex	Cellular Component	IDA[9989412]	51
GO:0005654	nucleoplasm	Cellular Component		183
GO:0001104	RNA polymerase II transcription cofactor activity	Molecular Function		16
GO:0019827	stem cell maintenance	Biological Process		12

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with MED7 (count: 20)

Gene Symbol	Pathway Count	Pathway List
MED17	9	transcription initiation from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; mediator complex; gene expression; transcription coactivator activity; transcription factor complex; nucleoplasm; RNA polymerase II transcription cofactor activity; stem cell maintenance;
MED14	8	transcription initiation from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; mediator complex; gene expression; transcription coactivator activity; nucleoplasm; RNA polymerase II transcription cofactor activity; stem cell maintenance;
MED23	8	transcription initiation from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; mediator complex; gene expression; protein binding; transcription coactivator activity; transcription factor complex; nucleoplasm;
MED1	7	transcription initiation from RNA polymerase II promoter; mediator complex; gene expression; protein binding; transcription coactivator activity; nucleoplasm; RNA polymerase II transcription cofactor activity;
MED12	7	transcription initiation from RNA polymerase II promoter; mediator complex; gene expression; transcription coactivator activity; nucleoplasm; RNA polymerase II transcription cofactor activity; stem cell maintenance;
MED15	7	transcription initiation from RNA polymerase II promoter; mediator complex; gene expression; protein binding; nucleoplasm; RNA polymerase II transcription cofactor activity; stem cell maintenance;
MED30	7	transcription initiation from RNA polymerase II promoter; mediator complex; gene expression; protein binding; nucleoplasm; RNA polymerase II transcription cofactor activity; stem cell maintenance;
MED13	6	transcription initiation from RNA polymerase II promoter; mediator complex; gene expression; transcription coactivator activity; nucleoplasm; RNA polymerase II transcription cofactor activity;
MED16	6	transcription initiation from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; mediator complex; gene expression; transcription coactivator activity; nucleoplasm;
MED24	6	transcription initiation from RNA polymerase II promoter; mediator complex; gene expression; nucleoplasm; RNA polymerase II transcription cofactor activity; stem cell maintenance;
MED4	6	transcription initiation from RNA polymerase II promoter; mediator complex; gene expression; protein binding; nucleoplasm; RNA polymerase II transcription cofactor activity;
SNW1	6	transcription initiation from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; gene expression; protein binding; transcription coactivator activity; nucleoplasm;
YAP1	6	transcription initiation from RNA polymerase II promoter; gene expression; protein binding; transcription coactivator activity; transcription factor complex; nucleoplasm;
E2F5	5	transcription initiation from RNA polymerase II promoter; gene expression; protein binding; transcription factor complex; nucleoplasm;
MAML1	5	transcription initiation from RNA polymerase II promoter; gene expression; protein binding; transcription coactivator activity; nucleoplasm;
NCOA6	5	transcription initiation from RNA polymerase II promoter; protein binding; transcription coactivator activity; transcription factor complex; nucleoplasm;
NCOR1	5	transcription initiation from RNA polymerase II promoter; gene expression; protein binding; transcription factor complex; nucleoplasm;
NR5A1	5	transcription initiation from RNA polymerase II promoter; gene expression; protein binding; transcription coactivator activity; nucleoplasm;
TAF10	5	transcription initiation from RNA polymerase II promoter; gene expression; protein binding; transcription coactivator activity; nucleoplasm;
THRAP3	5	transcription initiation from RNA polymerase II promoter; mediator complex; protein binding; transcription coactivator activity; RNA polymerase II transcription cofactor activity;

Genes shared at least 2 KEGG pathways with MED7 (count: 0)

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Region: chr5:156564423..156586030 View in gBrowse