ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

GO Report

Basic Info

ID	GO:0010467
Name	gene expression
Type	Biological Process
No. of Genes in ADHDgene	140
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 140)

Literature-origin genes (count: 5)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
PSMC3	proteasome (prosome, macropain) 26S subunit, ATPase, 3	11p11.2	1(0/0/1)
NR4A2	nuclear receptor subfamily 4, group A, member 2	2q22-q23	2(0/2/0)
XPO1	exportin 1 (CRM1 homolog, yeast)	2p15	1(0/0/1)
NR3C2	nuclear receptor subfamily 3, group C, member 2	4q31	1(0/1/0)
TCEB1	transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)	8q13.3	1(0/0/1)

Genes from other sources (count: 135)

Approved Symbol	Approved Name	Source
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	Mapped by significant region
PGR	progesterone receptor	Mapped by significant region
MED15	mediator complex subunit 15	Mapped by CNV
MAPK3	mitogen-activated protein kinase 3	Mapped by CNV
CNOT6	CCR4-NOT transcription complex, subunit 6	Mapped by CNV
MED13	mediator complex subunit 13	Mapped by PBA pathway
SF3A2	splicing factor 3a, subunit 2, 66kDa	Mapped by PBA pathway
LSM11	LSM11, U7 small nuclear RNA associated	Mapped by significant region
CPSF3	cleavage and polyadenylation specific factor 3, 73kDa	Mapped by significant region
KARS	lysyl-tRNA synthetase	Mapped by significant region
SNRPG	small nuclear ribonucleoprotein polypeptide G	Mapped by PBA pathway
SEC61B	Sec61 beta subunit	Mapped by significant region
MED12	mediator complex subunit 12	Mapped by PBA pathway
NXF1	nuclear RNA export factor 1	Mapped by significant region
MED14	mediator complex subunit 14	Mapped by PBA pathway
RPL35	ribosomal protein L35	Mapped by significant region
NR4A3	nuclear receptor subfamily 4, group A, member 3	Mapped by significant region
TARS	threonyl-tRNA synthetase	Mapped by significant region
SF3A3	splicing factor 3a, subunit 3, 60kDa	Mapped by PBA pathway
CPSF7	cleavage and polyadenylation specific factor 7, 59kDa	Mapped by significant region
SMG7	smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)	Mapped by significant region
SPCS2	signal peptidase complex subunit 2 homolog (S. cerevisiae)	Mapped by significant region
SNRPF	small nuclear ribonucleoprotein polypeptide F	Mapped by PBA pathway
DDX23	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23	Mapped by PBA pathway
DARS2	aspartyl-tRNA synthetase 2, mitochondrial	Mapped by significant region
UBC	ubiquitin C	Mapped by CNV
MED17	mediator complex subunit 17	Mapped by PBA pathway; Mapped by significant region
RPL14	ribosomal protein L14	Mapped by literature SNP
SMG1	smg-1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)	Mapped by significant region
ESRRA	estrogen-related receptor alpha	Mapped by significant region
SEC11C	SEC11 homolog C (S. cerevisiae)	Mapped by significant region
RPS9	ribosomal protein S9	Mapped by CNV
SF3A1	splicing factor 3a, subunit 1, 120kDa	Mapped by PBA pathway
CDC40	cell division cycle 40 homolog (S. cerevisiae)	Mapped by PBA pathway
RPL13	ribosomal protein L13	Mapped by significant region
DROSHA	drosha, ribonuclease type III	Mapped by significant region
PSMB7	proteasome (prosome, macropain) subunit, beta type, 7	Mapped by significant region
TAF10	TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa	Mapped by CNV
EFTUD2	elongation factor Tu GTP binding domain containing 2	Mapped by PBA pathway
PHF5A	PHD finger protein 5A	Mapped by PBA pathway
POLR1A	polymerase (RNA) I polypeptide A, 194kDa	Mapped by CNV
MED16	mediator complex subunit 16	Mapped by PBA pathway
RPL12	ribosomal protein L12	Mapped by significant region
HNRNPA1	heterogeneous nuclear ribonucleoprotein A1	Mapped by PBA pathway
MED24	mediator complex subunit 24	Mapped by PBA pathway
FAU	Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed	Mapped by significant region
MED1	mediator complex subunit 1	Mapped by LD-proxy; Mapped by PBA pathway
DHX9	DEAH (Asp-Glu-Ala-His) box polypeptide 9	Mapped by significant region
SSRP1	structure specific recognition protein 1	Mapped by significant region
DDX6	DEAD (Asp-Glu-Ala-Asp) box polypeptide 6	Mapped by significant region
PSMA8	proteasome (prosome, macropain) subunit, alpha type, 8	Mapped by significant region
NRBP1	nuclear receptor binding protein 1	Mapped by PBA pathway
E2F5	E2F transcription factor 5, p130-binding	Mapped by CNV
NCBP1	nuclear cap binding protein subunit 1, 80kDa	Mapped by significant region
MED23	mediator complex subunit 23	Mapped by significant region
SF3B3	splicing factor 3b, subunit 3, 130kDa	Mapped by PBA pathway
HNRNPA2B1	heterogeneous nuclear ribonucleoprotein A2/B1	Mapped by CNV; Mapped by PBA pathway; Mapped by significant region
RORA	RAR-related orphan receptor A	Mapped by LD-proxy; Mapped by literature SNP
SRPR	signal recognition particle receptor (docking protein)	Mapped by significant region
UBB	ubiquitin B	Mapped by significant region
EARS2	glutamyl-tRNA synthetase 2, mitochondrial (putative)	Mapped by significant region
SF3B2	splicing factor 3b, subunit 2, 145kDa	Mapped by PBA pathway; Mapped by significant region
NR6A1	nuclear receptor subfamily 6, group A, member 1	Mapped by significant region
MED4	mediator complex subunit 4	Mapped by PBA pathway
CTGF	connective tissue growth factor	Mapped by significant region
PRPF8	PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae)	Mapped by PBA pathway
RPS3	ribosomal protein S3	Mapped by significant region
SRP19	signal recognition particle 19kDa	Mapped by LD-proxy
SF3B4	splicing factor 3b, subunit 4, 49kDa	Mapped by PBA pathway
MED30	mediator complex subunit 30	Mapped by PBA pathway
NR5A1	nuclear receptor subfamily 5, group A, member 1	Mapped by significant region
LSM4	LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)	Mapped by PBA pathway
SNW1	SNW domain containing 1	Mapped by PBA pathway
HNRNPC	heterogeneous nuclear ribonucleoprotein C (C1/C2)	Mapped by PBA pathway
SMC1A	structural maintenance of chromosomes 1A	Mapped by PBA pathway
HNRNPH1	heterogeneous nuclear ribonucleoprotein H1 (H)	Mapped by CNV
NARS2	asparaginyl-tRNA synthetase 2, mitochondrial (putative)	Mapped by significant region
PSME2	proteasome (prosome, macropain) activator subunit 2 (PA28 beta)	Mapped by significant region
PRPF4	PRP4 pre-mRNA processing factor 4 homolog (yeast)	Mapped by significant region
SNRPB	small nuclear ribonucleoprotein polypeptides B and B1	Mapped by PBA pathway
RPS25	ribosomal protein S25	Mapped by significant region
U2AF2	U2 small nuclear RNA auxiliary factor 2	Mapped by PBA pathway
TAF4B	TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa	Mapped by significant region
NCOR2	nuclear receptor corepressor 2	Mapped by CNV
EIF2B1	eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa	Mapped by CNV
MED7	mediator complex subunit 7	Mapped by significant region
PCF11	PCF11, cleavage and polyadenylation factor subunit, homolog (S. cerevisiae)	Mapped by significant region
SNRPA1	small nuclear ribonucleoprotein polypeptide A'	Mapped by PBA pathway
PRPF6	PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae)	Mapped by PBA pathway
YAP1	Yes-associated protein 1	Mapped by significant region
NARS	asparaginyl-tRNA synthetase	Mapped by significant region
U2AF1	U2 small nuclear RNA auxiliary factor 1	Mapped by PBA pathway
CLP1	CLP1, cleavage and polyadenylation factor I subunit, homolog (S. cerevisiae)	Mapped by significant region
SNRPA	small nuclear ribonucleoprotein polypeptide A	Mapped by PBA pathway
FUS	fused in sarcoma	Mapped by CNV
RPS15A	ribosomal protein S15a	Mapped by significant region
SARS	seryl-tRNA synthetase	Mapped by CNV
MAML1	mastermind-like 1 (Drosophila)	Mapped by CNV
PATL1	protein associated with topoisomerase II homolog 1 (yeast)	Mapped by significant region
SNRNP200	small nuclear ribonucleoprotein 200kDa (U5)	Mapped by LD-proxy
PSME1	proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)	Mapped by significant region
RPS12	ribosomal protein S12	Mapped by significant region
GTF2H3	general transcription factor IIH, polypeptide 3, 34kDa	Mapped by CNV
MAML2	mastermind-like 2 (Drosophila)	Mapped by significant region
CLNS1A	chloride channel, nucleotide-sensitive, 1A	Mapped by significant region
DCPS	decapping enzyme, scavenger	Mapped by significant region
POLR2G	polymerase (RNA) II (DNA directed) polypeptide G	Mapped by significant region
HSPA8	heat shock 70kDa protein 8	Mapped by significant region
TXNL4A	thioredoxin-like 4A	Mapped by PBA pathway
SNRPD3	small nuclear ribonucleoprotein D3 polypeptide 18kDa	Mapped by CNV; Mapped by PBA pathway
RRN3	RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)	Mapped by CNV; Mapped by significant region
POLR3E	polymerase (RNA) III (DNA directed) polypeptide E (80kD)	Mapped by CNV; Mapped by significant region
PSMD7	proteasome (prosome, macropain) 26S subunit, non-ATPase, 7	Mapped by significant region
RBPJ	recombination signal binding protein for immunoglobulin kappa J region	Mapped by CNV
CD2BP2	CD2 (cytoplasmic tail) binding protein 2	Mapped by CNV
RAN	RAN, member RAS oncogene family	Mapped by PBA pathway
RPL38	ribosomal protein L38	Mapped by CNV
SNRPD2	small nuclear ribonucleoprotein D2 polypeptide 16.5kDa	Mapped by PBA pathway
MEN1	multiple endocrine neoplasia I	Mapped by significant region
TNKS1BP1	tankyrase 1 binding protein 1, 182kDa	Mapped by significant region
TAF13	TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa	Mapped by CNV
DGCR8	DiGeorge syndrome critical region gene 8	Mapped by CNV
NCOR1	nuclear receptor corepressor 1	Mapped by significant region
TAF1C	TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa	Mapped by CNV; Mapped by significant region
SNRPD1	small nuclear ribonucleoprotein D1 polypeptide 16kDa	Mapped by significant region
TAF1B	TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa	Mapped by significant region
RQCD1	RCD1 required for cell differentiation1 homolog (S. pombe)	Mapped by significant region
PSMD5	proteasome (prosome, macropain) 26S subunit, non-ATPase, 5	Mapped by significant region
RPL37A	ribosomal protein L37a	Mapped by significant region
SNRPB2	small nuclear ribonucleoprotein polypeptide B	Mapped by PBA pathway
FMN1	formin 1	Mapped by CNV; Mapped by significant region
IARS	isoleucyl-tRNA synthetase	Mapped by significant region
EEF1D	eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)	Mapped by LD-proxy; Mapped by literature SNP
RPL37	ribosomal protein L37	Mapped by significant region
EEF1G	eukaryotic translation elongation factor 1 gamma	Mapped by significant region