ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	SF3B3
Symbol Alias	SAP130, SF3b130, RSE1, KIAA0017
Approved Name	splicing factor 3b, subunit 3, 130kDa
Previous Name	"splicing factor 3b, subunit 3, 130kD"
Location	16q22
Position	chr16:70557691-70608820, 1
External Links	HGNC: 10770 Entrez Gene: 23450 Ensembl: ENSG00000189091 UCSC: uc002ezf.3
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by PBA pathway

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 12)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 1)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005681	spliceosomal complex	cellular component	TAS[10490618]	43

GO terms by database search (count: 11)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0006461	protein complex assembly	biological process	TAS[10490618]	32
GO:0005654	nucleoplasm	cellular component	TAS	210
GO:0008380	RNA splicing	biological process	TAS	70
GO:0003676	nucleic acid binding	molecular function	IEA	46
GO:0005689	U12-type spliceosomal complex	cellular component	IDA[15146077]	17
GO:0000398	mRNA splicing, via spliceosome	biological process	IC[11991638]; TAS	58
GO:0030532	small nuclear ribonucleoprotein complex	cellular component	TAS[10490618]	12
GO:0071013	catalytic step 2 spliceosome	cellular component	IDA[11991638]	33
GO:0000375	RNA splicing, via transesterification reactions	biological process	TAS[10490618]	12
GO:0006397	mRNA processing	biological process	TAS[10490618]	53
GO:0010467	gene expression	biological process	TAS	154

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with SF3B3 (count: 38)

Gene Symbol	Pathway Count	Pathway List
SNRPD3	9	nucleoplasm; RNA splicing; U12-type spliceosomal complex; mRNA splicing, via spliceosome; spliceosomal complex; small nuclear ribonucleoprotein complex; catalytic step 2 spliceosome; mRNA processing; gene expression;
SF3A2	9	nucleoplasm; RNA splicing; nucleic acid binding; mRNA splicing, via spliceosome; spliceosomal complex; small nuclear ribonucleoprotein complex; catalytic step 2 spliceosome; mRNA processing; gene expression;
SNRPB	9	nucleoplasm; RNA splicing; U12-type spliceosomal complex; mRNA splicing, via spliceosome; spliceosomal complex; small nuclear ribonucleoprotein complex; catalytic step 2 spliceosome; mRNA processing; gene expression;
SF3A3	9	nucleoplasm; RNA splicing; nucleic acid binding; mRNA splicing, via spliceosome; spliceosomal complex; catalytic step 2 spliceosome; RNA splicing, via transesterification reactions; mRNA processing; gene expression;
SF3B2	9	nucleoplasm; RNA splicing; nucleic acid binding; U12-type spliceosomal complex; mRNA splicing, via spliceosome; spliceosomal complex; catalytic step 2 spliceosome; mRNA processing; gene expression;
SNRPG	9	nucleoplasm; RNA splicing; U12-type spliceosomal complex; mRNA splicing, via spliceosome; spliceosomal complex; small nuclear ribonucleoprotein complex; catalytic step 2 spliceosome; mRNA processing; gene expression;
SNRPF	9	nucleoplasm; RNA splicing; U12-type spliceosomal complex; mRNA splicing, via spliceosome; spliceosomal complex; small nuclear ribonucleoprotein complex; catalytic step 2 spliceosome; mRNA processing; gene expression;
SNRPD2	8	nucleoplasm; RNA splicing; U12-type spliceosomal complex; mRNA splicing, via spliceosome; spliceosomal complex; small nuclear ribonucleoprotein complex; catalytic step 2 spliceosome; gene expression;
SF3B4	8	nucleoplasm; RNA splicing; U12-type spliceosomal complex; mRNA splicing, via spliceosome; spliceosomal complex; RNA splicing, via transesterification reactions; mRNA processing; gene expression;
U2AF1	7	nucleoplasm; RNA splicing; mRNA splicing, via spliceosome; spliceosomal complex; catalytic step 2 spliceosome; mRNA processing; gene expression;
SNRNP200	7	nucleoplasm; RNA splicing; nucleic acid binding; mRNA splicing, via spliceosome; spliceosomal complex; catalytic step 2 spliceosome; gene expression;
PRPF8	7	nucleoplasm; RNA splicing; mRNA splicing, via spliceosome; catalytic step 2 spliceosome; RNA splicing, via transesterification reactions; mRNA processing; gene expression;
SF3A1	7	nucleoplasm; RNA splicing; mRNA splicing, via spliceosome; spliceosomal complex; catalytic step 2 spliceosome; mRNA processing; gene expression;
SNRPD1	7	nucleoplasm; RNA splicing; U12-type spliceosomal complex; mRNA splicing, via spliceosome; small nuclear ribonucleoprotein complex; catalytic step 2 spliceosome; gene expression;
SNRPA1	7	nucleoplasm; RNA splicing; mRNA splicing, via spliceosome; spliceosomal complex; small nuclear ribonucleoprotein complex; catalytic step 2 spliceosome; gene expression;
SNRPB2	7	nucleoplasm; RNA splicing; mRNA splicing, via spliceosome; spliceosomal complex; catalytic step 2 spliceosome; mRNA processing; gene expression;
DDX23	7	nucleoplasm; RNA splicing; nucleic acid binding; mRNA splicing, via spliceosome; catalytic step 2 spliceosome; RNA splicing, via transesterification reactions; gene expression;
HNRNPA1	7	nucleoplasm; RNA splicing; mRNA splicing, via spliceosome; spliceosomal complex; catalytic step 2 spliceosome; mRNA processing; gene expression;
HNRNPA2B1	7	nucleoplasm; RNA splicing; mRNA splicing, via spliceosome; spliceosomal complex; catalytic step 2 spliceosome; mRNA processing; gene expression;
EFTUD2	7	nucleoplasm; RNA splicing; mRNA splicing, via spliceosome; spliceosomal complex; catalytic step 2 spliceosome; mRNA processing; gene expression;
PRPF6	7	nucleoplasm; RNA splicing; mRNA splicing, via spliceosome; spliceosomal complex; catalytic step 2 spliceosome; RNA splicing, via transesterification reactions; gene expression;
CDC40	6	nucleoplasm; RNA splicing; mRNA splicing, via spliceosome; spliceosomal complex; catalytic step 2 spliceosome; gene expression;
HNRNPC	6	nucleoplasm; RNA splicing; mRNA splicing, via spliceosome; spliceosomal complex; catalytic step 2 spliceosome; gene expression;
TXNL4A	6	nucleoplasm; RNA splicing; mRNA splicing, via spliceosome; spliceosomal complex; RNA splicing, via transesterification reactions; gene expression;
PRPF4	6	nucleoplasm; RNA splicing; mRNA splicing, via spliceosome; spliceosomal complex; RNA splicing, via transesterification reactions; gene expression;
U2AF2	6	nucleoplasm; RNA splicing; mRNA splicing, via spliceosome; spliceosomal complex; mRNA processing; gene expression;
GEMIN2	6	nucleoplasm; RNA splicing; spliceosomal complex; RNA splicing, via transesterification reactions; mRNA processing; gene expression;
HNRNPH1	5	nucleoplasm; RNA splicing; mRNA splicing, via spliceosome; catalytic step 2 spliceosome; gene expression;
PCF11	5	nucleoplasm; RNA splicing; mRNA splicing, via spliceosome; mRNA processing; gene expression;
CPSF3	5	nucleoplasm; RNA splicing; mRNA splicing, via spliceosome; mRNA processing; gene expression;
SUGP1	5	nucleoplasm; RNA splicing; mRNA splicing, via spliceosome; spliceosomal complex; gene expression;
CPSF7	5	nucleoplasm; RNA splicing; mRNA splicing, via spliceosome; mRNA processing; gene expression;
SNRPA	5	nucleoplasm; RNA splicing; mRNA splicing, via spliceosome; spliceosomal complex; gene expression;
CLP1	5	nucleoplasm; RNA splicing; mRNA splicing, via spliceosome; mRNA processing; gene expression;
SNW1	5	nucleoplasm; mRNA splicing, via spliceosome; spliceosomal complex; catalytic step 2 spliceosome; gene expression;
NCBP1	5	nucleoplasm; RNA splicing; mRNA splicing, via spliceosome; mRNA processing; gene expression;
PHF5A	5	nucleoplasm; RNA splicing; U12-type spliceosomal complex; mRNA splicing, via spliceosome; gene expression;
SLU7	5	mRNA splicing, via spliceosome; spliceosomal complex; small nuclear ribonucleoprotein complex; catalytic step 2 spliceosome; RNA splicing, via transesterification reactions;

Genes shared at least 2 KEGG pathways with SF3B3 (count: 0)

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Region: chr16:70557691..70608820 View in gBrowse