ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

GO Report

Basic Info

ID	GO:0005681
Name	spliceosomal complex
Type	cellular component
No. of Genes in ADHDgene	43
Source	Pathway by PBA (with statistical significance of FDR<0.05)

PBA Result (with statistical significance of FDR<0.05)

Data Set Reference	Gene Set	Mapping Rule	P-value	FDR	Result Link
Neale BM, 2008	MsigDB 3.0 c5.cc	500kb upstream and downstream of gene	< 0.001	0.005	Link

GO related genes in ADHDgene (count: 43)

Literature-origin genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
PTBP2	polypyrimidine tract binding protein 2	1p21.3	1(0/1/0)	IEA
GEMIN2	gem (nuclear organelle) associated protein 2	14q21.1	1(1/0/0)	IEA

Genes from other sources (count: 41)

Approved Symbol	Approved Name	Source	Evidence[PMID]
SNRPD2	small nuclear ribonucleoprotein D2 polypeptide 16.5kDa	Mapped by PBA pathway	TAS[1701240]
U2AF2	U2 small nuclear RNA auxiliary factor 2	Mapped by PBA pathway	IDA[9731529]
HSPA8	heat shock 70kDa protein 8	Mapped by significant region	IEA
SCAF8	SR-related CTD-associated factor 8	Mapped by Literature SNP	IEA
SNRPN	small nuclear ribonucleoprotein polypeptide N	Mapped by CNV; Mapped by significant region; Mapped by PBA pathway	TAS[1533223]
CDC40	cell division cycle 40	Mapped by PBA pathway	TAS[9524131]
SNRPD3	small nuclear ribonucleoprotein D3 polypeptide 18kDa	Mapped by CNV; Mapped by PBA pathway	TAS[7527560]
U2AF1	U2 small nuclear RNA auxiliary factor 1	Mapped by PBA pathway	IDA[9731529]
HNRNPA2B1	heterogeneous nuclear ribonucleoprotein A2/B1	Mapped by CNV; Mapped by significant region; Mapped by PBA pathway	IDA[9731529]
SNRNP200	small nuclear ribonucleoprotein 200kDa (U5)	Mapped by LD-proxy	IDA[8670905]
SF3A1	splicing factor 3a, subunit 1, 120kDa	Mapped by PBA pathway	IDA[9731529]
PRPF18	pre-mRNA processing factor 18	Mapped by PBA pathway	IEA
API5	apoptosis inhibitor 5	Mapped by PBA pathway	ISS[11555636]
SNRPF	small nuclear ribonucleoprotein polypeptide F	Mapped by PBA pathway	IDA[7744013]
HNRNPA1L2	heterogeneous nuclear ribonucleoprotein A1-like 2	Mapped by LD-proxy	IEA
HNRNPA1	heterogeneous nuclear ribonucleoprotein A1	Mapped by PBA pathway	IDA[9731529]
SF3A2	splicing factor 3a, subunit 2, 66kDa	Mapped by PBA pathway	IDA[9731529]
SLU7	SLU7 splicing factor homolog (S. cerevisiae)	Mapped by significant region; Mapped by PBA pathway	IDA[10197984]
SF3B4	splicing factor 3b, subunit 4, 49kDa	Mapped by PBA pathway	IDA[9731529]
PRPF6	pre-mRNA processing factor 6	Mapped by PBA pathway	NAS[10788320]
SNRPB2	small nuclear ribonucleoprotein polypeptide B	Mapped by PBA pathway	IDA[9731529]
SF3B3	splicing factor 3b, subunit 3, 130kDa	Mapped by PBA pathway	TAS[10490618]
DHX8	DEAH (Asp-Glu-Ala-His) box polypeptide 8	Mapped by PBA pathway	TAS[7935475]
SNRPB	small nuclear ribonucleoprotein polypeptides B and B1	Mapped by PBA pathway	TAS[2531083]
PRPF4	pre-mRNA processing factor 4	Mapped by significant region	IC[9570313]; NAS[9328476]
PPIH	peptidylprolyl isomerase H (cyclophilin H)	Mapped by PBA pathway	IC[9570313]
SNRPA	small nuclear ribonucleoprotein polypeptide A	Mapped by PBA pathway	IDA[9731529]
SMNDC1	survival motor neuron domain containing 1	Mapped by PBA pathway	IEA
SNRPG	small nuclear ribonucleoprotein polypeptide G	Mapped by PBA pathway	TAS[7744013]
EFTUD2	elongation factor Tu GTP binding domain containing 2	Mapped by PBA pathway	TAS[9233818]
SNRPA1	small nuclear ribonucleoprotein polypeptide A'	Mapped by PBA pathway	IDA[9731529]
SF3A3	splicing factor 3a, subunit 3, 60kDa	Mapped by PBA pathway	IDA[9731529]
SF3B2	splicing factor 3b, subunit 2, 145kDa	Mapped by significant region; Mapped by PBA pathway	IDA[9731529]
SF1	splicing factor 1	Mapped by significant region; Mapped by PBA pathway	IDA[9731529]
HNRNPC	heterogeneous nuclear ribonucleoprotein C (C1/C2)	Mapped by PBA pathway	IDA[9731529]
IVNS1ABP	influenza virus NS1A binding protein	Mapped by significant region; Mapped by PBA pathway	TAS[9696811]
SUGP1	SURP and G patch domain containing 1	Mapped by LD-proxy	IEA
TXNL4A	thioredoxin-like 4A	Mapped by PBA pathway	TAS[10610776]
BCAS2	breast carcinoma amplified sequence 2	Mapped by PBA pathway	IDA[12169396]
CWC15	CWC15 spliceosome-associated protein homolog (S. cerevisiae)	Mapped by significant region	IDA
SNW1	SNW domain containing 1	Mapped by PBA pathway	IDA[15194481]