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- Data Summary
Gene Report
Approved Symbol | U2AF2 |
---|---|
Symbol Alias | U2AF65 |
Approved Name | U2 small nuclear RNA auxiliary factor 2 |
Previous Name | U2 (RNU2) small nuclear RNA auxiliary factor 2 |
Name Alias | U2 small nuclear ribonucleoprotein auxiliary factor (65kD), "splicing factor U2AF 65 kD subunit", "U2 snRNP auxiliary factor large subunit" |
Location | 19q13.43 |
Position | chr19:56165416-56186082, + |
External Links |
HGNC: 23156 Entrez Gene: 11338 Ensembl: ENSG00000063244 UCSC: uc002qlu.2 |
No. of Studies | 0 (significant: 0; non-significant: 0; trend: 0) |
Source | Mapped by PBA pathway |
GO terms by PBA (with statistical significance of FDR<0.05) (count: 1)
ID | Name | Type | Evidence[PMID] | No. of Genes in ADHDgene |
---|---|---|---|---|
GO:0005681 | spliceosomal complex | Cellular Component | IDA[9731529] | 51 |
GO terms by database search (count: 15)
ID | Name | Type | Evidence[PMID] | No. of Genes in ADHDgene |
---|---|---|---|---|
GO:0070742 | C2H2 zinc finger domain binding | Molecular Function | 2 | |
GO:0031124 | mRNA 3'-end processing | Biological Process | 8 | |
GO:0048025 | negative regulation of mRNA splicing, via spliceosome | Biological Process | IDA[15009664] | 2 |
GO:0010467 | gene expression | Biological Process | 140 | |
GO:0019899 | enzyme binding | Molecular Function | IPI[19574390] | 47 |
GO:0006406 | mRNA export from nucleus | Biological Process | 12 | |
GO:0008380 | RNA splicing | Biological Process | 65 | |
GO:0006369 | termination of RNA polymerase II transcription | Biological Process | 14 | |
GO:0006397 | mRNA processing | Biological Process | TAS[1538748] | 50 |
GO:0006366 | transcription from RNA polymerase II promoter | Biological Process | 62 | |
GO:0005654 | nucleoplasm | Cellular Component | 183 | |
GO:0005515 | protein binding | Molecular Function | 910 | |
GO:0003723 | RNA binding | Molecular Function | 104 | |
GO:0000398 | mRNA splicing, via spliceosome | Biological Process | IC[9731529] | 54 |
GO:0000166 | nucleotide binding | Molecular Function | 73 |
ID | Name | No. of Genes in ADHDgene | Brief Description |
---|---|---|---|
hsa03040 | Spliceosome | 47 | After transcription, eukaryotic mRNA precursors contain prot...... After transcription, eukaryotic mRNA precursors contain protein-coding exons and noncoding introns. In the following splicing, introns are excised and exons are joined by a macromolecular complex, the spliceosome. The standard spliceosome is made up of five small nuclear ribonucleoproteins (snRNPs), U1, U2, U4, U5, and U6 snRNPs, and several spliceosome-associated proteins (SAPs). Spliceosomes are not a simple stable complex, but a dynamic family of particles that assemble on the mRNA precursor and help fold it into a conformation that allows transesterification to proceed. Various spliceosome forms (e.g. A-, B- and C-complexes) have been identified. More... |
Region: chr19:56165416..56186082 View in gBrowse
Copyright: Bioinformatics Lab, Institute of Psychology, Chinese Academy of Sciences Feedback
Last update: Feb 26, 2014