ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	SNRPD3
Symbol Alias	SMD3, Sm-D3
Approved Name	small nuclear ribonucleoprotein D3 polypeptide 18kDa
Previous Name	"small nuclear ribonucleoprotein D3 polypeptide (18kD)"
Location	22q11.23
Position	chr22:24951471-25005947, 1
External Links	HGNC: 11160 Entrez Gene: 6634 Ensembl: ENSG00000100028 UCSC: uc003aam.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV; Mapped by PBA pathway

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Williams[2010]_37	chr22:22020325-23326630 (NCBI Build 36.1 (hg18))	1306306	22q11.23	Gain

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 20)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 1)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005681	spliceosomal complex	cellular component	TAS[7527560]	43

GO terms by database search (count: 19)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005683	U7 snRNP	cellular component	IDA[11574479]	5
GO:0005829	cytosol	cellular component	TAS	485
GO:0010467	gene expression	biological process	TAS	154
GO:0071208	histone pre-mRNA DCP binding	molecular function	ISS	2
GO:0000398	mRNA splicing, via spliceosome	biological process	IC[11991638]; TAS	58
GO:0006369	termination of RNA polymerase II transcription	biological process	TAS	15
GO:0000387	spliceosomal snRNP assembly	biological process	TAS	11
GO:0005654	nucleoplasm	cellular component	TAS	210
GO:0008380	RNA splicing	biological process	TAS	70
GO:0030532	small nuclear ribonucleoprotein complex	cellular component	TAS[1701240]	12
GO:0008334	histone mRNA metabolic process	biological process	TAS	6
GO:0016070	RNA metabolic process	biological process	TAS	54
GO:0005515	protein binding	molecular function	IPI	1015
GO:0006366	transcription from RNA polymerase II promoter	biological process	TAS	63
GO:0006397	mRNA processing	biological process	TAS	53
GO:0019899	enzyme binding	molecular function	IPI[17709427]	54
GO:0034660	ncRNA metabolic process	biological process	TAS	9
GO:0071013	catalytic step 2 spliceosome	cellular component	IDA[11991638]	33
GO:0005689	U12-type spliceosomal complex	cellular component	IDA[15146077]	17

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa05322	Systemic lupus erythematosus	20

Genes shared at least 5 GO terms with SNRPD3 (count: 60)

Gene Symbol	Pathway Count	Pathway List
SNRPB	19	U7 snRNP; cytosol; gene expression; histone pre-mRNA DCP binding; mRNA splicing, via spliceosome; termination of RNA polymerase II transcription; spliceosomal complex; spliceosomal snRNP assembly; nucleoplasm; RNA splicing; small nuclear ribonucleoprotein complex; histone mRNA metabolic process; RNA metabolic process; protein binding; transcription from RNA polymerase II promoter; mRNA processing; ncRNA metabolic process; catalytic step 2 spliceosome; U12-type spliceosomal complex;
SNRPG	18	U7 snRNP; cytosol; gene expression; mRNA splicing, via spliceosome; termination of RNA polymerase II transcription; spliceosomal complex; spliceosomal snRNP assembly; nucleoplasm; RNA splicing; small nuclear ribonucleoprotein complex; histone mRNA metabolic process; RNA metabolic process; protein binding; transcription from RNA polymerase II promoter; mRNA processing; ncRNA metabolic process; catalytic step 2 spliceosome; U12-type spliceosomal complex;
SNRPF	17	U7 snRNP; cytosol; gene expression; mRNA splicing, via spliceosome; termination of RNA polymerase II transcription; spliceosomal complex; spliceosomal snRNP assembly; nucleoplasm; RNA splicing; small nuclear ribonucleoprotein complex; histone mRNA metabolic process; RNA metabolic process; transcription from RNA polymerase II promoter; mRNA processing; ncRNA metabolic process; catalytic step 2 spliceosome; U12-type spliceosomal complex;
NCBP1	13	cytosol; gene expression; mRNA splicing, via spliceosome; termination of RNA polymerase II transcription; spliceosomal snRNP assembly; nucleoplasm; RNA splicing; histone mRNA metabolic process; RNA metabolic process; protein binding; transcription from RNA polymerase II promoter; mRNA processing; ncRNA metabolic process;
SNRPD2	13	cytosol; gene expression; mRNA splicing, via spliceosome; spliceosomal complex; spliceosomal snRNP assembly; nucleoplasm; RNA splicing; small nuclear ribonucleoprotein complex; RNA metabolic process; protein binding; ncRNA metabolic process; catalytic step 2 spliceosome; U12-type spliceosomal complex;
SNRPD1	12	cytosol; gene expression; mRNA splicing, via spliceosome; spliceosomal snRNP assembly; nucleoplasm; RNA splicing; small nuclear ribonucleoprotein complex; RNA metabolic process; protein binding; ncRNA metabolic process; catalytic step 2 spliceosome; U12-type spliceosomal complex;
GEMIN2	10	cytosol; gene expression; spliceosomal complex; spliceosomal snRNP assembly; nucleoplasm; RNA splicing; RNA metabolic process; protein binding; mRNA processing; ncRNA metabolic process;
U2AF2	10	gene expression; mRNA splicing, via spliceosome; termination of RNA polymerase II transcription; spliceosomal complex; nucleoplasm; RNA splicing; protein binding; transcription from RNA polymerase II promoter; mRNA processing; enzyme binding;
U2AF1	10	gene expression; mRNA splicing, via spliceosome; termination of RNA polymerase II transcription; spliceosomal complex; nucleoplasm; RNA splicing; protein binding; transcription from RNA polymerase II promoter; mRNA processing; catalytic step 2 spliceosome;
RNPS1	9	cytosol; gene expression; mRNA splicing, via spliceosome; termination of RNA polymerase II transcription; nucleoplasm; RNA splicing; RNA metabolic process; protein binding; transcription from RNA polymerase II promoter;
SF3B3	9	gene expression; mRNA splicing, via spliceosome; spliceosomal complex; nucleoplasm; RNA splicing; small nuclear ribonucleoprotein complex; mRNA processing; catalytic step 2 spliceosome; U12-type spliceosomal complex;
LSM11	8	U7 snRNP; gene expression; termination of RNA polymerase II transcription; nucleoplasm; histone mRNA metabolic process; protein binding; transcription from RNA polymerase II promoter; mRNA processing;
SF3A2	8	gene expression; mRNA splicing, via spliceosome; spliceosomal complex; nucleoplasm; RNA splicing; small nuclear ribonucleoprotein complex; mRNA processing; catalytic step 2 spliceosome;
HNRNPA2B1	8	gene expression; mRNA splicing, via spliceosome; spliceosomal complex; nucleoplasm; RNA splicing; protein binding; mRNA processing; catalytic step 2 spliceosome;
SF3A3	8	gene expression; mRNA splicing, via spliceosome; spliceosomal complex; nucleoplasm; RNA splicing; protein binding; mRNA processing; catalytic step 2 spliceosome;
SF3A1	8	gene expression; mRNA splicing, via spliceosome; spliceosomal complex; nucleoplasm; RNA splicing; protein binding; mRNA processing; catalytic step 2 spliceosome;
SNRPB2	8	gene expression; mRNA splicing, via spliceosome; spliceosomal complex; nucleoplasm; RNA splicing; protein binding; mRNA processing; catalytic step 2 spliceosome;
CDC40	8	gene expression; mRNA splicing, via spliceosome; termination of RNA polymerase II transcription; spliceosomal complex; nucleoplasm; RNA splicing; transcription from RNA polymerase II promoter; catalytic step 2 spliceosome;
CPSF3	8	gene expression; mRNA splicing, via spliceosome; termination of RNA polymerase II transcription; nucleoplasm; RNA splicing; protein binding; transcription from RNA polymerase II promoter; mRNA processing;
SNRPA1	8	gene expression; mRNA splicing, via spliceosome; spliceosomal complex; nucleoplasm; RNA splicing; small nuclear ribonucleoprotein complex; protein binding; catalytic step 2 spliceosome;
SF3B4	8	gene expression; mRNA splicing, via spliceosome; spliceosomal complex; nucleoplasm; RNA splicing; protein binding; mRNA processing; U12-type spliceosomal complex;
EFTUD2	8	gene expression; mRNA splicing, via spliceosome; spliceosomal complex; nucleoplasm; RNA splicing; protein binding; mRNA processing; catalytic step 2 spliceosome;
CPSF7	8	gene expression; mRNA splicing, via spliceosome; termination of RNA polymerase II transcription; nucleoplasm; RNA splicing; protein binding; transcription from RNA polymerase II promoter; mRNA processing;
SF3B2	8	gene expression; mRNA splicing, via spliceosome; spliceosomal complex; nucleoplasm; RNA splicing; mRNA processing; catalytic step 2 spliceosome; U12-type spliceosomal complex;
HSPA8	7	cytosol; gene expression; spliceosomal complex; RNA splicing; RNA metabolic process; protein binding; mRNA processing;
LSM4	7	cytosol; gene expression; RNA splicing; small nuclear ribonucleoprotein complex; RNA metabolic process; protein binding; mRNA processing;
CLP1	7	gene expression; mRNA splicing, via spliceosome; termination of RNA polymerase II transcription; nucleoplasm; RNA splicing; transcription from RNA polymerase II promoter; mRNA processing;
HNRNPC	7	gene expression; mRNA splicing, via spliceosome; spliceosomal complex; nucleoplasm; RNA splicing; protein binding; catalytic step 2 spliceosome;
SNRNP200	7	gene expression; mRNA splicing, via spliceosome; spliceosomal complex; nucleoplasm; RNA splicing; protein binding; catalytic step 2 spliceosome;
PCF11	7	gene expression; mRNA splicing, via spliceosome; termination of RNA polymerase II transcription; nucleoplasm; RNA splicing; transcription from RNA polymerase II promoter; mRNA processing;
PRPF6	7	gene expression; mRNA splicing, via spliceosome; spliceosomal complex; nucleoplasm; RNA splicing; protein binding; catalytic step 2 spliceosome;
HNRNPA1	7	gene expression; mRNA splicing, via spliceosome; spliceosomal complex; nucleoplasm; RNA splicing; mRNA processing; catalytic step 2 spliceosome;
PRPF8	7	gene expression; mRNA splicing, via spliceosome; nucleoplasm; RNA splicing; protein binding; mRNA processing; catalytic step 2 spliceosome;
SART1	6	cytosol; mRNA splicing, via spliceosome; spliceosomal snRNP assembly; nucleoplasm; protein binding; catalytic step 2 spliceosome;
CLNS1A	6	cytosol; gene expression; spliceosomal snRNP assembly; RNA metabolic process; protein binding; ncRNA metabolic process;
HNRNPH1	6	gene expression; mRNA splicing, via spliceosome; nucleoplasm; RNA splicing; protein binding; catalytic step 2 spliceosome;
SNRPA	6	gene expression; mRNA splicing, via spliceosome; spliceosomal complex; nucleoplasm; RNA splicing; protein binding;
PRPF4	6	gene expression; mRNA splicing, via spliceosome; spliceosomal complex; nucleoplasm; RNA splicing; protein binding;
TXNL4A	6	gene expression; mRNA splicing, via spliceosome; spliceosomal complex; nucleoplasm; RNA splicing; protein binding;
DDX23	6	gene expression; mRNA splicing, via spliceosome; nucleoplasm; RNA splicing; protein binding; catalytic step 2 spliceosome;
SNW1	6	gene expression; mRNA splicing, via spliceosome; spliceosomal complex; nucleoplasm; protein binding; catalytic step 2 spliceosome;
UBC	5	cytosol; gene expression; nucleoplasm; RNA metabolic process; protein binding;
PSMD5	5	cytosol; gene expression; nucleoplasm; RNA metabolic process; protein binding;
TCEB1	5	cytosol; gene expression; nucleoplasm; protein binding; transcription from RNA polymerase II promoter;
XPO1	5	cytosol; gene expression; nucleoplasm; RNA metabolic process; protein binding;
PSMD7	5	cytosol; gene expression; nucleoplasm; RNA metabolic process; protein binding;
TCEB2	5	cytosol; gene expression; nucleoplasm; protein binding; transcription from RNA polymerase II promoter;
UBB	5	cytosol; gene expression; nucleoplasm; RNA metabolic process; protein binding;
RPS2	5	cytosol; gene expression; nucleoplasm; RNA metabolic process; protein binding;
PSMC3	5	cytosol; gene expression; nucleoplasm; RNA metabolic process; protein binding;
PSMB7	5	cytosol; gene expression; nucleoplasm; RNA metabolic process; protein binding;
DHX9	5	gene expression; mRNA splicing, via spliceosome; nucleoplasm; RNA splicing; protein binding;
TAF10	5	gene expression; nucleoplasm; protein binding; transcription from RNA polymerase II promoter; enzyme binding;
PHF5A	5	gene expression; mRNA splicing, via spliceosome; nucleoplasm; RNA splicing; U12-type spliceosomal complex;
SUGP1	5	gene expression; mRNA splicing, via spliceosome; spliceosomal complex; nucleoplasm; RNA splicing;
POLR2G	5	gene expression; mRNA splicing, via spliceosome; nucleoplasm; RNA splicing; transcription from RNA polymerase II promoter;
CD2BP2	5	gene expression; mRNA splicing, via spliceosome; nucleoplasm; RNA splicing; protein binding;
FUS	5	gene expression; mRNA splicing, via spliceosome; nucleoplasm; RNA splicing; protein binding;
SMC1A	5	gene expression; mRNA splicing, via spliceosome; nucleoplasm; RNA splicing; protein binding;
DHX8	5	mRNA splicing, via spliceosome; spliceosomal complex; RNA splicing; protein binding; catalytic step 2 spliceosome;

Genes shared at least 2 KEGG pathways with SNRPD3 (count: 0)

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Region: chr22:24951471..25005947 View in gBrowse