ADHDgene Database

Hot Results

Quick Search

Keyword:
Type:

Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	SNRPD2
Previous Symbol	SNRPD1
Symbol Alias	Sm-D2
Approved Name	small nuclear ribonucleoprotein D2 polypeptide 16.5kDa
Previous Name	small nuclear ribonucleoprotein D2 polypeptide (16.5kD)
Name Alias	snRNP core protein D2
Location	19q13.2-q13.3
Position	chr19:46190712-46195443, -
External Links	HGNC: 11159 Entrez Gene: 6633 Ensembl: ENSG00000125743 UCSC: uc002pcw.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by PBA pathway

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 14)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 1)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005681	spliceosomal complex	Cellular Component	TAS[1701240]	51

GO terms by database search (count: 13)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0034660	ncRNA metabolic process	Biological Process		8
GO:0071013	catalytic step 2 spliceosome	Cellular Component	IDA[11991638]	31
GO:0005829	cytosol	Cellular Component		447
GO:0005689	U12-type spliceosomal complex	Cellular Component	IDA[15146077]	16
GO:0005654	nucleoplasm	Cellular Component		183
GO:0030532	small nuclear ribonucleoprotein complex	Cellular Component	TAS[1701240]	12
GO:0016070	RNA metabolic process	Biological Process		46
GO:0010467	gene expression	Biological Process		140
GO:0008380	RNA splicing	Biological Process		65
GO:0005515	protein binding	Molecular Function	IPI[11748230]	910
GO:0000398	mRNA splicing, via spliceosome	Biological Process	IC[11991638]	54
GO:0000387	spliceosomal snRNP assembly	Biological Process		10
GO:0000245	spliceosomal complex assembly	Biological Process	TAS[7527560]	8

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa03040	Spliceosome	47	After transcription, eukaryotic mRNA precursors contain prot...... After transcription, eukaryotic mRNA precursors contain protein-coding exons and noncoding introns. In the following splicing, introns are excised and exons are joined by a macromolecular complex, the spliceosome. The standard spliceosome is made up of five small nuclear ribonucleoproteins (snRNPs), U1, U2, U4, U5, and U6 snRNPs, and several spliceosome-associated proteins (SAPs). Spliceosomes are not a simple stable complex, but a dynamic family of particles that assemble on the mRNA precursor and help fold it into a conformation that allows transesterification to proceed. Various spliceosome forms (e.g. A-, B- and C-complexes) have been identified. More...

Genes shared at least 5 GO terms with SNRPD2 (count: 50)

Gene Symbol	Pathway Count	Pathway List
SNRPG	14	ncRNA metabolic process; catalytic step 2 spliceosome; cytosol; U12-type spliceosomal complex; spliceosomal complex; nucleoplasm; small nuclear ribonucleoprotein complex; RNA metabolic process; gene expression; RNA splicing; protein binding; mRNA splicing, via spliceosome; spliceosomal snRNP assembly; spliceosomal complex assembly;
SNRPB	13	ncRNA metabolic process; catalytic step 2 spliceosome; cytosol; U12-type spliceosomal complex; spliceosomal complex; nucleoplasm; small nuclear ribonucleoprotein complex; RNA metabolic process; gene expression; RNA splicing; protein binding; mRNA splicing, via spliceosome; spliceosomal snRNP assembly;
SNRPD1	13	ncRNA metabolic process; catalytic step 2 spliceosome; cytosol; U12-type spliceosomal complex; nucleoplasm; small nuclear ribonucleoprotein complex; RNA metabolic process; gene expression; RNA splicing; protein binding; mRNA splicing, via spliceosome; spliceosomal snRNP assembly; spliceosomal complex assembly;
SNRPD3	13	ncRNA metabolic process; catalytic step 2 spliceosome; cytosol; U12-type spliceosomal complex; spliceosomal complex; nucleoplasm; small nuclear ribonucleoprotein complex; RNA metabolic process; gene expression; RNA splicing; protein binding; mRNA splicing, via spliceosome; spliceosomal snRNP assembly;
SNRPF	12	ncRNA metabolic process; catalytic step 2 spliceosome; cytosol; U12-type spliceosomal complex; spliceosomal complex; nucleoplasm; small nuclear ribonucleoprotein complex; RNA metabolic process; gene expression; RNA splicing; mRNA splicing, via spliceosome; spliceosomal snRNP assembly;
NCBP1	9	ncRNA metabolic process; cytosol; nucleoplasm; RNA metabolic process; gene expression; RNA splicing; protein binding; mRNA splicing, via spliceosome; spliceosomal snRNP assembly;
PRPF6	8	catalytic step 2 spliceosome; spliceosomal complex; nucleoplasm; gene expression; RNA splicing; protein binding; mRNA splicing, via spliceosome; spliceosomal complex assembly;
SF3B3	8	catalytic step 2 spliceosome; U12-type spliceosomal complex; spliceosomal complex; nucleoplasm; small nuclear ribonucleoprotein complex; gene expression; RNA splicing; mRNA splicing, via spliceosome;
SNRPA1	8	catalytic step 2 spliceosome; spliceosomal complex; nucleoplasm; small nuclear ribonucleoprotein complex; gene expression; RNA splicing; protein binding; mRNA splicing, via spliceosome;
DDX23	7	catalytic step 2 spliceosome; spliceosomal complex; nucleoplasm; gene expression; RNA splicing; protein binding; mRNA splicing, via spliceosome;
EFTUD2	7	catalytic step 2 spliceosome; spliceosomal complex; nucleoplasm; gene expression; RNA splicing; protein binding; mRNA splicing, via spliceosome;
HNRNPA2B1	7	catalytic step 2 spliceosome; spliceosomal complex; nucleoplasm; gene expression; RNA splicing; protein binding; mRNA splicing, via spliceosome;
HNRNPC	7	catalytic step 2 spliceosome; spliceosomal complex; nucleoplasm; gene expression; RNA splicing; protein binding; mRNA splicing, via spliceosome;
PRPF8	7	catalytic step 2 spliceosome; spliceosomal complex; nucleoplasm; gene expression; RNA splicing; protein binding; mRNA splicing, via spliceosome;
SF3A1	7	catalytic step 2 spliceosome; spliceosomal complex; nucleoplasm; gene expression; RNA splicing; protein binding; mRNA splicing, via spliceosome;
SF3A2	7	catalytic step 2 spliceosome; spliceosomal complex; nucleoplasm; small nuclear ribonucleoprotein complex; gene expression; RNA splicing; mRNA splicing, via spliceosome;
SF3A3	7	catalytic step 2 spliceosome; spliceosomal complex; nucleoplasm; gene expression; RNA splicing; protein binding; mRNA splicing, via spliceosome;
SF3B2	7	catalytic step 2 spliceosome; U12-type spliceosomal complex; spliceosomal complex; nucleoplasm; gene expression; RNA splicing; mRNA splicing, via spliceosome;
SNRNP200	7	catalytic step 2 spliceosome; spliceosomal complex; nucleoplasm; gene expression; RNA splicing; protein binding; mRNA splicing, via spliceosome;
SNRPB2	7	catalytic step 2 spliceosome; spliceosomal complex; nucleoplasm; gene expression; RNA splicing; protein binding; mRNA splicing, via spliceosome;
U2AF1	7	catalytic step 2 spliceosome; spliceosomal complex; nucleoplasm; gene expression; RNA splicing; protein binding; mRNA splicing, via spliceosome;
LSM4	7	cytosol; spliceosomal complex; small nuclear ribonucleoprotein complex; RNA metabolic process; gene expression; RNA splicing; protein binding;
SF3B4	7	U12-type spliceosomal complex; spliceosomal complex; nucleoplasm; gene expression; RNA splicing; protein binding; mRNA splicing, via spliceosome;
TXNL4A	7	spliceosomal complex; nucleoplasm; gene expression; RNA splicing; protein binding; mRNA splicing, via spliceosome; spliceosomal complex assembly;
CLNS1A	6	ncRNA metabolic process; cytosol; RNA metabolic process; gene expression; protein binding; spliceosomal snRNP assembly;
CDC40	6	catalytic step 2 spliceosome; spliceosomal complex; nucleoplasm; gene expression; RNA splicing; mRNA splicing, via spliceosome;
HNRNPA1	6	catalytic step 2 spliceosome; spliceosomal complex; nucleoplasm; gene expression; RNA splicing; mRNA splicing, via spliceosome;
HNRNPH1	6	catalytic step 2 spliceosome; nucleoplasm; gene expression; RNA splicing; protein binding; mRNA splicing, via spliceosome;
SART1	6	catalytic step 2 spliceosome; cytosol; nucleoplasm; protein binding; mRNA splicing, via spliceosome; spliceosomal snRNP assembly;
SNW1	6	catalytic step 2 spliceosome; spliceosomal complex; nucleoplasm; gene expression; protein binding; mRNA splicing, via spliceosome;
HSPA8	6	cytosol; spliceosomal complex; RNA metabolic process; gene expression; RNA splicing; protein binding;
PHF5A	6	U12-type spliceosomal complex; spliceosomal complex; nucleoplasm; gene expression; RNA splicing; mRNA splicing, via spliceosome;
ZRSR2	6	U12-type spliceosomal complex; spliceosomal complex; RNA splicing; protein binding; mRNA splicing, via spliceosome; spliceosomal complex assembly;
PRPF4	6	spliceosomal complex; nucleoplasm; gene expression; RNA splicing; protein binding; mRNA splicing, via spliceosome;
SNRPA	6	spliceosomal complex; nucleoplasm; gene expression; RNA splicing; protein binding; mRNA splicing, via spliceosome;
U2AF2	6	spliceosomal complex; nucleoplasm; gene expression; RNA splicing; protein binding; mRNA splicing, via spliceosome;
DHX8	5	catalytic step 2 spliceosome; spliceosomal complex; RNA splicing; protein binding; mRNA splicing, via spliceosome;
PSMB7	5	cytosol; nucleoplasm; RNA metabolic process; gene expression; protein binding;
PSMC3	5	cytosol; nucleoplasm; RNA metabolic process; gene expression; protein binding;
PSMD5	5	cytosol; nucleoplasm; RNA metabolic process; gene expression; protein binding;
PSMD7	5	cytosol; nucleoplasm; RNA metabolic process; gene expression; protein binding;
UBB	5	cytosol; nucleoplasm; RNA metabolic process; gene expression; protein binding;
UBC	5	cytosol; nucleoplasm; RNA metabolic process; gene expression; protein binding;
XPO1	5	cytosol; nucleoplasm; RNA metabolic process; gene expression; protein binding;
CD2BP2	5	nucleoplasm; gene expression; RNA splicing; protein binding; mRNA splicing, via spliceosome;
CPSF3	5	nucleoplasm; gene expression; RNA splicing; protein binding; mRNA splicing, via spliceosome;
CPSF7	5	nucleoplasm; gene expression; RNA splicing; protein binding; mRNA splicing, via spliceosome;
DHX9	5	nucleoplasm; gene expression; RNA splicing; protein binding; mRNA splicing, via spliceosome;
FUS	5	nucleoplasm; gene expression; RNA splicing; protein binding; mRNA splicing, via spliceosome;
SMC1A	5	nucleoplasm; gene expression; RNA splicing; protein binding; mRNA splicing, via spliceosome;

Genes shared at least 2 KEGG pathways with SNRPD2 (count: 0)

View in gBrowse

Region: chr19:46190712..46195443 View in gBrowse