ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	SNRPA
Symbol Alias	U1A, U1-A, Mud1
Approved Name	small nuclear ribonucleoprotein polypeptide A
Location	19q13.1
Position	chr19:41256759-41271297, +
External Links	HGNC: 11151 Entrez Gene: 6626 Ensembl: ENSG00000077312 UCSC: uc002ooz.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by PBA pathway

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 9)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 1)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005681	spliceosomal complex	Cellular Component	IDA[9731529]	51

GO terms by database search (count: 8)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005515	protein binding	Molecular Function	IPI[9848648]	910
GO:0005654	nucleoplasm	Cellular Component		183
GO:0008380	RNA splicing	Biological Process		65
GO:0000166	nucleotide binding	Molecular Function		73
GO:0000398	mRNA splicing, via spliceosome	Biological Process	IC[9731529]	54
GO:0003723	RNA binding	Molecular Function	IDA[19561594]	104
GO:0017069	snRNA binding	Molecular Function		2
GO:0010467	gene expression	Biological Process		140

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa03040	Spliceosome	47	After transcription, eukaryotic mRNA precursors contain prot...... After transcription, eukaryotic mRNA precursors contain protein-coding exons and noncoding introns. In the following splicing, introns are excised and exons are joined by a macromolecular complex, the spliceosome. The standard spliceosome is made up of five small nuclear ribonucleoproteins (snRNPs), U1, U2, U4, U5, and U6 snRNPs, and several spliceosome-associated proteins (SAPs). Spliceosomes are not a simple stable complex, but a dynamic family of particles that assemble on the mRNA precursor and help fold it into a conformation that allows transesterification to proceed. Various spliceosome forms (e.g. A-, B- and C-complexes) have been identified. More...

Genes shared at least 5 GO terms with SNRPA (count: 43)

Gene Symbol	Pathway Count	Pathway List
HNRNPA2B1	8	protein binding; nucleoplasm; spliceosomal complex; RNA splicing; nucleotide binding; mRNA splicing, via spliceosome; RNA binding; gene expression;
HNRNPC	8	protein binding; nucleoplasm; spliceosomal complex; RNA splicing; nucleotide binding; mRNA splicing, via spliceosome; RNA binding; gene expression;
SF3B4	8	protein binding; nucleoplasm; spliceosomal complex; RNA splicing; nucleotide binding; mRNA splicing, via spliceosome; RNA binding; gene expression;
SNRPB2	8	protein binding; nucleoplasm; spliceosomal complex; RNA splicing; nucleotide binding; mRNA splicing, via spliceosome; snRNA binding; gene expression;
U2AF1	8	protein binding; nucleoplasm; spliceosomal complex; RNA splicing; nucleotide binding; mRNA splicing, via spliceosome; RNA binding; gene expression;
U2AF2	8	protein binding; nucleoplasm; spliceosomal complex; RNA splicing; nucleotide binding; mRNA splicing, via spliceosome; RNA binding; gene expression;
CPSF7	7	protein binding; nucleoplasm; RNA splicing; nucleotide binding; mRNA splicing, via spliceosome; RNA binding; gene expression;
FUS	7	protein binding; nucleoplasm; RNA splicing; nucleotide binding; mRNA splicing, via spliceosome; RNA binding; gene expression;
HNRNPH1	7	protein binding; nucleoplasm; RNA splicing; nucleotide binding; mRNA splicing, via spliceosome; RNA binding; gene expression;
PRPF6	7	protein binding; nucleoplasm; spliceosomal complex; RNA splicing; mRNA splicing, via spliceosome; RNA binding; gene expression;
PRPF8	7	protein binding; nucleoplasm; spliceosomal complex; RNA splicing; mRNA splicing, via spliceosome; RNA binding; gene expression;
SF3A1	7	protein binding; nucleoplasm; spliceosomal complex; RNA splicing; mRNA splicing, via spliceosome; RNA binding; gene expression;
SNRPA1	7	protein binding; nucleoplasm; spliceosomal complex; RNA splicing; mRNA splicing, via spliceosome; RNA binding; gene expression;
SNRPG	7	protein binding; nucleoplasm; spliceosomal complex; RNA splicing; mRNA splicing, via spliceosome; RNA binding; gene expression;
HNRNPA1	7	nucleoplasm; spliceosomal complex; RNA splicing; nucleotide binding; mRNA splicing, via spliceosome; RNA binding; gene expression;
CPSF3	6	protein binding; nucleoplasm; RNA splicing; mRNA splicing, via spliceosome; RNA binding; gene expression;
DDX23	6	protein binding; nucleoplasm; spliceosomal complex; RNA splicing; mRNA splicing, via spliceosome; gene expression;
EFTUD2	6	protein binding; nucleoplasm; spliceosomal complex; RNA splicing; mRNA splicing, via spliceosome; gene expression;
NCBP1	6	protein binding; nucleoplasm; RNA splicing; mRNA splicing, via spliceosome; RNA binding; gene expression;
PRPF4	6	protein binding; nucleoplasm; spliceosomal complex; RNA splicing; mRNA splicing, via spliceosome; gene expression;
SF3A3	6	protein binding; nucleoplasm; spliceosomal complex; RNA splicing; mRNA splicing, via spliceosome; gene expression;
SNRNP200	6	protein binding; nucleoplasm; spliceosomal complex; RNA splicing; mRNA splicing, via spliceosome; gene expression;
SNRPB	6	protein binding; nucleoplasm; spliceosomal complex; RNA splicing; mRNA splicing, via spliceosome; gene expression;
SNRPD1	6	protein binding; nucleoplasm; RNA splicing; mRNA splicing, via spliceosome; RNA binding; gene expression;
SNRPD2	6	protein binding; nucleoplasm; spliceosomal complex; RNA splicing; mRNA splicing, via spliceosome; gene expression;
SNRPD3	6	protein binding; nucleoplasm; spliceosomal complex; RNA splicing; mRNA splicing, via spliceosome; gene expression;
TXNL4A	6	protein binding; nucleoplasm; spliceosomal complex; RNA splicing; mRNA splicing, via spliceosome; gene expression;
SNRPF	6	nucleoplasm; spliceosomal complex; RNA splicing; mRNA splicing, via spliceosome; RNA binding; gene expression;
CD2BP2	5	protein binding; nucleoplasm; RNA splicing; mRNA splicing, via spliceosome; gene expression;
DHX8	5	protein binding; spliceosomal complex; RNA splicing; mRNA splicing, via spliceosome; RNA binding;
DHX9	5	protein binding; nucleoplasm; RNA splicing; mRNA splicing, via spliceosome; gene expression;
LSM4	5	protein binding; spliceosomal complex; RNA splicing; RNA binding; gene expression;
RBM4	5	protein binding; nucleoplasm; RNA splicing; nucleotide binding; RNA binding;
SMC1A	5	protein binding; nucleoplasm; RNA splicing; mRNA splicing, via spliceosome; gene expression;
SNW1	5	protein binding; nucleoplasm; spliceosomal complex; mRNA splicing, via spliceosome; gene expression;
ZRSR2	5	protein binding; spliceosomal complex; RNA splicing; nucleotide binding; mRNA splicing, via spliceosome;
CDC40	5	nucleoplasm; spliceosomal complex; RNA splicing; mRNA splicing, via spliceosome; gene expression;
PHF5A	5	nucleoplasm; spliceosomal complex; RNA splicing; mRNA splicing, via spliceosome; gene expression;
POLR2G	5	nucleoplasm; RNA splicing; mRNA splicing, via spliceosome; RNA binding; gene expression;
SF3A2	5	nucleoplasm; spliceosomal complex; RNA splicing; mRNA splicing, via spliceosome; gene expression;
SF3B2	5	nucleoplasm; spliceosomal complex; RNA splicing; mRNA splicing, via spliceosome; gene expression;
SF3B3	5	nucleoplasm; spliceosomal complex; RNA splicing; mRNA splicing, via spliceosome; gene expression;
ZCRB1	5	nucleoplasm; spliceosomal complex; RNA splicing; nucleotide binding; RNA binding;

Genes shared at least 2 KEGG pathways with SNRPA (count: 0)

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Region: chr19:41256759..41271297 View in gBrowse