ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	CD2BP2
Symbol Alias	LIN1, Snu40
Approved Name	CD2 (cytoplasmic tail) binding protein 2
Previous Name	CD2 antigen (cytoplasmic tail)-binding protein 2
Location	16p11.2
Position	chr16:30362087-30366682, -
External Links	HGNC: 1656 Entrez Gene: 10421 Ensembl: ENSG00000169217 UCSC: uc002dxs.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 3)

ID	Location	Size	Band	Type	Inheritance
CNV_Williams[2010]_16	chr16:29563594-30367556 (NCBI Build 36.1 (hg18))	803963	16p11.2	Loss
CNV_Williams[2010]_34	chr16:29342178-31155425 (NCBI Build 36.1 (hg18))	1813248	16p11.2	Loss	De novo
CNV_Williams[2010]_39	chr16:29342178-31155425 (NCBI Build 36.1 (hg18))	1813247	16p11.2	Gain

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 13)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 13)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0016607	nuclear speck	Cellular Component	IDA[15840814]	34
GO:0043021	ribonucleoprotein complex binding	Molecular Function	IDA[15840814]	4
GO:0010467	gene expression	Biological Process		140
GO:0010923	negative regulation of phosphatase activity	Biological Process	IDA[19389623]	8
GO:0046540	U4/U6 x U5 tri-snRNP complex	Cellular Component	IDA[15840814]	3
GO:0005515	protein binding	Molecular Function	IPI[15840814]	910
GO:0005634	nucleus	Cellular Component	IDA[15840814]	770
GO:0000244	assembly of spliceosomal tri-snRNP	Biological Process	NAS[15840814]	2
GO:0000398	mRNA splicing, via spliceosome	Biological Process		54
GO:0005737	cytoplasm	Cellular Component		690
GO:0008380	RNA splicing	Biological Process		65
GO:0005654	nucleoplasm	Cellular Component	IDA[15840814]	183
GO:0005682	U5 snRNP	Cellular Component	IDA[15840814]	5

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with CD2BP2 (count: 52)

Gene Symbol	Pathway Count	Pathway List
PRPF6	11	nuclear speck; ribonucleoprotein complex binding; gene expression; U4/U6 x U5 tri-snRNP complex; protein binding; nucleus; assembly of spliceosomal tri-snRNP; mRNA splicing, via spliceosome; RNA splicing; nucleoplasm; U5 snRNP;
EFTUD2	8	nuclear speck; gene expression; protein binding; nucleus; mRNA splicing, via spliceosome; cytoplasm; RNA splicing; nucleoplasm;
PRPF4	7	nuclear speck; gene expression; protein binding; nucleus; mRNA splicing, via spliceosome; RNA splicing; nucleoplasm;
PRPF8	7	nuclear speck; gene expression; protein binding; mRNA splicing, via spliceosome; RNA splicing; nucleoplasm; U5 snRNP;
SF3A3	7	nuclear speck; gene expression; protein binding; nucleus; mRNA splicing, via spliceosome; RNA splicing; nucleoplasm;
U2AF1	7	nuclear speck; gene expression; protein binding; nucleus; mRNA splicing, via spliceosome; RNA splicing; nucleoplasm;
DDX23	7	gene expression; protein binding; nucleus; mRNA splicing, via spliceosome; RNA splicing; nucleoplasm; U5 snRNP;
DHX9	7	gene expression; protein binding; nucleus; mRNA splicing, via spliceosome; cytoplasm; RNA splicing; nucleoplasm;
FUS	7	gene expression; protein binding; nucleus; mRNA splicing, via spliceosome; cytoplasm; RNA splicing; nucleoplasm;
HNRNPA2B1	7	gene expression; protein binding; nucleus; mRNA splicing, via spliceosome; cytoplasm; RNA splicing; nucleoplasm;
HNRNPH1	7	gene expression; protein binding; nucleus; mRNA splicing, via spliceosome; cytoplasm; RNA splicing; nucleoplasm;
SMC1A	7	gene expression; protein binding; nucleus; mRNA splicing, via spliceosome; cytoplasm; RNA splicing; nucleoplasm;
SNRNP200	7	gene expression; protein binding; nucleus; mRNA splicing, via spliceosome; RNA splicing; nucleoplasm; U5 snRNP;
PPIH	6	nuclear speck; ribonucleoprotein complex binding; U4/U6 x U5 tri-snRNP complex; protein binding; mRNA splicing, via spliceosome; cytoplasm;
RBM4	6	nuclear speck; protein binding; nucleus; cytoplasm; RNA splicing; nucleoplasm;
CPSF7	6	gene expression; protein binding; nucleus; mRNA splicing, via spliceosome; RNA splicing; nucleoplasm;
HNRNPA1	6	gene expression; nucleus; mRNA splicing, via spliceosome; cytoplasm; RNA splicing; nucleoplasm;
NCBP1	6	gene expression; protein binding; nucleus; mRNA splicing, via spliceosome; RNA splicing; nucleoplasm;
SF3A1	6	gene expression; protein binding; nucleus; mRNA splicing, via spliceosome; RNA splicing; nucleoplasm;
SNRPD1	6	gene expression; protein binding; nucleus; mRNA splicing, via spliceosome; RNA splicing; nucleoplasm;
MAML1	5	nuclear speck; gene expression; protein binding; nucleus; nucleoplasm;
PHF5A	5	nuclear speck; gene expression; mRNA splicing, via spliceosome; RNA splicing; nucleoplasm;
PRPF19	5	nuclear speck; protein binding; nucleus; mRNA splicing, via spliceosome; cytoplasm;
RFWD2	5	nuclear speck; protein binding; nucleus; cytoplasm; nucleoplasm;
SMNDC1	5	nuclear speck; protein binding; nucleus; cytoplasm; RNA splicing;
CPSF3	5	gene expression; protein binding; mRNA splicing, via spliceosome; RNA splicing; nucleoplasm;
DGCR8	5	gene expression; protein binding; nucleus; cytoplasm; nucleoplasm;
HNRNPC	5	gene expression; protein binding; mRNA splicing, via spliceosome; RNA splicing; nucleoplasm;
MEN1	5	gene expression; protein binding; nucleus; cytoplasm; nucleoplasm;
NCOR1	5	gene expression; protein binding; nucleus; cytoplasm; nucleoplasm;
NEDD4L	5	gene expression; protein binding; nucleus; cytoplasm; nucleoplasm;
NR4A2	5	gene expression; protein binding; nucleus; cytoplasm; nucleoplasm;
PGR	5	gene expression; protein binding; nucleus; cytoplasm; nucleoplasm;
POLR2G	5	gene expression; nucleus; mRNA splicing, via spliceosome; RNA splicing; nucleoplasm;
PSMC3	5	gene expression; protein binding; nucleus; cytoplasm; nucleoplasm;
RBPJ	5	gene expression; protein binding; nucleus; cytoplasm; nucleoplasm;
SF3B2	5	gene expression; nucleus; mRNA splicing, via spliceosome; RNA splicing; nucleoplasm;
SF3B4	5	gene expression; protein binding; mRNA splicing, via spliceosome; RNA splicing; nucleoplasm;
SNRPA	5	gene expression; protein binding; mRNA splicing, via spliceosome; RNA splicing; nucleoplasm;
SNRPA1	5	gene expression; protein binding; mRNA splicing, via spliceosome; RNA splicing; nucleoplasm;
SNRPB	5	gene expression; protein binding; mRNA splicing, via spliceosome; RNA splicing; nucleoplasm;
SNRPB2	5	gene expression; protein binding; mRNA splicing, via spliceosome; RNA splicing; nucleoplasm;
SNRPD2	5	gene expression; protein binding; mRNA splicing, via spliceosome; RNA splicing; nucleoplasm;
SNRPD3	5	gene expression; protein binding; mRNA splicing, via spliceosome; RNA splicing; nucleoplasm;
SNRPG	5	gene expression; protein binding; mRNA splicing, via spliceosome; RNA splicing; nucleoplasm;
SNW1	5	gene expression; protein binding; nucleus; mRNA splicing, via spliceosome; nucleoplasm;
SSRP1	5	gene expression; protein binding; nucleus; cytoplasm; nucleoplasm;
TAF10	5	gene expression; protein binding; nucleus; cytoplasm; nucleoplasm;
TXNL4A	5	gene expression; protein binding; mRNA splicing, via spliceosome; RNA splicing; nucleoplasm;
U2AF2	5	gene expression; protein binding; mRNA splicing, via spliceosome; RNA splicing; nucleoplasm;
YAP1	5	gene expression; protein binding; nucleus; cytoplasm; nucleoplasm;
SART1	5	protein binding; nucleus; mRNA splicing, via spliceosome; cytoplasm; nucleoplasm;

Genes shared at least 2 KEGG pathways with CD2BP2 (count: 0)

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Region: chr16:30362087..30366682 View in gBrowse