ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	HNRNPA1
Previous Symbol	HNRPA1
Symbol Alias	hnRNPA1, hnRNP-A1
Approved Name	heterogeneous nuclear ribonucleoprotein A1
Location	12q13.1
Position	chr12:54674488-54679030, +
External Links	HGNC: 5031 Entrez Gene: 3178 Ensembl: ENSG00000135486 UCSC: uc001sfl.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by PBA pathway

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 21)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 1)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005681	spliceosomal complex	Cellular Component	IDA[9731529]	51

GO terms by database search (count: 20)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005737	cytoplasm	Cellular Component		690
GO:0005730	nucleolus	Cellular Component		243
GO:0005654	nucleoplasm	Cellular Component	IDA[8521471]	183
GO:0010467	gene expression	Biological Process		140
GO:0008380	RNA splicing	Biological Process		65
GO:0006405	RNA export from nucleus	Biological Process	IC[8521471]	2
GO:0006397	mRNA processing	Biological Process	TAS[8521471]	50
GO:0000398	mRNA splicing, via spliceosome	Biological Process	IC[9731529]	54
GO:0000166	nucleotide binding	Molecular Function		73
GO:0005634	nucleus	Cellular Component		770
GO:0003727	single-stranded RNA binding	Molecular Function	IC[8521471]	3
GO:0003723	RNA binding	Molecular Function	TAS[8521471]	104
GO:0003697	single-stranded DNA binding	Molecular Function	IDA[8521471]	5
GO:0045111	intermediate filament cytoskeleton	Cellular Component		5
GO:0051028	mRNA transport	Biological Process		8
GO:0019048	virus-host interaction	Biological Process		54
GO:0030529	ribonucleoprotein complex	Cellular Component	IDA[18809582]	23
GO:0071013	catalytic step 2 spliceosome	Cellular Component	IDA[11991638]	31
GO:0051168	nuclear export	Biological Process	IDA[8521471]	3
GO:0051170	nuclear import	Biological Process	IDA[8521471]	1

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa03040	Spliceosome	47	After transcription, eukaryotic mRNA precursors contain prot...... After transcription, eukaryotic mRNA precursors contain protein-coding exons and noncoding introns. In the following splicing, introns are excised and exons are joined by a macromolecular complex, the spliceosome. The standard spliceosome is made up of five small nuclear ribonucleoproteins (snRNPs), U1, U2, U4, U5, and U6 snRNPs, and several spliceosome-associated proteins (SAPs). Spliceosomes are not a simple stable complex, but a dynamic family of particles that assemble on the mRNA precursor and help fold it into a conformation that allows transesterification to proceed. Various spliceosome forms (e.g. A-, B- and C-complexes) have been identified. More...

Genes shared at least 5 GO terms with HNRNPA1 (count: 81)

Gene Symbol	Pathway Count	Pathway List
HNRNPA2B1	13	cytoplasm; nucleolus; spliceosomal complex; nucleoplasm; gene expression; RNA splicing; mRNA processing; mRNA splicing, via spliceosome; nucleotide binding; nucleus; RNA binding; ribonucleoprotein complex; catalytic step 2 spliceosome;
U2AF1	11	nucleolus; spliceosomal complex; nucleoplasm; gene expression; RNA splicing; mRNA processing; mRNA splicing, via spliceosome; nucleotide binding; nucleus; RNA binding; catalytic step 2 spliceosome;
EFTUD2	10	cytoplasm; nucleolus; spliceosomal complex; nucleoplasm; gene expression; RNA splicing; mRNA processing; mRNA splicing, via spliceosome; nucleus; catalytic step 2 spliceosome;
HNRNPH1	10	cytoplasm; nucleolus; nucleoplasm; gene expression; RNA splicing; mRNA splicing, via spliceosome; nucleotide binding; nucleus; RNA binding; catalytic step 2 spliceosome;
SF3A1	10	nucleolus; spliceosomal complex; nucleoplasm; gene expression; RNA splicing; mRNA processing; mRNA splicing, via spliceosome; nucleus; RNA binding; catalytic step 2 spliceosome;
SF3B2	10	nucleolus; spliceosomal complex; nucleoplasm; gene expression; RNA splicing; mRNA processing; mRNA splicing, via spliceosome; nucleus; virus-host interaction; catalytic step 2 spliceosome;
FUS	9	cytoplasm; nucleolus; nucleoplasm; gene expression; RNA splicing; mRNA splicing, via spliceosome; nucleotide binding; nucleus; RNA binding;
SF3A3	9	nucleolus; spliceosomal complex; nucleoplasm; gene expression; RNA splicing; mRNA processing; mRNA splicing, via spliceosome; nucleus; catalytic step 2 spliceosome;
DHX9	8	cytoplasm; nucleolus; nucleoplasm; gene expression; RNA splicing; mRNA splicing, via spliceosome; nucleus; ribonucleoprotein complex;
RBM4	8	cytoplasm; nucleolus; nucleoplasm; RNA splicing; mRNA processing; nucleotide binding; nucleus; RNA binding;
XPO1	8	cytoplasm; nucleolus; nucleoplasm; gene expression; RNA binding; mRNA transport; virus-host interaction; ribonucleoprotein complex;
DDX23	8	nucleolus; spliceosomal complex; nucleoplasm; gene expression; RNA splicing; mRNA splicing, via spliceosome; nucleus; catalytic step 2 spliceosome;
HSPA8	8	nucleolus; spliceosomal complex; gene expression; RNA splicing; mRNA processing; nucleus; virus-host interaction; ribonucleoprotein complex;
SNRNP200	8	nucleolus; spliceosomal complex; nucleoplasm; gene expression; RNA splicing; mRNA splicing, via spliceosome; nucleus; catalytic step 2 spliceosome;
SNW1	8	nucleolus; spliceosomal complex; nucleoplasm; gene expression; mRNA splicing, via spliceosome; nucleus; virus-host interaction; catalytic step 2 spliceosome;
HNRNPC	8	spliceosomal complex; nucleoplasm; gene expression; RNA splicing; mRNA splicing, via spliceosome; nucleotide binding; RNA binding; catalytic step 2 spliceosome;
PRPF6	8	spliceosomal complex; nucleoplasm; gene expression; RNA splicing; mRNA splicing, via spliceosome; nucleus; RNA binding; catalytic step 2 spliceosome;
PRPF8	8	spliceosomal complex; nucleoplasm; gene expression; RNA splicing; mRNA processing; mRNA splicing, via spliceosome; RNA binding; catalytic step 2 spliceosome;
SF3B4	8	spliceosomal complex; nucleoplasm; gene expression; RNA splicing; mRNA processing; mRNA splicing, via spliceosome; nucleotide binding; RNA binding;
SNRPB2	8	spliceosomal complex; nucleoplasm; gene expression; RNA splicing; mRNA processing; mRNA splicing, via spliceosome; nucleotide binding; catalytic step 2 spliceosome;
SNRPF	8	spliceosomal complex; nucleoplasm; gene expression; RNA splicing; mRNA processing; mRNA splicing, via spliceosome; RNA binding; catalytic step 2 spliceosome;
SNRPG	8	spliceosomal complex; nucleoplasm; gene expression; RNA splicing; mRNA processing; mRNA splicing, via spliceosome; RNA binding; catalytic step 2 spliceosome;
U2AF2	8	spliceosomal complex; nucleoplasm; gene expression; RNA splicing; mRNA processing; mRNA splicing, via spliceosome; nucleotide binding; RNA binding;
CPSF7	8	nucleoplasm; gene expression; RNA splicing; mRNA processing; mRNA splicing, via spliceosome; nucleotide binding; nucleus; RNA binding;
NCBP1	8	nucleoplasm; gene expression; RNA splicing; mRNA processing; mRNA splicing, via spliceosome; nucleus; RNA binding; ribonucleoprotein complex;
SMC1A	7	cytoplasm; nucleolus; nucleoplasm; gene expression; RNA splicing; mRNA splicing, via spliceosome; nucleus;
DHX8	7	nucleolus; spliceosomal complex; RNA splicing; mRNA splicing, via spliceosome; nucleus; RNA binding; catalytic step 2 spliceosome;
PRPF4	7	nucleolus; spliceosomal complex; nucleoplasm; gene expression; RNA splicing; mRNA splicing, via spliceosome; nucleus;
SCAF8	7	nucleolus; spliceosomal complex; RNA splicing; mRNA processing; nucleotide binding; nucleus; RNA binding;
SF3A2	7	spliceosomal complex; nucleoplasm; gene expression; RNA splicing; mRNA processing; mRNA splicing, via spliceosome; catalytic step 2 spliceosome;
SF3B3	7	spliceosomal complex; nucleoplasm; gene expression; RNA splicing; mRNA processing; mRNA splicing, via spliceosome; catalytic step 2 spliceosome;
SNRPA	7	spliceosomal complex; nucleoplasm; gene expression; RNA splicing; mRNA splicing, via spliceosome; nucleotide binding; RNA binding;
SNRPA1	7	spliceosomal complex; nucleoplasm; gene expression; RNA splicing; mRNA splicing, via spliceosome; RNA binding; catalytic step 2 spliceosome;
SNRPB	7	spliceosomal complex; nucleoplasm; gene expression; RNA splicing; mRNA processing; mRNA splicing, via spliceosome; catalytic step 2 spliceosome;
SNRPD3	7	spliceosomal complex; nucleoplasm; gene expression; RNA splicing; mRNA processing; mRNA splicing, via spliceosome; catalytic step 2 spliceosome;
CPSF3	7	nucleoplasm; gene expression; RNA splicing; mRNA processing; mRNA splicing, via spliceosome; RNA binding; ribonucleoprotein complex;
SNRPD1	7	nucleoplasm; gene expression; RNA splicing; mRNA splicing, via spliceosome; nucleus; RNA binding; catalytic step 2 spliceosome;
CD2BP2	6	cytoplasm; nucleoplasm; gene expression; RNA splicing; mRNA splicing, via spliceosome; nucleus;
CELF1	6	cytoplasm; mRNA processing; nucleotide binding; nucleus; RNA binding; ribonucleoprotein complex;
LARP7	6	cytoplasm; nucleoplasm; nucleotide binding; nucleus; RNA binding; ribonucleoprotein complex;
RBFOX1	6	cytoplasm; RNA splicing; mRNA processing; nucleotide binding; nucleus; RNA binding;
SART1	6	cytoplasm; nucleolus; nucleoplasm; mRNA splicing, via spliceosome; nucleus; catalytic step 2 spliceosome;
SLU7	6	cytoplasm; nucleolus; spliceosomal complex; mRNA splicing, via spliceosome; nucleus; catalytic step 2 spliceosome;
SMNDC1	6	cytoplasm; spliceosomal complex; RNA splicing; mRNA processing; nucleus; RNA binding;
ZMAT5	6	cytoplasm; nucleolus; spliceosomal complex; RNA splicing; mRNA processing; nucleus;
TARDBP	6	nucleolus; RNA splicing; mRNA processing; nucleotide binding; nucleus; RNA binding;
CDC40	6	spliceosomal complex; nucleoplasm; gene expression; RNA splicing; mRNA splicing, via spliceosome; catalytic step 2 spliceosome;
SNRPD2	6	spliceosomal complex; nucleoplasm; gene expression; RNA splicing; mRNA splicing, via spliceosome; catalytic step 2 spliceosome;
ZCRB1	6	spliceosomal complex; nucleoplasm; RNA splicing; mRNA processing; nucleotide binding; RNA binding;
POLR2G	6	nucleoplasm; gene expression; RNA splicing; mRNA splicing, via spliceosome; nucleus; RNA binding;
ATXN1	5	cytoplasm; nucleolus; nucleoplasm; nucleus; nuclear export;
ATXN2	5	cytoplasm; nucleolus; nucleus; RNA binding; ribonucleoprotein complex;
DGCR8	5	cytoplasm; nucleolus; nucleoplasm; gene expression; nucleus;
HNRNPA1L2	5	cytoplasm; spliceosomal complex; nucleotide binding; RNA binding; mRNA transport;
IGHMBP2	5	cytoplasm; nucleus; RNA binding; single-stranded DNA binding; ribonucleoprotein complex;
MAPK1	5	cytoplasm; nucleolus; nucleoplasm; nucleus; virus-host interaction;
MEN1	5	cytoplasm; nucleolus; nucleoplasm; gene expression; nucleus;
NEDD4L	5	cytoplasm; nucleoplasm; gene expression; nucleus; virus-host interaction;
NOL8	5	cytoplasm; nucleolus; nucleotide binding; nucleus; RNA binding;
PGR	5	cytoplasm; nucleolus; nucleoplasm; gene expression; nucleus;
PSMC3	5	cytoplasm; nucleoplasm; gene expression; nucleus; virus-host interaction;
PSPC1	5	cytoplasm; nucleolus; nucleotide binding; nucleus; RNA binding;
RAD23B	5	cytoplasm; nucleolus; nucleoplasm; nucleus; single-stranded DNA binding;
RAN	5	cytoplasm; nucleoplasm; gene expression; RNA export from nucleus; virus-host interaction;
RBPJ	5	cytoplasm; nucleolus; nucleoplasm; gene expression; nucleus;
SSRP1	5	cytoplasm; nucleolus; nucleoplasm; gene expression; nucleus;
TAF4B	5	cytoplasm; nucleolus; nucleoplasm; gene expression; nucleus;
DHX15	5	nucleolus; spliceosomal complex; RNA splicing; mRNA processing; nucleus;
MAPK3	5	nucleolus; nucleoplasm; gene expression; nucleus; virus-host interaction;
RBM14	5	nucleolus; nucleotide binding; nucleus; RNA binding; ribonucleoprotein complex;
RBM4B	5	nucleolus; RNA splicing; mRNA processing; nucleotide binding; RNA binding;
RBMXL2	5	nucleolus; nucleotide binding; nucleus; RNA binding; ribonucleoprotein complex;
SF1	5	nucleolus; spliceosomal complex; mRNA splicing, via spliceosome; nucleus; RNA binding;
CWC15	5	spliceosomal complex; mRNA splicing, via spliceosome; nucleus; RNA binding; catalytic step 2 spliceosome;
LSM4	5	spliceosomal complex; gene expression; RNA splicing; mRNA processing; RNA binding;
PHF5A	5	spliceosomal complex; nucleoplasm; gene expression; RNA splicing; mRNA splicing, via spliceosome;
TXNL4A	5	spliceosomal complex; nucleoplasm; gene expression; RNA splicing; mRNA splicing, via spliceosome;
CLP1	5	nucleoplasm; gene expression; RNA splicing; mRNA processing; mRNA splicing, via spliceosome;
PCF11	5	nucleoplasm; gene expression; RNA splicing; mRNA processing; mRNA splicing, via spliceosome;
SNRNP35	5	RNA splicing; mRNA processing; nucleotide binding; nucleus; RNA binding;
SRSF8	5	RNA splicing; mRNA processing; nucleotide binding; nucleus; RNA binding;

Genes shared at least 2 KEGG pathways with HNRNPA1 (count: 0)

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Region: chr12:54674488..54679030 View in gBrowse