ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	SNRPB2
Symbol Alias	Msl1
Approved Name	small nuclear ribonucleoprotein polypeptide B
Previous Name	small nuclear ribonucleoprotein polypeptide B2, "small nuclear ribonucleoprotein polypeptide B''"
Location	20p12.1
Position	chr20:16710606-16722421, +
External Links	HGNC: 11155 Entrez Gene: 6629 Ensembl: ENSG00000125870 UCSC: uc002wpi.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by PBA pathway

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 11)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 1)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005681	spliceosomal complex	Cellular Component	IDA[9731529]	51

GO terms by database search (count: 10)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0017069	snRNA binding	Molecular Function		2
GO:0010467	gene expression	Biological Process		140
GO:0071013	catalytic step 2 spliceosome	Cellular Component	IDA[11991638]	31
GO:0000398	mRNA splicing, via spliceosome	Biological Process	IC[9731529]	54
GO:0000166	nucleotide binding	Molecular Function		73
GO:0005654	nucleoplasm	Cellular Component		183
GO:0005515	protein binding	Molecular Function	IPI[9716128]	910
GO:0005686	U2 snRNP	Cellular Component	TAS[2951739]	4
GO:0008380	RNA splicing	Biological Process		65
GO:0006397	mRNA processing	Biological Process	TAS[2951739]	50

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa03040	Spliceosome	47	After transcription, eukaryotic mRNA precursors contain prot...... After transcription, eukaryotic mRNA precursors contain protein-coding exons and noncoding introns. In the following splicing, introns are excised and exons are joined by a macromolecular complex, the spliceosome. The standard spliceosome is made up of five small nuclear ribonucleoproteins (snRNPs), U1, U2, U4, U5, and U6 snRNPs, and several spliceosome-associated proteins (SAPs). Spliceosomes are not a simple stable complex, but a dynamic family of particles that assemble on the mRNA precursor and help fold it into a conformation that allows transesterification to proceed. Various spliceosome forms (e.g. A-, B- and C-complexes) have been identified. More...

Genes shared at least 5 GO terms with SNRPB2 (count: 45)

Gene Symbol	Pathway Count	Pathway List
HNRNPA2B1	9	gene expression; catalytic step 2 spliceosome; mRNA splicing, via spliceosome; nucleotide binding; nucleoplasm; protein binding; spliceosomal complex; RNA splicing; mRNA processing;
U2AF1	9	gene expression; catalytic step 2 spliceosome; mRNA splicing, via spliceosome; nucleotide binding; nucleoplasm; protein binding; spliceosomal complex; RNA splicing; mRNA processing;
SNRPA	8	snRNA binding; gene expression; mRNA splicing, via spliceosome; nucleotide binding; nucleoplasm; protein binding; spliceosomal complex; RNA splicing;
EFTUD2	8	gene expression; catalytic step 2 spliceosome; mRNA splicing, via spliceosome; nucleoplasm; protein binding; spliceosomal complex; RNA splicing; mRNA processing;
HNRNPA1	8	gene expression; catalytic step 2 spliceosome; mRNA splicing, via spliceosome; nucleotide binding; nucleoplasm; spliceosomal complex; RNA splicing; mRNA processing;
HNRNPC	8	gene expression; catalytic step 2 spliceosome; mRNA splicing, via spliceosome; nucleotide binding; nucleoplasm; protein binding; spliceosomal complex; RNA splicing;
PRPF8	8	gene expression; catalytic step 2 spliceosome; mRNA splicing, via spliceosome; nucleoplasm; protein binding; spliceosomal complex; RNA splicing; mRNA processing;
SF3A1	8	gene expression; catalytic step 2 spliceosome; mRNA splicing, via spliceosome; nucleoplasm; protein binding; spliceosomal complex; RNA splicing; mRNA processing;
SF3A3	8	gene expression; catalytic step 2 spliceosome; mRNA splicing, via spliceosome; nucleoplasm; protein binding; spliceosomal complex; RNA splicing; mRNA processing;
SF3B4	8	gene expression; mRNA splicing, via spliceosome; nucleotide binding; nucleoplasm; protein binding; spliceosomal complex; RNA splicing; mRNA processing;
SNRPA1	8	gene expression; catalytic step 2 spliceosome; mRNA splicing, via spliceosome; nucleoplasm; protein binding; U2 snRNP; spliceosomal complex; RNA splicing;
SNRPB	8	gene expression; catalytic step 2 spliceosome; mRNA splicing, via spliceosome; nucleoplasm; protein binding; spliceosomal complex; RNA splicing; mRNA processing;
SNRPD3	8	gene expression; catalytic step 2 spliceosome; mRNA splicing, via spliceosome; nucleoplasm; protein binding; spliceosomal complex; RNA splicing; mRNA processing;
SNRPG	8	gene expression; catalytic step 2 spliceosome; mRNA splicing, via spliceosome; nucleoplasm; protein binding; spliceosomal complex; RNA splicing; mRNA processing;
U2AF2	8	gene expression; mRNA splicing, via spliceosome; nucleotide binding; nucleoplasm; protein binding; spliceosomal complex; RNA splicing; mRNA processing;
CPSF7	7	gene expression; mRNA splicing, via spliceosome; nucleotide binding; nucleoplasm; protein binding; RNA splicing; mRNA processing;
DDX23	7	gene expression; catalytic step 2 spliceosome; mRNA splicing, via spliceosome; nucleoplasm; protein binding; spliceosomal complex; RNA splicing;
HNRNPH1	7	gene expression; catalytic step 2 spliceosome; mRNA splicing, via spliceosome; nucleotide binding; nucleoplasm; protein binding; RNA splicing;
PRPF6	7	gene expression; catalytic step 2 spliceosome; mRNA splicing, via spliceosome; nucleoplasm; protein binding; spliceosomal complex; RNA splicing;
SF3A2	7	gene expression; catalytic step 2 spliceosome; mRNA splicing, via spliceosome; nucleoplasm; spliceosomal complex; RNA splicing; mRNA processing;
SF3B2	7	gene expression; catalytic step 2 spliceosome; mRNA splicing, via spliceosome; nucleoplasm; spliceosomal complex; RNA splicing; mRNA processing;
SF3B3	7	gene expression; catalytic step 2 spliceosome; mRNA splicing, via spliceosome; nucleoplasm; spliceosomal complex; RNA splicing; mRNA processing;
SNRNP200	7	gene expression; catalytic step 2 spliceosome; mRNA splicing, via spliceosome; nucleoplasm; protein binding; spliceosomal complex; RNA splicing;
SNRPD2	7	gene expression; catalytic step 2 spliceosome; mRNA splicing, via spliceosome; nucleoplasm; protein binding; spliceosomal complex; RNA splicing;
SNRPF	7	gene expression; catalytic step 2 spliceosome; mRNA splicing, via spliceosome; nucleoplasm; spliceosomal complex; RNA splicing; mRNA processing;
CDC40	6	gene expression; catalytic step 2 spliceosome; mRNA splicing, via spliceosome; nucleoplasm; spliceosomal complex; RNA splicing;
CPSF3	6	gene expression; mRNA splicing, via spliceosome; nucleoplasm; protein binding; RNA splicing; mRNA processing;
FUS	6	gene expression; mRNA splicing, via spliceosome; nucleotide binding; nucleoplasm; protein binding; RNA splicing;
NCBP1	6	gene expression; mRNA splicing, via spliceosome; nucleoplasm; protein binding; RNA splicing; mRNA processing;
PHF5A	6	gene expression; mRNA splicing, via spliceosome; nucleoplasm; U2 snRNP; spliceosomal complex; RNA splicing;
PRPF4	6	gene expression; mRNA splicing, via spliceosome; nucleoplasm; protein binding; spliceosomal complex; RNA splicing;
SNRPD1	6	gene expression; catalytic step 2 spliceosome; mRNA splicing, via spliceosome; nucleoplasm; protein binding; RNA splicing;
SNW1	6	gene expression; catalytic step 2 spliceosome; mRNA splicing, via spliceosome; nucleoplasm; protein binding; spliceosomal complex;
TXNL4A	6	gene expression; mRNA splicing, via spliceosome; nucleoplasm; protein binding; spliceosomal complex; RNA splicing;
CD2BP2	5	gene expression; mRNA splicing, via spliceosome; nucleoplasm; protein binding; RNA splicing;
CLP1	5	gene expression; mRNA splicing, via spliceosome; nucleoplasm; RNA splicing; mRNA processing;
DHX9	5	gene expression; mRNA splicing, via spliceosome; nucleoplasm; protein binding; RNA splicing;
HSPA8	5	gene expression; protein binding; spliceosomal complex; RNA splicing; mRNA processing;
LSM4	5	gene expression; protein binding; spliceosomal complex; RNA splicing; mRNA processing;
PCF11	5	gene expression; mRNA splicing, via spliceosome; nucleoplasm; RNA splicing; mRNA processing;
SMC1A	5	gene expression; mRNA splicing, via spliceosome; nucleoplasm; protein binding; RNA splicing;
DHX8	5	catalytic step 2 spliceosome; mRNA splicing, via spliceosome; protein binding; spliceosomal complex; RNA splicing;
ZRSR2	5	mRNA splicing, via spliceosome; nucleotide binding; protein binding; spliceosomal complex; RNA splicing;
RBM4	5	nucleotide binding; nucleoplasm; protein binding; RNA splicing; mRNA processing;
ZCRB1	5	nucleotide binding; nucleoplasm; spliceosomal complex; RNA splicing; mRNA processing;

Genes shared at least 2 KEGG pathways with SNRPB2 (count: 0)

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Region: chr20:16710606..16722421 View in gBrowse