ADHDgene Database

Hot Results

Quick Search

Keyword:
Type:

Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	SNRPA1
Symbol Alias	Lea1
Approved Name	small nuclear ribonucleoprotein polypeptide A'
Location	15q26.3
Position	chr15:101821715-101835487, -
External Links	HGNC: 11152 Entrez Gene: 6627 Ensembl: ENSG00000131876 UCSC: uc002bww.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by PBA pathway

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 10)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 1)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005681	spliceosomal complex	Cellular Component	IDA[9731529]	51

GO terms by database search (count: 9)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0071013	catalytic step 2 spliceosome	Cellular Component	IDA[11991638]	31
GO:0030532	small nuclear ribonucleoprotein complex	Cellular Component	TAS[2928112]	12
GO:0010467	gene expression	Biological Process		140
GO:0008380	RNA splicing	Biological Process		65
GO:0005686	U2 snRNP	Cellular Component	TAS[2928112]	4
GO:0005654	nucleoplasm	Cellular Component		183
GO:0005515	protein binding	Molecular Function	IPI[9716128]	910
GO:0003723	RNA binding	Molecular Function		104
GO:0000398	mRNA splicing, via spliceosome	Biological Process	IC[9731529]	54

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa03040	Spliceosome	47	After transcription, eukaryotic mRNA precursors contain prot...... After transcription, eukaryotic mRNA precursors contain protein-coding exons and noncoding introns. In the following splicing, introns are excised and exons are joined by a macromolecular complex, the spliceosome. The standard spliceosome is made up of five small nuclear ribonucleoproteins (snRNPs), U1, U2, U4, U5, and U6 snRNPs, and several spliceosome-associated proteins (SAPs). Spliceosomes are not a simple stable complex, but a dynamic family of particles that assemble on the mRNA precursor and help fold it into a conformation that allows transesterification to proceed. Various spliceosome forms (e.g. A-, B- and C-complexes) have been identified. More...

Genes shared at least 5 GO terms with SNRPA1 (count: 42)

Gene Symbol	Pathway Count	Pathway List
SNRPG	9	catalytic step 2 spliceosome; small nuclear ribonucleoprotein complex; gene expression; RNA splicing; spliceosomal complex; nucleoplasm; protein binding; RNA binding; mRNA splicing, via spliceosome;
HNRNPA2B1	8	catalytic step 2 spliceosome; gene expression; RNA splicing; spliceosomal complex; nucleoplasm; protein binding; RNA binding; mRNA splicing, via spliceosome;
HNRNPC	8	catalytic step 2 spliceosome; gene expression; RNA splicing; spliceosomal complex; nucleoplasm; protein binding; RNA binding; mRNA splicing, via spliceosome;
PRPF6	8	catalytic step 2 spliceosome; gene expression; RNA splicing; spliceosomal complex; nucleoplasm; protein binding; RNA binding; mRNA splicing, via spliceosome;
PRPF8	8	catalytic step 2 spliceosome; gene expression; RNA splicing; spliceosomal complex; nucleoplasm; protein binding; RNA binding; mRNA splicing, via spliceosome;
SF3A1	8	catalytic step 2 spliceosome; gene expression; RNA splicing; spliceosomal complex; nucleoplasm; protein binding; RNA binding; mRNA splicing, via spliceosome;
SNRPB	8	catalytic step 2 spliceosome; small nuclear ribonucleoprotein complex; gene expression; RNA splicing; spliceosomal complex; nucleoplasm; protein binding; mRNA splicing, via spliceosome;
SNRPB2	8	catalytic step 2 spliceosome; gene expression; RNA splicing; U2 snRNP; spliceosomal complex; nucleoplasm; protein binding; mRNA splicing, via spliceosome;
SNRPD1	8	catalytic step 2 spliceosome; small nuclear ribonucleoprotein complex; gene expression; RNA splicing; nucleoplasm; protein binding; RNA binding; mRNA splicing, via spliceosome;
SNRPD2	8	catalytic step 2 spliceosome; small nuclear ribonucleoprotein complex; gene expression; RNA splicing; spliceosomal complex; nucleoplasm; protein binding; mRNA splicing, via spliceosome;
SNRPD3	8	catalytic step 2 spliceosome; small nuclear ribonucleoprotein complex; gene expression; RNA splicing; spliceosomal complex; nucleoplasm; protein binding; mRNA splicing, via spliceosome;
SNRPF	8	catalytic step 2 spliceosome; small nuclear ribonucleoprotein complex; gene expression; RNA splicing; spliceosomal complex; nucleoplasm; RNA binding; mRNA splicing, via spliceosome;
U2AF1	8	catalytic step 2 spliceosome; gene expression; RNA splicing; spliceosomal complex; nucleoplasm; protein binding; RNA binding; mRNA splicing, via spliceosome;
DDX23	7	catalytic step 2 spliceosome; gene expression; RNA splicing; spliceosomal complex; nucleoplasm; protein binding; mRNA splicing, via spliceosome;
EFTUD2	7	catalytic step 2 spliceosome; gene expression; RNA splicing; spliceosomal complex; nucleoplasm; protein binding; mRNA splicing, via spliceosome;
HNRNPA1	7	catalytic step 2 spliceosome; gene expression; RNA splicing; spliceosomal complex; nucleoplasm; RNA binding; mRNA splicing, via spliceosome;
HNRNPH1	7	catalytic step 2 spliceosome; gene expression; RNA splicing; nucleoplasm; protein binding; RNA binding; mRNA splicing, via spliceosome;
SF3A2	7	catalytic step 2 spliceosome; small nuclear ribonucleoprotein complex; gene expression; RNA splicing; spliceosomal complex; nucleoplasm; mRNA splicing, via spliceosome;
SF3A3	7	catalytic step 2 spliceosome; gene expression; RNA splicing; spliceosomal complex; nucleoplasm; protein binding; mRNA splicing, via spliceosome;
SF3B3	7	catalytic step 2 spliceosome; small nuclear ribonucleoprotein complex; gene expression; RNA splicing; spliceosomal complex; nucleoplasm; mRNA splicing, via spliceosome;
SNRNP200	7	catalytic step 2 spliceosome; gene expression; RNA splicing; spliceosomal complex; nucleoplasm; protein binding; mRNA splicing, via spliceosome;
SF3B4	7	gene expression; RNA splicing; spliceosomal complex; nucleoplasm; protein binding; RNA binding; mRNA splicing, via spliceosome;
SNRPA	7	gene expression; RNA splicing; spliceosomal complex; nucleoplasm; protein binding; RNA binding; mRNA splicing, via spliceosome;
U2AF2	7	gene expression; RNA splicing; spliceosomal complex; nucleoplasm; protein binding; RNA binding; mRNA splicing, via spliceosome;
CDC40	6	catalytic step 2 spliceosome; gene expression; RNA splicing; spliceosomal complex; nucleoplasm; mRNA splicing, via spliceosome;
DHX8	6	catalytic step 2 spliceosome; RNA splicing; spliceosomal complex; protein binding; RNA binding; mRNA splicing, via spliceosome;
SF3B2	6	catalytic step 2 spliceosome; gene expression; RNA splicing; spliceosomal complex; nucleoplasm; mRNA splicing, via spliceosome;
SNW1	6	catalytic step 2 spliceosome; gene expression; spliceosomal complex; nucleoplasm; protein binding; mRNA splicing, via spliceosome;
LSM4	6	small nuclear ribonucleoprotein complex; gene expression; RNA splicing; spliceosomal complex; protein binding; RNA binding;
SNRPN	6	small nuclear ribonucleoprotein complex; RNA splicing; U2 snRNP; spliceosomal complex; protein binding; RNA binding;
CPSF3	6	gene expression; RNA splicing; nucleoplasm; protein binding; RNA binding; mRNA splicing, via spliceosome;
CPSF7	6	gene expression; RNA splicing; nucleoplasm; protein binding; RNA binding; mRNA splicing, via spliceosome;
FUS	6	gene expression; RNA splicing; nucleoplasm; protein binding; RNA binding; mRNA splicing, via spliceosome;
NCBP1	6	gene expression; RNA splicing; nucleoplasm; protein binding; RNA binding; mRNA splicing, via spliceosome;
PHF5A	6	gene expression; RNA splicing; U2 snRNP; spliceosomal complex; nucleoplasm; mRNA splicing, via spliceosome;
PRPF4	6	gene expression; RNA splicing; spliceosomal complex; nucleoplasm; protein binding; mRNA splicing, via spliceosome;
TXNL4A	6	gene expression; RNA splicing; spliceosomal complex; nucleoplasm; protein binding; mRNA splicing, via spliceosome;
CWC15	5	catalytic step 2 spliceosome; spliceosomal complex; protein binding; RNA binding; mRNA splicing, via spliceosome;
CD2BP2	5	gene expression; RNA splicing; nucleoplasm; protein binding; mRNA splicing, via spliceosome;
DHX9	5	gene expression; RNA splicing; nucleoplasm; protein binding; mRNA splicing, via spliceosome;
POLR2G	5	gene expression; RNA splicing; nucleoplasm; RNA binding; mRNA splicing, via spliceosome;
SMC1A	5	gene expression; RNA splicing; nucleoplasm; protein binding; mRNA splicing, via spliceosome;

Genes shared at least 2 KEGG pathways with SNRPA1 (count: 0)

View in gBrowse

Region: chr15:101821715..101835487 View in gBrowse