ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	SF3B2
Symbol Alias	SAP145, SF3b1, Cus1, SF3b145
Approved Name	splicing factor 3b, subunit 2, 145kDa
Previous Name	"splicing factor 3b, subunit 2, 145kD"
Location	11q13
Position	chr11:65818200-65836779, 1
External Links	HGNC: 10769 Entrez Gene: 10992 Ensembl: ENSG00000087365 UCSC: uc001ogy.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region; Mapped by PBA pathway

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)

Gene related GO terms (count: 12)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 1)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005681	spliceosomal complex	cellular component	IDA[9731529]	43

GO terms by database search (count: 11)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005730	nucleolus	cellular component	IDA	271
GO:0005689	U12-type spliceosomal complex	cellular component	IDA[15146077]	17
GO:0000398	mRNA splicing, via spliceosome	biological process	IC[9731529]; TAS	58
GO:0006397	mRNA processing	biological process	TAS[8566756]	53
GO:0071013	catalytic step 2 spliceosome	cellular component	IDA[11991638]	33
GO:0005654	nucleoplasm	cellular component	TAS	210
GO:0003676	nucleic acid binding	molecular function	IEA	46
GO:0010467	gene expression	biological process	TAS	154
GO:0019048	virus-host interaction	biological process	IEA	61
GO:0005634	nucleus	cellular component	IDA	877
GO:0008380	RNA splicing	biological process	TAS	70

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with SF3B2 (count: 53)

Gene Symbol	Pathway Count	Pathway List
HNRNPA1	10	nucleolus; spliceosomal complex; mRNA splicing, via spliceosome; mRNA processing; catalytic step 2 spliceosome; nucleoplasm; gene expression; virus-host interaction; nucleus; RNA splicing;
SF3A3	10	nucleolus; spliceosomal complex; mRNA splicing, via spliceosome; mRNA processing; catalytic step 2 spliceosome; nucleoplasm; nucleic acid binding; gene expression; nucleus; RNA splicing;
U2AF1	9	nucleolus; spliceosomal complex; mRNA splicing, via spliceosome; mRNA processing; catalytic step 2 spliceosome; nucleoplasm; gene expression; nucleus; RNA splicing;
SF3A1	9	nucleolus; spliceosomal complex; mRNA splicing, via spliceosome; mRNA processing; catalytic step 2 spliceosome; nucleoplasm; gene expression; nucleus; RNA splicing;
EFTUD2	9	nucleolus; spliceosomal complex; mRNA splicing, via spliceosome; mRNA processing; catalytic step 2 spliceosome; nucleoplasm; gene expression; nucleus; RNA splicing;
HNRNPA2B1	9	nucleolus; spliceosomal complex; mRNA splicing, via spliceosome; mRNA processing; catalytic step 2 spliceosome; nucleoplasm; gene expression; nucleus; RNA splicing;
SNRNP200	9	nucleolus; spliceosomal complex; mRNA splicing, via spliceosome; catalytic step 2 spliceosome; nucleoplasm; nucleic acid binding; gene expression; nucleus; RNA splicing;
SF3B3	9	U12-type spliceosomal complex; spliceosomal complex; mRNA splicing, via spliceosome; mRNA processing; catalytic step 2 spliceosome; nucleoplasm; nucleic acid binding; gene expression; RNA splicing;
SNW1	8	nucleolus; spliceosomal complex; mRNA splicing, via spliceosome; catalytic step 2 spliceosome; nucleoplasm; gene expression; virus-host interaction; nucleus;
DDX23	8	nucleolus; mRNA splicing, via spliceosome; catalytic step 2 spliceosome; nucleoplasm; nucleic acid binding; gene expression; nucleus; RNA splicing;
SNRPB	8	U12-type spliceosomal complex; spliceosomal complex; mRNA splicing, via spliceosome; mRNA processing; catalytic step 2 spliceosome; nucleoplasm; gene expression; RNA splicing;
SNRPF	8	U12-type spliceosomal complex; spliceosomal complex; mRNA splicing, via spliceosome; mRNA processing; catalytic step 2 spliceosome; nucleoplasm; gene expression; RNA splicing;
SNRPD3	8	U12-type spliceosomal complex; spliceosomal complex; mRNA splicing, via spliceosome; mRNA processing; catalytic step 2 spliceosome; nucleoplasm; gene expression; RNA splicing;
SNRPG	8	U12-type spliceosomal complex; spliceosomal complex; mRNA splicing, via spliceosome; mRNA processing; catalytic step 2 spliceosome; nucleoplasm; gene expression; RNA splicing;
SF3A2	8	spliceosomal complex; mRNA splicing, via spliceosome; mRNA processing; catalytic step 2 spliceosome; nucleoplasm; nucleic acid binding; gene expression; RNA splicing;
HSPA8	7	nucleolus; spliceosomal complex; mRNA processing; gene expression; virus-host interaction; nucleus; RNA splicing;
SUGP1	7	nucleolus; spliceosomal complex; mRNA splicing, via spliceosome; nucleoplasm; gene expression; nucleus; RNA splicing;
PRPF4	7	nucleolus; spliceosomal complex; mRNA splicing, via spliceosome; nucleoplasm; gene expression; nucleus; RNA splicing;
HNRNPH1	7	nucleolus; mRNA splicing, via spliceosome; catalytic step 2 spliceosome; nucleoplasm; gene expression; nucleus; RNA splicing;
SF3B4	7	U12-type spliceosomal complex; spliceosomal complex; mRNA splicing, via spliceosome; mRNA processing; nucleoplasm; gene expression; RNA splicing;
SNRPD2	7	U12-type spliceosomal complex; spliceosomal complex; mRNA splicing, via spliceosome; catalytic step 2 spliceosome; nucleoplasm; gene expression; RNA splicing;
SNRPD1	7	U12-type spliceosomal complex; mRNA splicing, via spliceosome; catalytic step 2 spliceosome; nucleoplasm; gene expression; nucleus; RNA splicing;
SNRPB2	7	spliceosomal complex; mRNA splicing, via spliceosome; mRNA processing; catalytic step 2 spliceosome; nucleoplasm; gene expression; RNA splicing;
PRPF6	7	spliceosomal complex; mRNA splicing, via spliceosome; catalytic step 2 spliceosome; nucleoplasm; gene expression; nucleus; RNA splicing;
DHX8	6	nucleolus; spliceosomal complex; mRNA splicing, via spliceosome; catalytic step 2 spliceosome; nucleus; RNA splicing;
FUS	6	nucleolus; mRNA splicing, via spliceosome; nucleoplasm; gene expression; nucleus; RNA splicing;
DHX15	6	nucleolus; U12-type spliceosomal complex; mRNA processing; nucleic acid binding; nucleus; RNA splicing;
DHX9	6	nucleolus; mRNA splicing, via spliceosome; nucleoplasm; gene expression; nucleus; RNA splicing;
SMC1A	6	nucleolus; mRNA splicing, via spliceosome; nucleoplasm; gene expression; nucleus; RNA splicing;
ZMAT5	6	nucleolus; U12-type spliceosomal complex; mRNA processing; nucleic acid binding; nucleus; RNA splicing;
GEMIN2	6	spliceosomal complex; mRNA processing; nucleoplasm; gene expression; nucleus; RNA splicing;
CDC40	6	spliceosomal complex; mRNA splicing, via spliceosome; catalytic step 2 spliceosome; nucleoplasm; gene expression; RNA splicing;
HNRNPC	6	spliceosomal complex; mRNA splicing, via spliceosome; catalytic step 2 spliceosome; nucleoplasm; gene expression; RNA splicing;
U2AF2	6	spliceosomal complex; mRNA splicing, via spliceosome; mRNA processing; nucleoplasm; gene expression; RNA splicing;
SNRPA1	6	spliceosomal complex; mRNA splicing, via spliceosome; catalytic step 2 spliceosome; nucleoplasm; gene expression; RNA splicing;
NCBP1	6	mRNA splicing, via spliceosome; mRNA processing; nucleoplasm; gene expression; nucleus; RNA splicing;
CPSF7	6	mRNA splicing, via spliceosome; mRNA processing; nucleoplasm; gene expression; nucleus; RNA splicing;
PRPF8	6	mRNA splicing, via spliceosome; mRNA processing; catalytic step 2 spliceosome; nucleoplasm; gene expression; RNA splicing;
MAPK3	5	nucleolus; nucleoplasm; gene expression; virus-host interaction; nucleus;
SF1	5	nucleolus; spliceosomal complex; mRNA splicing, via spliceosome; nucleic acid binding; nucleus;
SLU7	5	nucleolus; spliceosomal complex; mRNA splicing, via spliceosome; catalytic step 2 spliceosome; nucleus;
SCAF8	5	nucleolus; spliceosomal complex; mRNA processing; nucleus; RNA splicing;
RBM4	5	nucleolus; mRNA processing; nucleoplasm; nucleus; RNA splicing;
SART1	5	nucleolus; mRNA splicing, via spliceosome; catalytic step 2 spliceosome; nucleoplasm; nucleus;
PHF5A	5	U12-type spliceosomal complex; mRNA splicing, via spliceosome; nucleoplasm; gene expression; RNA splicing;
TXNL4A	5	spliceosomal complex; mRNA splicing, via spliceosome; nucleoplasm; gene expression; RNA splicing;
SNRPA	5	spliceosomal complex; mRNA splicing, via spliceosome; nucleoplasm; gene expression; RNA splicing;
CLP1	5	mRNA splicing, via spliceosome; mRNA processing; nucleoplasm; gene expression; RNA splicing;
RNPS1	5	mRNA splicing, via spliceosome; nucleoplasm; gene expression; nucleus; RNA splicing;
PCF11	5	mRNA splicing, via spliceosome; mRNA processing; nucleoplasm; gene expression; RNA splicing;
POLR2G	5	mRNA splicing, via spliceosome; nucleoplasm; gene expression; nucleus; RNA splicing;
CD2BP2	5	mRNA splicing, via spliceosome; nucleoplasm; gene expression; nucleus; RNA splicing;
CPSF3	5	mRNA splicing, via spliceosome; mRNA processing; nucleoplasm; gene expression; RNA splicing;

Genes shared at least 2 KEGG pathways with SF3B2 (count: 0)

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Region: chr11:65818200..65836779 View in gBrowse