ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	SMC1A
Previous Symbol	SMC1L1
Symbol Alias	DXS423E, KIAA0178, SB1.8, Smcb
Approved Name	structural maintenance of chromosomes 1A
Previous Name	SMC1 (structural maintenance of chromosomes 1, yeast)-like 1, "SMC1 structural maintenance of chromosomes 1-like 1 (yeast)"
Location	Xp11.22-p11.21
Position	chrX:53401070-53449677, -
External Links	HGNC: 11111 Entrez Gene: 8243 Ensembl: ENSG00000072501 UCSC: uc004dsg.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by PBA pathway

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 37)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 1)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0000226	microtubule cytoskeleton organization	Biological Process		39

GO terms by database search (count: 36)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005730	nucleolus	Cellular Component		243
GO:0005654	nucleoplasm	Cellular Component		183
GO:0006281	DNA repair	Biological Process	TAS[11877377]	62
GO:0005737	cytoplasm	Cellular Component		690
GO:0007052	mitotic spindle organization	Biological Process	TAS[12199140]	7
GO:0006310	DNA recombination	Biological Process		14
GO:0007064	mitotic sister chromatid cohesion	Biological Process	TAS[12199140]	3
GO:0007062	sister chromatid cohesion	Biological Process	IMP[15917200]	5
GO:0000777	condensed chromosome kinetochore	Cellular Component		13
GO:0000776	kinetochore	Cellular Component	IDA[11682612]	15
GO:0003682	chromatin binding	Molecular Function	IDA[11076961]	48
GO:0000794	condensed nuclear chromosome	Cellular Component	TAS[7757074]	6
GO:0005515	protein binding	Molecular Function	IPI[16438930]	910
GO:0003777	microtubule motor activity	Molecular Function	NAS[12199140]	17
GO:0005634	nucleus	Cellular Component		770
GO:0005524	ATP binding	Molecular Function		228
GO:0000070	mitotic sister chromatid segregation	Biological Process	TAS[7757074]	4
GO:0000075	cell cycle checkpoint	Biological Process	IDA[11877377]	21
GO:0000087	M phase of mitotic cell cycle	Biological Process		19
GO:0000236	mitotic prometaphase	Biological Process		17
GO:0000278	mitotic cell cycle	Biological Process		63
GO:0000398	mRNA splicing, via spliceosome	Biological Process		54
GO:0036033	mediator complex binding	Molecular Function		4
GO:0042770	signal transduction in response to DNA damage	Biological Process	IDA[11877377]	1
GO:0030893	meiotic cohesin complex	Cellular Component		3
GO:0032876	negative regulation of DNA endoreduplication	Biological Process	IMP[15917200]	3
GO:0046982	protein heterodimerization activity	Molecular Function	IPI[11590136]	68
GO:0051301	cell division	Biological Process		58
GO:0008280	cohesin core heterodimer	Cellular Component	TAS[11076961]	1
GO:0008380	RNA splicing	Biological Process		65
GO:0007091	mitotic metaphase/anaphase transition	Biological Process		4
GO:0007126	meiosis	Biological Process		11
GO:0019827	stem cell maintenance	Biological Process		12
GO:0030261	chromosome condensation	Biological Process		2
GO:0009314	response to radiation	Biological Process	IEP[11877377]	5
GO:0010467	gene expression	Biological Process		140

Gene related KEGG pathways (count: 2)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa04110	Cell cycle	19	Mitotic cell cycle progression is accomplished through a rep...... Mitotic cell cycle progression is accomplished through a reproducible sequence of events, DNA replication (S phase) and mitosis (M phase) separated temporally by gaps known as G1 and G2 phases. Cyclin-dependent kinases (CDKs) are key regulatory enzymes, each consisting of a catalytic CDK subunit and an activating cyclin subunit. CDKs regulate the cell's progression through the phases of the cell cycle by modulating the activity of key substrates. Downstream targets of CDKs include transcription factor E2F and its regulator Rb. Precise activation and inactivation of CDKs at specific points in the cell cycle are required for orderly cell division. Cyclin-CDK inhibitors (CKIs), such as p16Ink4a, p15Ink4b, p27Kip1, and p21Cip1, are involved in the negative regulation of CDK activities, thus providing a pathway through which the cell cycle is negatively regulated. More...
hsa04114	Oocyte meiosis	22	During meiosis, a single round of DNA replication is followe...... During meiosis, a single round of DNA replication is followed by two rounds of chromosome segregation, called meiosis I and meiosis II. At meiosis I, homologous chromosomes recombine and then segregate to opposite poles, while the sister chromatids segregate from each other at meoisis II. In vertebrates, immature oocytes are arrested at the PI (prophase of meiosis I). The resumption of meiosis is stimulated by progesterone, which carries the oocyte through two consecutive M-phases (MI and MII) to a second arrest at MII. The key activity driving meiotic progression is the MPF (maturation-promoting factor), a heterodimer of CDC2 (cell division cycle 2 kinase) and cyclin B. In PI-arrested oocytes, MPF is initially inactive and is activated by the dual-specificity CDC25C phosphatase as the result of new synthesis of Mos induced by progesterone. MPF activation mediates the transition from the PI arrest to MI. The subsequent decrease in MPF levels, required to exit from MI into interkinesis, is induced by a negative feedback loop, where CDC2 brings about the activation of the APC (anaphase-promoting complex), which mediates destruction of cyclin B. Re-activation of MPF for MII requires re-accumulation of high levels of cyclin B as well as the inactivation of the APC by newly synthesized Emi2 and other components of the CSF (cytostatic factor), such as cyclin E or high levels of Mos. CSF antagonizes the ubiquitin ligase activity of the APC, preventing cyclin B destruction and meiotic exit until fertilization occurs. Fertilization triggers a transient increase in cytosolic free Ca2+, which leads to CSF inactivation and cyclin B destruction through the APC. Then eggs are released from MII into the first embryonic cell cycle. More...

Genes shared at least 5 GO terms with SMC1A (count: 156)

Gene Symbol	Pathway Count	Pathway List
SMC3	22	nucleoplasm; DNA repair; cytoplasm; mitotic spindle organization; sister chromatid cohesion; chromatin binding; protein binding; microtubule motor activity; nucleus; ATP binding; M phase of mitotic cell cycle; microtubule cytoskeleton organization; mitotic prometaphase; mitotic cell cycle; mediator complex binding; meiotic cohesin complex; negative regulation of DNA endoreduplication; protein heterodimerization activity; cell division; mitotic metaphase/anaphase transition; meiosis; stem cell maintenance;
KIF2C	11	condensed chromosome kinetochore; kinetochore; protein binding; microtubule motor activity; nucleus; ATP binding; M phase of mitotic cell cycle; microtubule cytoskeleton organization; mitotic prometaphase; mitotic cell cycle; cell division;
RCC1	10	nucleolus; nucleoplasm; cytoplasm; mitotic spindle organization; chromatin binding; condensed nuclear chromosome; protein binding; nucleus; microtubule cytoskeleton organization; cell division;
ZW10	10	condensed chromosome kinetochore; kinetochore; protein binding; nucleus; mitotic sister chromatid segregation; M phase of mitotic cell cycle; mitotic prometaphase; mitotic cell cycle; cell division; meiosis;
DHX9	9	nucleolus; nucleoplasm; cytoplasm; protein binding; nucleus; ATP binding; mRNA splicing, via spliceosome; RNA splicing; gene expression;
MRE11A	9	nucleolus; nucleoplasm; DNA repair; DNA recombination; sister chromatid cohesion; protein binding; nucleus; cell cycle checkpoint; negative regulation of DNA endoreduplication;
PAFAH1B1	9	nucleolus; cytoplasm; kinetochore; protein binding; nucleus; M phase of mitotic cell cycle; microtubule cytoskeleton organization; mitotic prometaphase; mitotic cell cycle;
XPO1	9	nucleolus; nucleoplasm; cytoplasm; kinetochore; protein binding; M phase of mitotic cell cycle; mitotic prometaphase; mitotic cell cycle; gene expression;
PLK1	9	nucleoplasm; kinetochore; protein binding; nucleus; ATP binding; M phase of mitotic cell cycle; mitotic prometaphase; mitotic cell cycle; mitotic metaphase/anaphase transition;
SMC2	9	DNA repair; cytoplasm; DNA recombination; sister chromatid cohesion; protein binding; nucleus; ATP binding; protein heterodimerization activity; cell division;
DDX23	8	nucleolus; nucleoplasm; protein binding; nucleus; ATP binding; mRNA splicing, via spliceosome; RNA splicing; gene expression;
EFTUD2	8	nucleolus; nucleoplasm; cytoplasm; protein binding; nucleus; mRNA splicing, via spliceosome; RNA splicing; gene expression;
FUS	8	nucleolus; nucleoplasm; cytoplasm; protein binding; nucleus; mRNA splicing, via spliceosome; RNA splicing; gene expression;
HNRNPA2B1	8	nucleolus; nucleoplasm; cytoplasm; protein binding; nucleus; mRNA splicing, via spliceosome; RNA splicing; gene expression;
HNRNPH1	8	nucleolus; nucleoplasm; cytoplasm; protein binding; nucleus; mRNA splicing, via spliceosome; RNA splicing; gene expression;
MEN1	8	nucleolus; nucleoplasm; DNA repair; cytoplasm; chromatin binding; protein binding; nucleus; gene expression;
SNRNP200	8	nucleolus; nucleoplasm; protein binding; nucleus; ATP binding; mRNA splicing, via spliceosome; RNA splicing; gene expression;
SSRP1	8	nucleolus; nucleoplasm; DNA repair; cytoplasm; chromatin binding; protein binding; nucleus; gene expression;
XRCC5	8	nucleolus; nucleoplasm; DNA repair; cytoplasm; DNA recombination; protein binding; nucleus; ATP binding;
KIF23	8	nucleoplasm; protein binding; microtubule motor activity; nucleus; ATP binding; M phase of mitotic cell cycle; microtubule cytoskeleton organization; mitotic cell cycle;
PSMC3	8	nucleoplasm; cytoplasm; protein binding; nucleus; ATP binding; cell cycle checkpoint; mitotic cell cycle; gene expression;
RAN	8	nucleoplasm; cytoplasm; mitotic spindle organization; chromatin binding; protein binding; microtubule cytoskeleton organization; cell division; gene expression;
CENPC1	8	cytoplasm; condensed chromosome kinetochore; kinetochore; nucleus; M phase of mitotic cell cycle; mitotic prometaphase; mitotic cell cycle; cell division;
CLASP2	8	cytoplasm; condensed chromosome kinetochore; protein binding; M phase of mitotic cell cycle; microtubule cytoskeleton organization; mitotic prometaphase; mitotic cell cycle; cell division;
CLASP1	8	condensed chromosome kinetochore; kinetochore; protein binding; M phase of mitotic cell cycle; microtubule cytoskeleton organization; mitotic prometaphase; mitotic cell cycle; cell division;
CDCA5	7	nucleolus; cytoplasm; mitotic sister chromatid cohesion; chromatin binding; protein binding; nucleus; cell division;
CENPW	7	nucleolus; condensed chromosome kinetochore; kinetochore; protein binding; mitotic cell cycle; protein heterodimerization activity; cell division;
CEP164	7	nucleolus; DNA repair; cytoplasm; protein binding; nucleus; mitotic cell cycle; cell division;
HNRNPA1	7	nucleolus; nucleoplasm; cytoplasm; nucleus; mRNA splicing, via spliceosome; RNA splicing; gene expression;
MED1	7	nucleolus; nucleoplasm; chromatin binding; protein binding; nucleus; mediator complex binding; gene expression;
NCOA6	7	nucleolus; nucleoplasm; DNA repair; DNA recombination; chromatin binding; protein binding; nucleus;
NUMA1	7	nucleolus; nucleoplasm; cytoplasm; protein binding; nucleus; mitotic cell cycle; cell division;
PRPF4	7	nucleolus; nucleoplasm; protein binding; nucleus; mRNA splicing, via spliceosome; RNA splicing; gene expression;
RAD9A	7	nucleolus; nucleoplasm; DNA repair; cytoplasm; protein binding; nucleus; cell cycle checkpoint;
RBPJ	7	nucleolus; nucleoplasm; cytoplasm; DNA recombination; protein binding; nucleus; gene expression;
SF3A1	7	nucleolus; nucleoplasm; protein binding; nucleus; mRNA splicing, via spliceosome; RNA splicing; gene expression;
SF3A3	7	nucleolus; nucleoplasm; protein binding; nucleus; mRNA splicing, via spliceosome; RNA splicing; gene expression;
U2AF1	7	nucleolus; nucleoplasm; protein binding; nucleus; mRNA splicing, via spliceosome; RNA splicing; gene expression;
CD2BP2	7	nucleoplasm; cytoplasm; protein binding; nucleus; mRNA splicing, via spliceosome; RNA splicing; gene expression;
CHEK1	7	nucleoplasm; DNA repair; condensed nuclear chromosome; protein binding; nucleus; ATP binding; cell cycle checkpoint;
H2AFX	7	nucleoplasm; DNA repair; condensed nuclear chromosome; protein binding; nucleus; protein heterodimerization activity; meiosis;
MAPRE1	7	cytoplasm; protein binding; M phase of mitotic cell cycle; microtubule cytoskeleton organization; mitotic prometaphase; mitotic cell cycle; cell division;
NDE1	7	condensed chromosome kinetochore; kinetochore; protein binding; M phase of mitotic cell cycle; mitotic prometaphase; mitotic cell cycle; cell division;
CENPV	6	nucleolus; cytoplasm; condensed chromosome kinetochore; kinetochore; nucleus; cell division;
CHD1L	6	nucleolus; DNA repair; cytoplasm; protein binding; nucleus; ATP binding;
DGCR8	6	nucleolus; nucleoplasm; cytoplasm; protein binding; nucleus; gene expression;
DHX8	6	nucleolus; protein binding; nucleus; ATP binding; mRNA splicing, via spliceosome; RNA splicing;
FEN1	6	nucleolus; nucleoplasm; DNA repair; protein binding; nucleus; mitotic cell cycle;
HINFP	6	nucleolus; nucleoplasm; DNA repair; chromatin binding; protein binding; nucleus;
HSPA8	6	nucleolus; protein binding; nucleus; ATP binding; RNA splicing; gene expression;
IARS	6	nucleolus; cytoplasm; protein binding; nucleus; ATP binding; gene expression;
MAPK1	6	nucleolus; nucleoplasm; cytoplasm; protein binding; nucleus; ATP binding;
MAPK3	6	nucleolus; nucleoplasm; protein binding; nucleus; ATP binding; gene expression;
NCOR2	6	nucleolus; nucleoplasm; chromatin binding; protein binding; nucleus; gene expression;
PGR	6	nucleolus; nucleoplasm; cytoplasm; protein binding; nucleus; gene expression;
POLA2	6	nucleolus; nucleoplasm; cytoplasm; nucleus; mitotic cell cycle; protein heterodimerization activity;
POLD3	6	nucleolus; nucleoplasm; DNA repair; protein binding; nucleus; mitotic cell cycle;
RAD1	6	nucleolus; nucleoplasm; DNA repair; protein binding; nucleus; cell cycle checkpoint;
RAD23B	6	nucleolus; nucleoplasm; DNA repair; cytoplasm; protein binding; nucleus;
RBM4	6	nucleolus; nucleoplasm; cytoplasm; protein binding; nucleus; RNA splicing;
RFWD2	6	nucleolus; nucleoplasm; cytoplasm; protein binding; nucleus; cell cycle checkpoint;
SART1	6	nucleolus; nucleoplasm; cytoplasm; protein binding; nucleus; mRNA splicing, via spliceosome;
SF3B2	6	nucleolus; nucleoplasm; nucleus; mRNA splicing, via spliceosome; RNA splicing; gene expression;
SNW1	6	nucleolus; nucleoplasm; protein binding; nucleus; mRNA splicing, via spliceosome; gene expression;
TAF13	6	nucleolus; nucleoplasm; protein binding; nucleus; protein heterodimerization activity; gene expression;
TAF4B	6	nucleolus; nucleoplasm; cytoplasm; nucleus; protein heterodimerization activity; gene expression;
CDC45	6	nucleoplasm; cytoplasm; protein binding; nucleus; cell cycle checkpoint; mitotic cell cycle;
CPSF7	6	nucleoplasm; protein binding; nucleus; mRNA splicing, via spliceosome; RNA splicing; gene expression;
DDB1	6	nucleoplasm; DNA repair; cytoplasm; protein binding; nucleus; cell cycle checkpoint;
NCBP1	6	nucleoplasm; protein binding; nucleus; mRNA splicing, via spliceosome; RNA splicing; gene expression;
NCOR1	6	nucleoplasm; cytoplasm; chromatin binding; protein binding; nucleus; gene expression;
NR4A2	6	nucleoplasm; cytoplasm; protein binding; nucleus; protein heterodimerization activity; gene expression;
POLR2G	6	nucleoplasm; DNA repair; nucleus; mRNA splicing, via spliceosome; RNA splicing; gene expression;
PRPF6	6	nucleoplasm; protein binding; nucleus; mRNA splicing, via spliceosome; RNA splicing; gene expression;
SNRPD1	6	nucleoplasm; protein binding; nucleus; mRNA splicing, via spliceosome; RNA splicing; gene expression;
TP53BP1	6	nucleoplasm; DNA repair; cytoplasm; condensed chromosome kinetochore; protein binding; nucleus;
TXNL4A	6	nucleoplasm; protein binding; mRNA splicing, via spliceosome; cell division; RNA splicing; gene expression;
UBB	6	nucleoplasm; DNA repair; protein binding; cell cycle checkpoint; mitotic cell cycle; gene expression;
UBC	6	nucleoplasm; DNA repair; protein binding; cell cycle checkpoint; mitotic cell cycle; gene expression;
YAP1	6	nucleoplasm; cytoplasm; chromatin binding; protein binding; nucleus; gene expression;
IGHMBP2	6	DNA repair; cytoplasm; DNA recombination; protein binding; nucleus; ATP binding;
KIF22	6	DNA repair; cytoplasm; kinetochore; microtubule motor activity; nucleus; ATP binding;
PTTG1	6	DNA repair; cytoplasm; protein binding; nucleus; mitotic cell cycle; cell division;
RBBP8	6	DNA repair; protein binding; nucleus; cell cycle checkpoint; cell division; meiosis;
SMG1	6	DNA repair; cytoplasm; protein binding; nucleus; ATP binding; gene expression;
APC	6	cytoplasm; kinetochore; protein binding; nucleus; microtubule cytoskeleton organization; mitotic metaphase/anaphase transition;
KIF11	6	cytoplasm; mitotic spindle organization; microtubule motor activity; ATP binding; microtubule cytoskeleton organization; cell division;
NIPBL	6	mitotic sister chromatid cohesion; chromatin binding; protein binding; nucleus; mediator complex binding; stem cell maintenance;
INCENP	6	condensed chromosome kinetochore; kinetochore; protein binding; M phase of mitotic cell cycle; mitotic prometaphase; mitotic cell cycle;
CKAP5	6	protein binding; M phase of mitotic cell cycle; microtubule cytoskeleton organization; mitotic prometaphase; mitotic cell cycle; cell division;
ATXN1	5	nucleolus; nucleoplasm; cytoplasm; protein binding; nucleus;
CDK12	5	nucleolus; protein binding; nucleus; ATP binding; RNA splicing;
CEP57	5	nucleolus; cytoplasm; protein binding; nucleus; mitotic cell cycle;
DCPS	5	nucleolus; cytoplasm; protein binding; nucleus; gene expression;
FOXP1	5	nucleolus; cytoplasm; chromatin binding; nucleus; protein heterodimerization activity;
GSK3B	5	nucleolus; cytoplasm; protein binding; nucleus; ATP binding;
INO80E	5	nucleolus; DNA repair; DNA recombination; protein binding; nucleus;
MAML1	5	nucleolus; nucleoplasm; protein binding; nucleus; gene expression;
MED4	5	nucleolus; nucleoplasm; protein binding; nucleus; gene expression;
MPHOSPH6	5	nucleolus; cytoplasm; protein binding; nucleus; M phase of mitotic cell cycle;
NFRKB	5	nucleolus; DNA repair; DNA recombination; protein binding; nucleus;
NUSAP1	5	nucleolus; cytoplasm; nucleus; mitotic sister chromatid segregation; microtubule cytoskeleton organization;
PPP1CA	5	nucleolus; cytoplasm; protein binding; nucleus; cell division;
PRC1	5	nucleolus; cytoplasm; protein binding; nucleus; microtubule cytoskeleton organization;
RBM14	5	nucleolus; DNA repair; DNA recombination; protein binding; nucleus;
RNF2	5	nucleolus; chromatin binding; protein binding; nucleus; mitotic cell cycle;
RPS6KA4	5	nucleolus; cytoplasm; protein binding; nucleus; ATP binding;
TFAP2A	5	nucleolus; cytoplasm; chromatin binding; protein binding; nucleus;
THRAP3	5	nucleolus; protein binding; nucleus; ATP binding; RNA splicing;
TUBGCP2	5	nucleolus; protein binding; nucleus; microtubule cytoskeleton organization; mitotic cell cycle;
USP28	5	nucleolus; nucleoplasm; DNA repair; protein binding; nucleus;
ANAPC4	5	nucleoplasm; nucleus; cell cycle checkpoint; mitotic cell cycle; cell division;
ATM	5	nucleoplasm; DNA repair; protein binding; ATP binding; cell cycle checkpoint;
BNIP3	5	nucleoplasm; cytoplasm; protein binding; nucleus; protein heterodimerization activity;
CCND1	5	nucleoplasm; protein binding; nucleus; mitotic cell cycle; cell division;
CDC26	5	nucleoplasm; protein binding; cell cycle checkpoint; mitotic cell cycle; cell division;
CENPN	5	nucleoplasm; condensed chromosome kinetochore; M phase of mitotic cell cycle; mitotic prometaphase; mitotic cell cycle;
CLP1	5	nucleoplasm; ATP binding; mRNA splicing, via spliceosome; RNA splicing; gene expression;
CPSF3	5	nucleoplasm; protein binding; mRNA splicing, via spliceosome; RNA splicing; gene expression;
E2F5	5	nucleoplasm; cytoplasm; protein binding; mitotic cell cycle; gene expression;
FANCA	5	nucleoplasm; DNA repair; cytoplasm; protein binding; nucleus;
FANCC	5	nucleoplasm; DNA repair; cytoplasm; protein binding; nucleus;
HNRNPC	5	nucleoplasm; protein binding; mRNA splicing, via spliceosome; RNA splicing; gene expression;
MED12	5	nucleoplasm; chromatin binding; nucleus; stem cell maintenance; gene expression;
MED15	5	nucleoplasm; protein binding; nucleus; stem cell maintenance; gene expression;
MED30	5	nucleoplasm; protein binding; nucleus; stem cell maintenance; gene expression;
NEDD4L	5	nucleoplasm; cytoplasm; protein binding; nucleus; gene expression;
NR5A1	5	nucleoplasm; chromatin binding; protein binding; nucleus; gene expression;
POLD4	5	nucleoplasm; DNA repair; protein binding; nucleus; mitotic cell cycle;
POLE	5	nucleoplasm; DNA repair; chromatin binding; nucleus; mitotic cell cycle;
PRPF8	5	nucleoplasm; protein binding; mRNA splicing, via spliceosome; RNA splicing; gene expression;
PSMB7	5	nucleoplasm; protein binding; cell cycle checkpoint; mitotic cell cycle; gene expression;
PSMD5	5	nucleoplasm; protein binding; cell cycle checkpoint; mitotic cell cycle; gene expression;
PSMD7	5	nucleoplasm; protein binding; cell cycle checkpoint; mitotic cell cycle; gene expression;
PSME1	5	nucleoplasm; cytoplasm; cell cycle checkpoint; mitotic cell cycle; gene expression;
RELA	5	nucleoplasm; cytoplasm; chromatin binding; protein binding; nucleus;
SF3B4	5	nucleoplasm; protein binding; mRNA splicing, via spliceosome; RNA splicing; gene expression;
SNRPA	5	nucleoplasm; protein binding; mRNA splicing, via spliceosome; RNA splicing; gene expression;
SNRPA1	5	nucleoplasm; protein binding; mRNA splicing, via spliceosome; RNA splicing; gene expression;
SNRPB	5	nucleoplasm; protein binding; mRNA splicing, via spliceosome; RNA splicing; gene expression;
SNRPB2	5	nucleoplasm; protein binding; mRNA splicing, via spliceosome; RNA splicing; gene expression;
SNRPD2	5	nucleoplasm; protein binding; mRNA splicing, via spliceosome; RNA splicing; gene expression;
SNRPD3	5	nucleoplasm; protein binding; mRNA splicing, via spliceosome; RNA splicing; gene expression;
SNRPG	5	nucleoplasm; protein binding; mRNA splicing, via spliceosome; RNA splicing; gene expression;
TAF10	5	nucleoplasm; cytoplasm; protein binding; nucleus; gene expression;
TRIP12	5	nucleoplasm; DNA repair; cytoplasm; protein binding; nucleus;
U2AF2	5	nucleoplasm; protein binding; mRNA splicing, via spliceosome; RNA splicing; gene expression;
BARD1	5	DNA repair; cytoplasm; protein binding; nucleus; protein heterodimerization activity;
CSNK1E	5	DNA repair; protein binding; nucleus; ATP binding; mitotic cell cycle;
NDNL2	5	DNA repair; cytoplasm; DNA recombination; protein binding; nucleus;
PRPF19	5	DNA repair; cytoplasm; protein binding; nucleus; mRNA splicing, via spliceosome;
CDK20	5	cytoplasm; protein binding; nucleus; ATP binding; cell division;
PRKCB	5	cytoplasm; chromatin binding; protein binding; nucleus; ATP binding;
TUBG1	5	cytoplasm; condensed nuclear chromosome; protein binding; microtubule cytoskeleton organization; mitotic cell cycle;
UXT	5	cytoplasm; chromatin binding; protein binding; nucleus; microtubule cytoskeleton organization;
KIFC1	5	microtubule motor activity; nucleus; ATP binding; mitotic sister chromatid segregation; cell division;

Genes shared at least 2 KEGG pathways with SMC1A (count: 7)

Gene Symbol	Pathway Count	Pathway List
ANAPC4	2	Cell cycle; Oocyte meiosis;
CDC26	2	Cell cycle; Oocyte meiosis;
PLK1	2	Cell cycle; Oocyte meiosis;
PTTG1	2	Cell cycle; Oocyte meiosis;
SMC3	2	Cell cycle; Oocyte meiosis;
YWHAH	2	Cell cycle; Oocyte meiosis;
YWHAQ	2	Cell cycle; Oocyte meiosis;

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Region: chrX:53401070..53449677 View in gBrowse