ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	CKAP5
Symbol Alias	ch-TOG, KIAA0097, TOG, TOGp
Approved Name	cytoskeleton associated protein 5
Location	11p11.2
Position	chr11:46764598-46867847, -
External Links	HGNC: 28959 Entrez Gene: 9793 Ensembl: ENSG00000175216 UCSC: uc001ndi.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by PBA pathway

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 18)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 1)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0000226	microtubule cytoskeleton organization	Biological Process		39

GO terms by database search (count: 17)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0007051	spindle organization	Biological Process	IMP[14718566]	5
GO:0015630	microtubule cytoskeleton	Cellular Component	ISS[15703215]	34
GO:0005813	centrosome	Cellular Component	IDA[14718566]	71
GO:0005829	cytosol	Cellular Component		447
GO:0000930	gamma-tubulin complex	Cellular Component	IDA[14718566]	3
GO:0005515	protein binding	Molecular Function	IPI[17474147]	910
GO:0000278	mitotic cell cycle	Biological Process		63
GO:0000922	spindle pole	Cellular Component		22
GO:0051297	centrosome organization	Biological Process	IMP[14718566]	5
GO:0051301	cell division	Biological Process		58
GO:0043234	protein complex	Cellular Component	IDA[18468998]	45
GO:0050658	RNA transport	Biological Process	ISS[15703215]	4
GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity	Biological Process	IMP[14718566]	2
GO:0035371	microtubule plus end	Cellular Component		3
GO:0000236	mitotic prometaphase	Biological Process		17
GO:0000087	M phase of mitotic cell cycle	Biological Process		19
GO:0000086	G2/M transition of mitotic cell cycle	Biological Process		29

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with CKAP5 (count: 35)

Gene Symbol	Pathway Count	Pathway List
MAPRE1	10	centrosome; cytosol; protein binding; mitotic cell cycle; cell division; microtubule plus end; mitotic prometaphase; microtubule cytoskeleton organization; M phase of mitotic cell cycle; G2/M transition of mitotic cell cycle;
KIF2C	9	microtubule cytoskeleton; cytosol; protein binding; mitotic cell cycle; cell division; establishment or maintenance of microtubule cytoskeleton polarity; mitotic prometaphase; microtubule cytoskeleton organization; M phase of mitotic cell cycle;
CLASP1	9	centrosome; cytosol; protein binding; mitotic cell cycle; cell division; mitotic prometaphase; microtubule cytoskeleton organization; M phase of mitotic cell cycle; G2/M transition of mitotic cell cycle;
PLK1	9	centrosome; cytosol; protein binding; mitotic cell cycle; spindle pole; centrosome organization; mitotic prometaphase; M phase of mitotic cell cycle; G2/M transition of mitotic cell cycle;
CDK5RAP2	8	centrosome; cytosol; protein binding; mitotic cell cycle; spindle pole; centrosome organization; microtubule cytoskeleton organization; G2/M transition of mitotic cell cycle;
NDE1	8	centrosome; cytosol; protein binding; mitotic cell cycle; cell division; mitotic prometaphase; M phase of mitotic cell cycle; G2/M transition of mitotic cell cycle;
PAFAH1B1	8	centrosome; cytosol; protein binding; mitotic cell cycle; mitotic prometaphase; microtubule cytoskeleton organization; M phase of mitotic cell cycle; G2/M transition of mitotic cell cycle;
CENPJ	7	centrosome; cytosol; protein binding; mitotic cell cycle; cell division; microtubule cytoskeleton organization; G2/M transition of mitotic cell cycle;
TUBG1	7	centrosome; cytosol; gamma-tubulin complex; protein binding; mitotic cell cycle; microtubule cytoskeleton organization; G2/M transition of mitotic cell cycle;
TUBGCP2	7	centrosome; cytosol; protein binding; mitotic cell cycle; spindle pole; microtubule cytoskeleton organization; G2/M transition of mitotic cell cycle;
CLASP2	7	cytosol; protein binding; mitotic cell cycle; cell division; mitotic prometaphase; microtubule cytoskeleton organization; M phase of mitotic cell cycle;
ZW10	7	cytosol; protein binding; mitotic cell cycle; spindle pole; cell division; mitotic prometaphase; M phase of mitotic cell cycle;
SMC3	7	protein binding; mitotic cell cycle; spindle pole; cell division; mitotic prometaphase; microtubule cytoskeleton organization; M phase of mitotic cell cycle;
CEP57	6	microtubule cytoskeleton; centrosome; cytosol; protein binding; mitotic cell cycle; G2/M transition of mitotic cell cycle;
TUBGCP4	6	microtubule cytoskeleton; centrosome; cytosol; mitotic cell cycle; spindle pole; G2/M transition of mitotic cell cycle;
CDC25B	6	centrosome; cytosol; mitotic cell cycle; spindle pole; cell division; G2/M transition of mitotic cell cycle;
CEP164	6	centrosome; cytosol; protein binding; mitotic cell cycle; cell division; G2/M transition of mitotic cell cycle;
CEP250	6	centrosome; cytosol; protein binding; mitotic cell cycle; protein complex; G2/M transition of mitotic cell cycle;
CNTRL	6	centrosome; cytosol; protein binding; mitotic cell cycle; cell division; G2/M transition of mitotic cell cycle;
KIF23	6	centrosome; cytosol; protein binding; mitotic cell cycle; microtubule cytoskeleton organization; M phase of mitotic cell cycle;
TUBGCP5	6	centrosome; cytosol; mitotic cell cycle; spindle pole; microtubule cytoskeleton organization; G2/M transition of mitotic cell cycle;
TUBGCP6	6	centrosome; cytosol; mitotic cell cycle; spindle pole; microtubule cytoskeleton organization; G2/M transition of mitotic cell cycle;
INCENP	6	cytosol; protein binding; mitotic cell cycle; protein complex; mitotic prometaphase; M phase of mitotic cell cycle;
NUMA1	6	cytosol; protein binding; mitotic cell cycle; spindle pole; cell division; G2/M transition of mitotic cell cycle;
SMC1A	6	protein binding; mitotic cell cycle; cell division; mitotic prometaphase; microtubule cytoskeleton organization; M phase of mitotic cell cycle;
KIF11	5	spindle organization; cytosol; spindle pole; cell division; microtubule cytoskeleton organization;
KATNB1	5	microtubule cytoskeleton; centrosome; spindle pole; cell division; microtubule cytoskeleton organization;
PSRC1	5	microtubule cytoskeleton; cytosol; protein binding; spindle pole; cell division;
APC	5	centrosome; cytosol; protein binding; microtubule plus end; microtubule cytoskeleton organization;
CEP76	5	centrosome; cytosol; protein binding; mitotic cell cycle; G2/M transition of mitotic cell cycle;
DCTN3	5	centrosome; cytosol; protein binding; mitotic cell cycle; G2/M transition of mitotic cell cycle;
UXT	5	centrosome; gamma-tubulin complex; protein binding; centrosome organization; microtubule cytoskeleton organization;
CENPC1	5	cytosol; mitotic cell cycle; cell division; mitotic prometaphase; M phase of mitotic cell cycle;
LATS1	5	cytosol; protein binding; spindle pole; cell division; G2/M transition of mitotic cell cycle;
XPO1	5	cytosol; protein binding; mitotic cell cycle; mitotic prometaphase; M phase of mitotic cell cycle;

Genes shared at least 2 KEGG pathways with CKAP5 (count: 0)

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Region: chr11:46764598..46867847 View in gBrowse