ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	PSRC1
Symbol Alias	DDA3
Approved Name	proline/serine-rich coiled-coil 1
Name Alias	differential display and activated by p53
Location	1p13.3
Position	chr1:109822176-109825808, -
External Links	HGNC: 24472 Entrez Gene: 84722 Ensembl: ENSG00000134222 UCSC: uc001dxe.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Jarick[2012]_1	chr1:109103606-109682244 (NCBI36 / hg18)	578639	1p13.3	dup

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 17)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 17)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0007080	mitotic metaphase plate congression	Biological Process	IDA[18411309]	3
GO:0008017	microtubule binding	Molecular Function	ISS[12427559]	32
GO:0015630	microtubule cytoskeleton	Cellular Component	ISS[12427559]	34
GO:0030308	negative regulation of cell growth	Biological Process	ISS[12427559]	21
GO:0030496	midbody	Cellular Component	ISS[12427559]	14
GO:0031116	positive regulation of microtubule polymerization	Biological Process	ISS[12427559]	6
GO:0045893	positive regulation of transcription, DNA-dependent	Biological Process	ISS[12427559]	80
GO:0051301	cell division	Biological Process		58
GO:0000922	spindle pole	Cellular Component	IDA[18411309]	22
GO:0001578	microtubule bundle formation	Biological Process	ISS[12427559]	8
GO:0005515	protein binding	Molecular Function	IPI[18411309]	910
GO:0005737	cytoplasm	Cellular Component	ISS[12427559]	690
GO:0005819	spindle	Cellular Component	ISS[12427559]	29
GO:0005829	cytosol	Cellular Component	IDA[18411309]	447
GO:0005876	spindle microtubule	Cellular Component	IDA[18411309]	9
GO:0007049	cell cycle	Biological Process	ISS[12427559]	31
GO:0060236	regulation of mitotic spindle organization	Biological Process	IDA[18411309]	1

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with PSRC1 (count: 19)

Gene Symbol	Pathway Count	Pathway List
PLK1	8	microtubule binding; midbody; spindle pole; microtubule bundle formation; protein binding; spindle; cytosol; spindle microtubule;
CDK5RAP2	7	microtubule binding; positive regulation of transcription, DNA-dependent; spindle pole; microtubule bundle formation; protein binding; cytoplasm; cytosol;
KIF11	7	microtubule binding; cell division; spindle pole; cytoplasm; spindle; cytosol; spindle microtubule;
PRC1	7	microtubule binding; microtubule cytoskeleton; spindle pole; protein binding; cytoplasm; spindle; spindle microtubule;
MAPK1	7	microtubule cytoskeleton; positive regulation of transcription, DNA-dependent; protein binding; cytoplasm; spindle; cytosol; cell cycle;
NUMA1	7	cell division; spindle pole; protein binding; cytoplasm; spindle; cytosol; spindle microtubule;
CLASP1	6	microtubule binding; cell division; microtubule bundle formation; protein binding; cytosol; spindle microtubule;
CRYAB	6	microtubule binding; microtubule cytoskeleton; negative regulation of cell growth; protein binding; cytoplasm; cytosol;
KATNB1	6	microtubule binding; microtubule cytoskeleton; midbody; cell division; spindle pole; cytoplasm;
ZW10	5	mitotic metaphase plate congression; cell division; spindle pole; protein binding; cytosol;
APC	5	microtubule binding; positive regulation of microtubule polymerization; protein binding; cytoplasm; cytosol;
ARHGEF2	5	microtubule binding; cell division; protein binding; spindle; cytosol;
CEP57	5	microtubule binding; microtubule cytoskeleton; protein binding; cytoplasm; cytosol;
KIF23	5	microtubule binding; midbody; protein binding; spindle; cytosol;
MAP1S	5	microtubule binding; microtubule bundle formation; protein binding; spindle; cytosol;
CKAP5	5	microtubule cytoskeleton; cell division; spindle pole; protein binding; cytosol;
RAN	5	positive regulation of transcription, DNA-dependent; cell division; protein binding; cytoplasm; cytosol;
MAPRE1	5	cell division; protein binding; cytoplasm; spindle; cytosol;
PPP1CA	5	cell division; protein binding; cytoplasm; cytosol; cell cycle;

Genes shared at least 2 KEGG pathways with PSRC1 (count: 0)

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Region: chr1:109822176..109825808 View in gBrowse