ADHDgene Database

Hot Results

Quick Search

Keyword:
Type:

Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	CLASP1
Symbol Alias	KIAA0622, MAST1
Approved Name	cytoplasmic linker associated protein 1
Name Alias	multiple asters 1
Location	2q14.2-q14.3
Position	chr2:122095352-122407163, -
External Links	HGNC: 17088 Entrez Gene: 23332 Ensembl: ENSG00000074054 UCSC: uc002tnc.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by PBA pathway

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 32)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 2)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0051493	regulation of cytoskeleton organization	Biological Process		32
GO:0000226	microtubule cytoskeleton organization	Biological Process	IGI[15631994]	39

GO terms by database search (count: 30)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0051294	establishment of spindle orientation	Biological Process		1
GO:0051301	cell division	Biological Process		58
GO:0043515	kinetochore binding	Molecular Function	IMP[12837247]	1
GO:0051010	microtubule plus-end binding	Molecular Function	IDA[12837247]	5
GO:0010458	exit from mitosis	Biological Process	IMP[16866869]	2
GO:0030981	cortical microtubule cytoskeleton	Cellular Component	IDA[12837247]	2
GO:0007411	axon guidance	Biological Process		65
GO:0008017	microtubule binding	Molecular Function	IDA[11290329]; IMP[12837247]	32
GO:0031592	centrosomal corona	Cellular Component	IDA[16914514]	1
GO:0034453	microtubule anchoring	Biological Process	IMP[17543864]	4
GO:0031023	microtubule organizing center organization	Biological Process	IMP[17543864]	3
GO:0031111	negative regulation of microtubule polymerization or depolymerization	Biological Process	IMP[12837247]	1
GO:0005829	cytosol	Cellular Component		447
GO:0005828	kinetochore microtubule	Cellular Component	TAS[12837247]	3
GO:0005881	cytoplasmic microtubule	Cellular Component	IDA[11290329]	8
GO:0005876	spindle microtubule	Cellular Component	IDA[12837247]	9
GO:0007020	microtubule nucleation	Biological Process	IMP[17543864]	8
GO:0005938	cell cortex	Cellular Component	IDA[17113391]	26
GO:0007163	establishment or maintenance of cell polarity	Biological Process	NAS[15928712]	5
GO:0007026	negative regulation of microtubule depolymerization	Biological Process	IGI[15631994]; IMP[16866869]	7
GO:0000278	mitotic cell cycle	Biological Process		63
GO:0000236	mitotic prometaphase	Biological Process		17
GO:0000777	condensed chromosome kinetochore	Cellular Component		13
GO:0000776	kinetochore	Cellular Component	IDA[12837247]	15
GO:0005515	protein binding	Molecular Function	IPI[11290329]	910
GO:0001578	microtubule bundle formation	Biological Process	IMP[12837247]	8
GO:0005813	centrosome	Cellular Component		71
GO:0005794	Golgi apparatus	Cellular Component	IDA[15631994]	157
GO:0000086	G2/M transition of mitotic cell cycle	Biological Process		29
GO:0000087	M phase of mitotic cell cycle	Biological Process		19

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with CLASP1 (count: 45)

Gene Symbol	Pathway Count	Pathway List
CLASP2	20	cell division; microtubule plus-end binding; regulation of cytoskeleton organization; axon guidance; microtubule anchoring; microtubule organizing center organization; cytosol; kinetochore microtubule; cytoplasmic microtubule; microtubule nucleation; cell cortex; establishment or maintenance of cell polarity; negative regulation of microtubule depolymerization; mitotic cell cycle; mitotic prometaphase; condensed chromosome kinetochore; protein binding; Golgi apparatus; M phase of mitotic cell cycle; microtubule cytoskeleton organization;
MAPRE1	14	cell division; microtubule plus-end binding; regulation of cytoskeleton organization; cortical microtubule cytoskeleton; cytosol; cytoplasmic microtubule; mitotic cell cycle; mitotic prometaphase; protein binding; centrosome; Golgi apparatus; G2/M transition of mitotic cell cycle; M phase of mitotic cell cycle; microtubule cytoskeleton organization;
NDE1	12	cell division; microtubule binding; cytosol; microtubule nucleation; mitotic cell cycle; mitotic prometaphase; condensed chromosome kinetochore; kinetochore; protein binding; centrosome; G2/M transition of mitotic cell cycle; M phase of mitotic cell cycle;
PAFAH1B1	12	microtubule binding; microtubule organizing center organization; cytosol; cell cortex; mitotic cell cycle; mitotic prometaphase; kinetochore; protein binding; centrosome; G2/M transition of mitotic cell cycle; M phase of mitotic cell cycle; microtubule cytoskeleton organization;
KIF2C	11	cell division; microtubule plus-end binding; cytosol; cytoplasmic microtubule; mitotic cell cycle; mitotic prometaphase; condensed chromosome kinetochore; kinetochore; protein binding; M phase of mitotic cell cycle; microtubule cytoskeleton organization;
PLK1	11	microtubule binding; cytosol; spindle microtubule; mitotic cell cycle; mitotic prometaphase; kinetochore; protein binding; microtubule bundle formation; centrosome; G2/M transition of mitotic cell cycle; M phase of mitotic cell cycle;
APC	10	microtubule plus-end binding; regulation of cytoskeleton organization; microtubule binding; cytosol; cytoplasmic microtubule; negative regulation of microtubule depolymerization; kinetochore; protein binding; centrosome; microtubule cytoskeleton organization;
CKAP5	9	cell division; cytosol; mitotic cell cycle; mitotic prometaphase; protein binding; centrosome; G2/M transition of mitotic cell cycle; M phase of mitotic cell cycle; microtubule cytoskeleton organization;
ZW10	9	cell division; cytosol; kinetochore microtubule; mitotic cell cycle; mitotic prometaphase; condensed chromosome kinetochore; kinetochore; protein binding; M phase of mitotic cell cycle;
CDK5RAP2	9	microtubule binding; cytosol; mitotic cell cycle; protein binding; microtubule bundle formation; centrosome; Golgi apparatus; G2/M transition of mitotic cell cycle; microtubule cytoskeleton organization;
ARHGEF2	8	cell division; regulation of cytoskeleton organization; microtubule binding; cytosol; negative regulation of microtubule depolymerization; protein binding; Golgi apparatus; microtubule cytoskeleton organization;
CENPJ	8	cell division; cytosol; microtubule nucleation; mitotic cell cycle; protein binding; centrosome; G2/M transition of mitotic cell cycle; microtubule cytoskeleton organization;
SMC1A	8	cell division; mitotic cell cycle; mitotic prometaphase; condensed chromosome kinetochore; kinetochore; protein binding; M phase of mitotic cell cycle; microtubule cytoskeleton organization;
CEP57	8	microtubule binding; microtubule anchoring; cytosol; mitotic cell cycle; protein binding; centrosome; Golgi apparatus; G2/M transition of mitotic cell cycle;
TUBGCP2	8	cytosol; cytoplasmic microtubule; microtubule nucleation; mitotic cell cycle; protein binding; centrosome; G2/M transition of mitotic cell cycle; microtubule cytoskeleton organization;
CENPC1	7	cell division; cytosol; mitotic cell cycle; mitotic prometaphase; condensed chromosome kinetochore; kinetochore; M phase of mitotic cell cycle;
KIF23	7	microtubule binding; cytosol; mitotic cell cycle; protein binding; centrosome; M phase of mitotic cell cycle; microtubule cytoskeleton organization;
TUBGCP5	7	microtubule binding; cytosol; microtubule nucleation; mitotic cell cycle; centrosome; G2/M transition of mitotic cell cycle; microtubule cytoskeleton organization;
TUBGCP6	7	microtubule binding; cytosol; microtubule nucleation; mitotic cell cycle; centrosome; G2/M transition of mitotic cell cycle; microtubule cytoskeleton organization;
INCENP	7	cytosol; mitotic cell cycle; mitotic prometaphase; condensed chromosome kinetochore; kinetochore; protein binding; M phase of mitotic cell cycle;
CEP164	6	cell division; cytosol; mitotic cell cycle; protein binding; centrosome; G2/M transition of mitotic cell cycle;
CNTRL	6	cell division; cytosol; mitotic cell cycle; protein binding; centrosome; G2/M transition of mitotic cell cycle;
KATNB1	6	cell division; regulation of cytoskeleton organization; microtubule binding; negative regulation of microtubule depolymerization; centrosome; microtubule cytoskeleton organization;
NUMA1	6	cell division; cytosol; spindle microtubule; mitotic cell cycle; protein binding; G2/M transition of mitotic cell cycle;
PSRC1	6	cell division; microtubule binding; cytosol; spindle microtubule; protein binding; microtubule bundle formation;
SMC3	6	cell division; mitotic cell cycle; mitotic prometaphase; protein binding; M phase of mitotic cell cycle; microtubule cytoskeleton organization;
CEP250	6	regulation of cytoskeleton organization; cytosol; mitotic cell cycle; protein binding; centrosome; G2/M transition of mitotic cell cycle;
DCTN3	6	cytosol; mitotic cell cycle; condensed chromosome kinetochore; protein binding; centrosome; G2/M transition of mitotic cell cycle;
TUBG1	6	cytosol; mitotic cell cycle; protein binding; centrosome; G2/M transition of mitotic cell cycle; microtubule cytoskeleton organization;
XPO1	6	cytosol; mitotic cell cycle; mitotic prometaphase; kinetochore; protein binding; M phase of mitotic cell cycle;
CDC25B	5	cell division; cytosol; mitotic cell cycle; centrosome; G2/M transition of mitotic cell cycle;
CENPW	5	cell division; mitotic cell cycle; condensed chromosome kinetochore; kinetochore; protein binding;
KIF11	5	cell division; microtubule binding; cytosol; spindle microtubule; microtubule cytoskeleton organization;
LATS1	5	cell division; regulation of cytoskeleton organization; cytosol; protein binding; G2/M transition of mitotic cell cycle;
CCDC88A	5	regulation of cytoskeleton organization; microtubule binding; cytosol; Golgi apparatus; microtubule cytoskeleton organization;
MAPK1	5	regulation of cytoskeleton organization; axon guidance; cytosol; protein binding; Golgi apparatus;
MAPK3	5	regulation of cytoskeleton organization; axon guidance; cytosol; protein binding; Golgi apparatus;
MAPT	5	regulation of cytoskeleton organization; microtubule binding; cytosol; protein binding; microtubule cytoskeleton organization;
HOOK3	5	microtubule binding; protein binding; centrosome; Golgi apparatus; microtubule cytoskeleton organization;
MAP1S	5	microtubule binding; cytosol; protein binding; microtubule bundle formation; microtubule cytoskeleton organization;
MARK4	5	microtubule binding; protein binding; microtubule bundle formation; centrosome; microtubule cytoskeleton organization;
SNCA	5	microtubule binding; cytosol; cell cortex; protein binding; Golgi apparatus;
CENPN	5	cytosol; mitotic cell cycle; mitotic prometaphase; condensed chromosome kinetochore; M phase of mitotic cell cycle;
CEP76	5	cytosol; mitotic cell cycle; protein binding; centrosome; G2/M transition of mitotic cell cycle;
TUBGCP4	5	cytosol; microtubule nucleation; mitotic cell cycle; centrosome; G2/M transition of mitotic cell cycle;

Genes shared at least 2 KEGG pathways with CLASP1 (count: 0)

View in gBrowse

Region: chr2:122095352..122407163 View in gBrowse