ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	CENPW
Previous Symbol	C6orf173
Symbol Alias	CUG2
Approved Name	centromere protein W
Previous Name	chromosome 6 open reading frame 173
Name Alias	cancer-upregulated gene 2
Location	6q22.32
Position	chr6:126661253-126670021, +
External Links	HGNC: 21488 Entrez Gene: 387103 Ensembl: ENSG00000203760 UCSC: uc003qao.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
6q22-23	chr6:114600000-139000000	1 (1/0/0)

Gene related GO terms (count: 15)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 15)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0007067	mitosis	Biological Process		39
GO:0007059	chromosome segregation	Biological Process	TAS[19533040]	14
GO:0034080	CENP-A containing nucleosome assembly at centromere	Biological Process	TAS[19533040]	4
GO:0016363	nuclear matrix	Cellular Component		16
GO:0051276	chromosome organization	Biological Process		5
GO:0046982	protein heterodimerization activity	Molecular Function		68
GO:0051382	kinetochore assembly	Biological Process		2
GO:0051301	cell division	Biological Process		58
GO:0000278	mitotic cell cycle	Biological Process		63
GO:0000776	kinetochore	Cellular Component		15
GO:0000775	chromosome, centromeric region	Cellular Component	IDA[19533040]	9
GO:0003677	DNA binding	Molecular Function		220
GO:0000777	condensed chromosome kinetochore	Cellular Component		13
GO:0005730	nucleolus	Cellular Component		243
GO:0005515	protein binding	Molecular Function	IPI[19533040]	910

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with CENPW (count: 13)

Gene Symbol	Pathway Count	Pathway List
KIF2C	8	mitosis; chromosome segregation; cell division; mitotic cell cycle; kinetochore; chromosome, centromeric region; condensed chromosome kinetochore; protein binding;
SMC3	7	mitosis; nuclear matrix; protein heterodimerization activity; cell division; mitotic cell cycle; chromosome, centromeric region; protein binding;
CENPC1	7	chromosome segregation; kinetochore assembly; cell division; mitotic cell cycle; kinetochore; DNA binding; condensed chromosome kinetochore;
SMC1A	7	protein heterodimerization activity; cell division; mitotic cell cycle; kinetochore; condensed chromosome kinetochore; nucleolus; protein binding;
PTTG1	6	mitosis; chromosome segregation; chromosome organization; cell division; mitotic cell cycle; protein binding;
INCENP	6	chromosome segregation; mitotic cell cycle; kinetochore; chromosome, centromeric region; condensed chromosome kinetochore; protein binding;
CENPV	5	mitosis; cell division; kinetochore; condensed chromosome kinetochore; nucleolus;
CEP164	5	mitosis; cell division; mitotic cell cycle; nucleolus; protein binding;
RCC1	5	mitosis; chromosome segregation; cell division; nucleolus; protein binding;
NUMA1	5	nuclear matrix; cell division; mitotic cell cycle; nucleolus; protein binding;
CLASP1	5	cell division; mitotic cell cycle; kinetochore; condensed chromosome kinetochore; protein binding;
NDE1	5	cell division; mitotic cell cycle; kinetochore; condensed chromosome kinetochore; protein binding;
ZW10	5	cell division; mitotic cell cycle; kinetochore; condensed chromosome kinetochore; protein binding;

Genes shared at least 2 KEGG pathways with CENPW (count: 0)

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Region: chr6:126661253..126670021 View in gBrowse