ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	DCPS
Symbol Alias	HSPC015, HINT-5, HSL1
Approved Name	decapping enzyme, scavenger
Location	11q24
Position	chr11:126173647-126215644, 1
External Links	HGNC: 29812 Entrez Gene: 28960 Ensembl: ENSG00000110063 UCSC: uc001qdp.3
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)

Gene related GO terms (count: 17)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 17)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	biological process	TAS	4
GO:0005634	nucleus	cellular component	IDA	877
GO:0045292	mRNA cis splicing, via spliceosome	biological process	IDA[18426921]	1
GO:0036245	cellular response to menadione	biological process	IDA[16140270]	1
GO:0005730	nucleolus	cellular component	IDA	271
GO:0043069	negative regulation of programmed cell death	biological process	IDA[16140270]	4
GO:0010467	gene expression	biological process	TAS	154
GO:0050072	m7G(5')pppN diphosphatase activity	molecular function	IDA[12198172]	3
GO:0016071	mRNA metabolic process	biological process	TAS	41
GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	biological process	TAS	9
GO:0005829	cytosol	cellular component	TAS	485
GO:0000340	RNA 7-methylguanosine cap binding	molecular function	IDA[12198172]	1
GO:0016070	RNA metabolic process	biological process	TAS	54
GO:0005515	protein binding	molecular function	IPI[16140270]	1015
GO:0005739	mitochondrion	cellular component	IDA	221
GO:0005737	cytoplasm	cellular component	IDA[18441014]	781
GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA	biological process	IEA	2

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with DCPS (count: 82)

Gene Symbol	Pathway Count	Pathway List
PARN	9	nucleus; nucleolus; gene expression; mRNA metabolic process; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; cytosol; RNA metabolic process; protein binding; cytoplasm;
PATL1	8	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; gene expression; mRNA metabolic process; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; cytosol; RNA metabolic process; protein binding; deadenylation-dependent decapping of nuclear-transcribed mRNA;
LSM4	7	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; gene expression; mRNA metabolic process; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; cytosol; RNA metabolic process; protein binding;
DDX6	7	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; gene expression; mRNA metabolic process; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; cytosol; RNA metabolic process; protein binding;
RPS3	7	nucleus; gene expression; mRNA metabolic process; cytosol; RNA metabolic process; protein binding; cytoplasm;
RNPS1	7	nucleus; gene expression; mRNA metabolic process; cytosol; RNA metabolic process; protein binding; cytoplasm;
RQCD1	7	nucleus; gene expression; mRNA metabolic process; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; cytosol; RNA metabolic process; protein binding;
TNKS1BP1	7	nucleus; gene expression; mRNA metabolic process; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; cytosol; RNA metabolic process; cytoplasm;
SMG1	7	nucleus; gene expression; mRNA metabolic process; cytosol; RNA metabolic process; protein binding; cytoplasm;
PSMC3	7	nucleus; gene expression; mRNA metabolic process; cytosol; RNA metabolic process; protein binding; cytoplasm;
HSPA8	7	nucleus; nucleolus; gene expression; mRNA metabolic process; cytosol; RNA metabolic process; protein binding;
SMG7	7	nucleus; gene expression; mRNA metabolic process; cytosol; RNA metabolic process; protein binding; cytoplasm;
CNOT6	7	nucleus; gene expression; mRNA metabolic process; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; cytosol; RNA metabolic process; protein binding;
RPS9	7	nucleolus; gene expression; mRNA metabolic process; cytosol; RNA metabolic process; protein binding; cytoplasm;
XPO1	7	nucleolus; gene expression; mRNA metabolic process; cytosol; RNA metabolic process; protein binding; cytoplasm;
PAIP1	7	gene expression; mRNA metabolic process; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; cytosol; RNA metabolic process; protein binding; cytoplasm;
SRP19	6	nucleus; nucleolus; gene expression; cytosol; mitochondrion; cytoplasm;
GEMIN2	6	nucleus; gene expression; cytosol; RNA metabolic process; protein binding; cytoplasm;
IARS	6	nucleus; nucleolus; gene expression; cytosol; protein binding; cytoplasm;
NCBP1	6	nucleus; gene expression; mRNA metabolic process; cytosol; RNA metabolic process; protein binding;
MEN1	6	nucleus; nucleolus; gene expression; cytosol; protein binding; cytoplasm;
MAPK1	6	nucleus; nucleolus; cytosol; protein binding; mitochondrion; cytoplasm;
MAPK3	6	nucleus; nucleolus; gene expression; cytosol; protein binding; mitochondrion;
PDCD4	6	nucleus; nucleolus; cytosol; RNA metabolic process; protein binding; cytoplasm;
RPS10	6	nucleolus; gene expression; mRNA metabolic process; cytosol; RNA metabolic process; protein binding;
RPS25	6	nucleolus; gene expression; mRNA metabolic process; cytosol; RNA metabolic process; cytoplasm;
RPS2	6	nucleolus; gene expression; mRNA metabolic process; cytosol; RNA metabolic process; protein binding;
RPL35	6	nucleolus; gene expression; mRNA metabolic process; cytosol; RNA metabolic process; cytoplasm;
RPL14	6	gene expression; mRNA metabolic process; cytosol; RNA metabolic process; protein binding; cytoplasm;
RPS15A	6	gene expression; mRNA metabolic process; cytosol; RNA metabolic process; mitochondrion; cytoplasm;
SNCA	5	nucleus; cytosol; protein binding; mitochondrion; cytoplasm;
DDX23	5	nucleus; nucleolus; gene expression; protein binding; mitochondrion;
GSK3B	5	nucleus; nucleolus; cytosol; protein binding; cytoplasm;
PYCARD	5	nucleus; cytosol; protein binding; mitochondrion; cytoplasm;
STAP1	5	nucleus; nucleolus; protein binding; mitochondrion; cytoplasm;
MALT1	5	nucleus; nucleolus; cytosol; protein binding; cytoplasm;
EFTUD2	5	nucleus; nucleolus; gene expression; protein binding; cytoplasm;
SNRPD1	5	nucleus; gene expression; cytosol; RNA metabolic process; protein binding;
CLNS1A	5	nucleus; gene expression; cytosol; RNA metabolic process; protein binding;
DHX9	5	nucleus; nucleolus; gene expression; protein binding; cytoplasm;
TH	5	nucleus; cytosol; protein binding; mitochondrion; cytoplasm;
PGR	5	nucleus; nucleolus; gene expression; protein binding; cytoplasm;
SART1	5	nucleus; nucleolus; cytosol; protein binding; cytoplasm;
HK1	5	nucleus; nucleolus; cytosol; protein binding; mitochondrion;
ID2	5	nucleus; nucleolus; cytosol; protein binding; cytoplasm;
NEDD4L	5	nucleus; gene expression; cytosol; protein binding; cytoplasm;
PSMA8	5	nucleus; gene expression; mRNA metabolic process; cytosol; RNA metabolic process;
KARS	5	nucleus; gene expression; cytosol; mitochondrion; cytoplasm;
PARK2	5	nucleus; cytosol; protein binding; mitochondrion; cytoplasm;
YAP1	5	nucleus; gene expression; cytosol; protein binding; cytoplasm;
TCF25	5	nucleus; nucleolus; protein binding; mitochondrion; cytoplasm;
STXBP3	5	nucleus; nucleolus; cytosol; protein binding; cytoplasm;
DAXX	5	nucleus; nucleolus; cytosol; protein binding; cytoplasm;
WWOX	5	nucleus; cytosol; protein binding; mitochondrion; cytoplasm;
HNRNPA2B1	5	nucleus; nucleolus; gene expression; protein binding; cytoplasm;
CRYAB	5	nucleus; cytosol; protein binding; mitochondrion; cytoplasm;
GSTP1	5	nucleus; cytosol; protein binding; mitochondrion; cytoplasm;
SMC1A	5	nucleus; nucleolus; gene expression; protein binding; cytoplasm;
AIP	5	nucleus; nucleolus; cytosol; protein binding; cytoplasm;
DGCR8	5	nucleus; nucleolus; gene expression; protein binding; cytoplasm;
STK11	5	nucleus; cytosol; protein binding; mitochondrion; cytoplasm;
HNRNPH1	5	nucleus; nucleolus; gene expression; protein binding; cytoplasm;
MAD1L1	5	nucleus; cytosol; protein binding; mitochondrion; cytoplasm;
ATXN2	5	nucleus; nucleolus; RNA metabolic process; protein binding; cytoplasm;
CEP164	5	nucleus; nucleolus; cytosol; protein binding; cytoplasm;
ALKBH8	5	nucleus; nucleolus; cytosol; protein binding; cytoplasm;
NUMA1	5	nucleus; nucleolus; cytosol; protein binding; cytoplasm;
RBPJ	5	nucleus; nucleolus; gene expression; protein binding; cytoplasm;
CEP57	5	nucleus; nucleolus; cytosol; protein binding; cytoplasm;
FUS	5	nucleus; nucleolus; gene expression; protein binding; cytoplasm;
PAFAH1B1	5	nucleus; nucleolus; cytosol; protein binding; cytoplasm;
SSRP1	5	nucleus; nucleolus; gene expression; protein binding; cytoplasm;
PPP1CA	5	nucleus; nucleolus; cytosol; protein binding; cytoplasm;
BAIAP2	5	nucleus; nucleolus; cytosol; protein binding; cytoplasm;
PSMD7	5	gene expression; mRNA metabolic process; cytosol; RNA metabolic process; protein binding;
PSMB7	5	gene expression; mRNA metabolic process; cytosol; RNA metabolic process; protein binding;
PSME1	5	gene expression; mRNA metabolic process; cytosol; RNA metabolic process; cytoplasm;
UBB	5	gene expression; mRNA metabolic process; cytosol; RNA metabolic process; protein binding;
PSMD5	5	gene expression; mRNA metabolic process; cytosol; RNA metabolic process; protein binding;
RPL13	5	gene expression; mRNA metabolic process; cytosol; RNA metabolic process; protein binding;
RPL27A	5	gene expression; mRNA metabolic process; cytosol; RNA metabolic process; protein binding;
UBC	5	gene expression; mRNA metabolic process; cytosol; RNA metabolic process; protein binding;

Genes shared at least 2 KEGG pathways with DCPS (count: 0)

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Region: chr11:126173647..126215644 View in gBrowse