ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	RPL14
Symbol Alias	L14, hRL14, RL14, CTG-B33
Approved Name	ribosomal protein L14
Name Alias	CAG-ISL 7, "60S ribosomal protein L14"
Location	3p22-p21.2
Position	chr3:40498783-40503861, +
External Links	HGNC: 10305 Entrez Gene: 9045 Ensembl: ENSG00000188846 UCSC: uc003ckg.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by literature SNP

Gene related studies (count: 0)

Gene related SNPs (count: 1)

Literature-origin SNPs (count: 1)

rs_ID	Location	Functional Annotation	No. of Studies (significant/non-significant/trend)
rs4860	Chr12:63359783(Fwd); Chr3:40503754(Fwd)	3_prime_UTR_variant; downstream_gene_variant; nc_transcript_variant; non_coding_exon_variant	1(0/1/0)

LD-proxies (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 21)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 21)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0006414	translational elongation	Biological Process		16
GO:0006413	translational initiation	Biological Process		14
GO:0006412	translation	Biological Process	NAS[12962325]	42
GO:0006364	rRNA processing	Biological Process	IMP[18697920]	5
GO:0005829	cytosol	Cellular Component		447
GO:0005737	cytoplasm	Cellular Component		690
GO:0005515	protein binding	Molecular Function	IPI[11369516]	910
GO:0003735	structural constituent of ribosome	Molecular Function	NAS[12962325]	24
GO:0019083	viral transcription	Biological Process		13
GO:0019058	viral infectious cycle	Biological Process		15
GO:0016071	mRNA metabolic process	Biological Process		34
GO:0016070	RNA metabolic process	Biological Process		46
GO:0016032	viral reproduction	Biological Process		57
GO:0010467	gene expression	Biological Process		140
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	Biological Process		18
GO:0006415	translational termination	Biological Process		13
GO:0022625	cytosolic large ribosomal subunit	Cellular Component	IDA[12962325]	7
GO:0042273	ribosomal large subunit biogenesis	Biological Process	IMP[18697920]	2
GO:0044267	cellular protein metabolic process	Biological Process		64
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	Biological Process		16
GO:0003723	RNA binding	Molecular Function	TAS[9480843]	104

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa03010	Ribosome	14

Genes shared at least 5 GO terms with RPL14 (count: 44)

Gene Symbol	Pathway Count	Pathway List
RPL13	18	translational elongation; translational initiation; translation; cytosol; protein binding; structural constituent of ribosome; viral transcription; viral infectious cycle; mRNA metabolic process; RNA metabolic process; viral reproduction; gene expression; SRP-dependent cotranslational protein targeting to membrane; translational termination; cytosolic large ribosomal subunit; cellular protein metabolic process; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; RNA binding;
RPL12	17	translational elongation; translational initiation; translation; cytosol; structural constituent of ribosome; viral transcription; viral infectious cycle; mRNA metabolic process; RNA metabolic process; viral reproduction; gene expression; SRP-dependent cotranslational protein targeting to membrane; translational termination; cytosolic large ribosomal subunit; cellular protein metabolic process; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; RNA binding;
RPL35	17	translational elongation; translational initiation; translation; cytosol; cytoplasm; structural constituent of ribosome; viral transcription; viral infectious cycle; mRNA metabolic process; RNA metabolic process; viral reproduction; gene expression; SRP-dependent cotranslational protein targeting to membrane; translational termination; cytosolic large ribosomal subunit; cellular protein metabolic process; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;
RPL37	17	translational elongation; translational initiation; translation; cytosol; structural constituent of ribosome; viral transcription; viral infectious cycle; mRNA metabolic process; RNA metabolic process; viral reproduction; gene expression; SRP-dependent cotranslational protein targeting to membrane; translational termination; cytosolic large ribosomal subunit; cellular protein metabolic process; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; RNA binding;
RPL38	17	translational elongation; translational initiation; translation; cytosol; structural constituent of ribosome; viral transcription; viral infectious cycle; mRNA metabolic process; RNA metabolic process; viral reproduction; gene expression; SRP-dependent cotranslational protein targeting to membrane; translational termination; cytosolic large ribosomal subunit; cellular protein metabolic process; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; RNA binding;
RPS15A	17	translational elongation; translational initiation; translation; cytosol; cytoplasm; structural constituent of ribosome; viral transcription; viral infectious cycle; mRNA metabolic process; RNA metabolic process; viral reproduction; gene expression; SRP-dependent cotranslational protein targeting to membrane; translational termination; cellular protein metabolic process; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; RNA binding;
RPS25	17	translational elongation; translational initiation; translation; cytosol; cytoplasm; structural constituent of ribosome; viral transcription; viral infectious cycle; mRNA metabolic process; RNA metabolic process; viral reproduction; gene expression; SRP-dependent cotranslational protein targeting to membrane; translational termination; cellular protein metabolic process; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; RNA binding;
RPS3	17	translational elongation; translational initiation; translation; cytosol; cytoplasm; protein binding; structural constituent of ribosome; viral transcription; viral infectious cycle; mRNA metabolic process; RNA metabolic process; viral reproduction; gene expression; SRP-dependent cotranslational protein targeting to membrane; translational termination; cellular protein metabolic process; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;
RPS9	17	translational elongation; translational initiation; translation; cytosol; cytoplasm; protein binding; structural constituent of ribosome; viral transcription; viral infectious cycle; mRNA metabolic process; RNA metabolic process; viral reproduction; gene expression; SRP-dependent cotranslational protein targeting to membrane; translational termination; cellular protein metabolic process; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;
FAU	16	translational elongation; translational initiation; translation; cytosol; structural constituent of ribosome; viral transcription; viral infectious cycle; mRNA metabolic process; RNA metabolic process; viral reproduction; gene expression; SRP-dependent cotranslational protein targeting to membrane; translational termination; cellular protein metabolic process; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; RNA binding;
RPL37A	16	translational elongation; translational initiation; translation; cytosol; structural constituent of ribosome; viral transcription; viral infectious cycle; mRNA metabolic process; RNA metabolic process; viral reproduction; gene expression; SRP-dependent cotranslational protein targeting to membrane; translational termination; cytosolic large ribosomal subunit; cellular protein metabolic process; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;
RPS12	15	translational elongation; translational initiation; translation; cytosol; structural constituent of ribosome; viral transcription; viral infectious cycle; mRNA metabolic process; RNA metabolic process; viral reproduction; gene expression; SRP-dependent cotranslational protein targeting to membrane; translational termination; cellular protein metabolic process; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;
XPO1	9	cytosol; cytoplasm; protein binding; viral infectious cycle; mRNA metabolic process; RNA metabolic process; viral reproduction; gene expression; RNA binding;
NCBP1	8	cytosol; protein binding; mRNA metabolic process; RNA metabolic process; viral reproduction; gene expression; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; RNA binding;
EIF2B1	7	translational initiation; translation; cytosol; cytoplasm; protein binding; gene expression; cellular protein metabolic process;
PSMC3	7	cytosol; cytoplasm; protein binding; mRNA metabolic process; RNA metabolic process; viral reproduction; gene expression;
SMG1	7	cytosol; cytoplasm; protein binding; mRNA metabolic process; RNA metabolic process; gene expression; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;
SMG7	7	cytosol; cytoplasm; protein binding; mRNA metabolic process; RNA metabolic process; gene expression; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;
EEF1D	6	translational elongation; translation; cytosol; protein binding; gene expression; cellular protein metabolic process;
EEF1G	6	translational elongation; translation; cytosol; protein binding; gene expression; cellular protein metabolic process;
SRP19	6	translation; cytosol; cytoplasm; gene expression; SRP-dependent cotranslational protein targeting to membrane; cellular protein metabolic process;
CNOT6	6	cytosol; protein binding; mRNA metabolic process; RNA metabolic process; gene expression; RNA binding;
DCPS	6	cytosol; cytoplasm; protein binding; mRNA metabolic process; RNA metabolic process; gene expression;
DDX6	6	cytosol; protein binding; mRNA metabolic process; RNA metabolic process; gene expression; RNA binding;
LSM4	6	cytosol; protein binding; mRNA metabolic process; RNA metabolic process; gene expression; RNA binding;
PATL1	6	cytosol; protein binding; mRNA metabolic process; RNA metabolic process; gene expression; RNA binding;
PSMB7	6	cytosol; protein binding; mRNA metabolic process; RNA metabolic process; viral reproduction; gene expression;
PSMD5	6	cytosol; protein binding; mRNA metabolic process; RNA metabolic process; viral reproduction; gene expression;
PSMD7	6	cytosol; protein binding; mRNA metabolic process; RNA metabolic process; viral reproduction; gene expression;
PSME1	6	cytosol; cytoplasm; mRNA metabolic process; RNA metabolic process; viral reproduction; gene expression;
RAN	6	cytosol; cytoplasm; protein binding; viral infectious cycle; viral reproduction; gene expression;
UBB	6	cytosol; protein binding; mRNA metabolic process; RNA metabolic process; viral reproduction; gene expression;
UBC	6	cytosol; protein binding; mRNA metabolic process; RNA metabolic process; viral reproduction; gene expression;
IGF2BP3	5	translation; cytosol; cytoplasm; protein binding; RNA binding;
SARS	5	translation; cytosol; cytoplasm; gene expression; RNA binding;
SEC61B	5	translation; protein binding; gene expression; SRP-dependent cotranslational protein targeting to membrane; cellular protein metabolic process;
HSPA8	5	cytosol; protein binding; mRNA metabolic process; RNA metabolic process; gene expression;
PDCD4	5	cytosol; cytoplasm; protein binding; RNA metabolic process; RNA binding;
PSMA8	5	cytosol; mRNA metabolic process; RNA metabolic process; viral reproduction; gene expression;
PSME2	5	cytosol; mRNA metabolic process; RNA metabolic process; viral reproduction; gene expression;
RQCD1	5	cytosol; protein binding; mRNA metabolic process; RNA metabolic process; gene expression;
SNRPD1	5	cytosol; protein binding; RNA metabolic process; gene expression; RNA binding;
SNRPG	5	cytosol; protein binding; RNA metabolic process; gene expression; RNA binding;
TNKS1BP1	5	cytosol; cytoplasm; mRNA metabolic process; RNA metabolic process; gene expression;

Genes shared at least 2 KEGG pathways with RPL14 (count: 0)

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Region: chr3:40498783..40503861 View in gBrowse