ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	ALKBH8
Symbol Alias	MGC10235
Approved Name	alkB, alkylation repair homolog 8 (E. coli)
Location	11q22.3
Position	chr11:107373452-107436472, -
External Links	HGNC: 25189 Entrez Gene: 91801 Ensembl: ENSG00000137760 UCSC: uc009yxp.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 2)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)
11q22	chr11:97200000-110400000	1 (1/0/0)

Gene related GO terms (count: 12)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 12)

ID	Name	Type	No. of Genes in ADHDgene
GO:0016706	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors	Molecular Function	2
GO:0005730	nucleolus	Cellular Component	243
GO:0016300	tRNA (uracil) methyltransferase activity	Molecular Function	1
GO:0005634	nucleus	Cellular Component	770
GO:0015630	microtubule cytoskeleton	Cellular Component	34
GO:0005829	cytosol	Cellular Component	447
GO:0006974	response to DNA damage stimulus	Biological Process	37
GO:0005737	cytoplasm	Cellular Component	690
GO:0046872	metal ion binding	Molecular Function	170
GO:0005515	protein binding	Molecular Function	910
GO:0030488	tRNA methylation	Biological Process	1
GO:0003723	RNA binding	Molecular Function	104

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with ALKBH8 (count: 50)

Gene Symbol	Pathway Count	Pathway List
MAPK1	7	nucleolus; nucleus; microtubule cytoskeleton; cytosol; response to DNA damage stimulus; cytoplasm; protein binding;
CEP57	6	nucleolus; nucleus; microtubule cytoskeleton; cytosol; cytoplasm; protein binding;
DGCR8	6	nucleolus; nucleus; microtubule cytoskeleton; cytoplasm; metal ion binding; protein binding;
MAPK3	6	nucleolus; nucleus; microtubule cytoskeleton; cytosol; response to DNA damage stimulus; protein binding;
MEN1	6	nucleolus; nucleus; cytosol; response to DNA damage stimulus; cytoplasm; protein binding;
PDCD4	6	nucleolus; nucleus; cytosol; cytoplasm; protein binding; RNA binding;
PPP1CA	6	nucleolus; nucleus; cytosol; cytoplasm; metal ion binding; protein binding;
CRYAB	6	nucleus; microtubule cytoskeleton; cytosol; cytoplasm; metal ion binding; protein binding;
AATF	5	nucleolus; nucleus; response to DNA damage stimulus; cytoplasm; protein binding;
AIP	5	nucleolus; nucleus; cytosol; cytoplasm; protein binding;
ATXN2	5	nucleolus; nucleus; cytoplasm; protein binding; RNA binding;
BAIAP2	5	nucleolus; nucleus; cytosol; cytoplasm; protein binding;
CEP164	5	nucleolus; nucleus; cytosol; cytoplasm; protein binding;
CHD1L	5	nucleolus; nucleus; response to DNA damage stimulus; cytoplasm; protein binding;
DAXX	5	nucleolus; nucleus; cytosol; cytoplasm; protein binding;
DCPS	5	nucleolus; nucleus; cytosol; cytoplasm; protein binding;
FUS	5	nucleolus; nucleus; cytoplasm; protein binding; RNA binding;
GSK3B	5	nucleolus; nucleus; cytosol; cytoplasm; protein binding;
HNRNPA2B1	5	nucleolus; nucleus; cytoplasm; protein binding; RNA binding;
HNRNPH1	5	nucleolus; nucleus; cytoplasm; protein binding; RNA binding;
IARS	5	nucleolus; nucleus; cytosol; cytoplasm; protein binding;
ID2	5	nucleolus; nucleus; cytosol; cytoplasm; protein binding;
KAT5	5	nucleolus; nucleus; cytosol; metal ion binding; protein binding;
MALT1	5	nucleolus; nucleus; cytosol; cytoplasm; protein binding;
MPHOSPH6	5	nucleolus; nucleus; cytoplasm; protein binding; RNA binding;
NOL8	5	nucleolus; nucleus; cytoplasm; protein binding; RNA binding;
NUMA1	5	nucleolus; nucleus; cytosol; cytoplasm; protein binding;
PAFAH1B1	5	nucleolus; nucleus; cytosol; cytoplasm; protein binding;
PRC1	5	nucleolus; nucleus; microtubule cytoskeleton; cytoplasm; protein binding;
PSPC1	5	nucleolus; nucleus; cytoplasm; protein binding; RNA binding;
RAD9A	5	nucleolus; nucleus; response to DNA damage stimulus; cytoplasm; protein binding;
RBM4	5	nucleolus; nucleus; cytoplasm; protein binding; RNA binding;
RFWD2	5	nucleolus; nucleus; cytosol; cytoplasm; protein binding;
SART1	5	nucleolus; nucleus; cytosol; cytoplasm; protein binding;
STXBP3	5	nucleolus; nucleus; cytosol; cytoplasm; protein binding;
XPO1	5	nucleolus; cytosol; cytoplasm; protein binding; RNA binding;
ZFR	5	nucleolus; nucleus; cytoplasm; protein binding; RNA binding;
APC	5	nucleus; cytosol; response to DNA damage stimulus; cytoplasm; protein binding;
BARD1	5	nucleus; response to DNA damage stimulus; cytoplasm; protein binding; RNA binding;
CNOT6	5	nucleus; cytosol; metal ion binding; protein binding; RNA binding;
EGLN3	5	nucleus; cytosol; response to DNA damage stimulus; cytoplasm; protein binding;
IGF2BP3	5	nucleus; cytosol; cytoplasm; protein binding; RNA binding;
IRF7	5	nucleus; cytosol; response to DNA damage stimulus; cytoplasm; protein binding;
KARS	5	nucleus; microtubule cytoskeleton; cytosol; cytoplasm; metal ion binding;
PDE2A	5	nucleus; cytosol; cytoplasm; metal ion binding; protein binding;
PRKD1	5	nucleus; cytosol; cytoplasm; metal ion binding; protein binding;
RPS3	5	nucleus; cytosol; response to DNA damage stimulus; cytoplasm; protein binding;
SMG1	5	nucleus; cytosol; cytoplasm; metal ion binding; protein binding;
YAP1	5	nucleus; cytosol; response to DNA damage stimulus; cytoplasm; protein binding;
IREB2	5	cytosol; cytoplasm; metal ion binding; protein binding; RNA binding;

Genes shared at least 2 KEGG pathways with ALKBH8 (count: 0)

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Region: chr11:107373452..107436472 View in gBrowse