ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	CHD1L
Symbol Alias	ALC1
Approved Name	chromodomain helicase DNA binding protein 1-like
Location	1q21.1
Position	chr1:146714291-146767443, +
External Links	HGNC: 1916 Entrez Gene: 9557 Ensembl: ENSG00000131778 UCSC: uc001epm.3
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Jarick[2012]_2	chr1:144943150-146293282 (NCBI36 / hg18)	1350133	1q21.1	del

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 14)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 14)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0003677	DNA binding	Molecular Function		220
GO:0004003	ATP-dependent DNA helicase activity	Molecular Function	TAS[19661379]	4
GO:0000166	nucleotide binding	Molecular Function	IDA[19661379]	73
GO:0005634	nucleus	Cellular Component		770
GO:0005730	nucleolus	Cellular Component		243
GO:0005515	protein binding	Molecular Function	IPI[19661379]	910
GO:0005524	ATP binding	Molecular Function		228
GO:0006200	ATP catabolic process	Biological Process	IMP[19661379]	6
GO:0006281	DNA repair	Biological Process	TAS[19661379]	62
GO:0005737	cytoplasm	Cellular Component		690
GO:0005886	plasma membrane	Cellular Component		772
GO:0016887	ATPase activity	Molecular Function	IMP[19661379]	14
GO:0006974	response to DNA damage stimulus	Biological Process	IDA[19661379]	37
GO:0006338	chromatin remodeling	Biological Process	IDA[19661379]	10

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with CHD1L (count: 76)

Gene Symbol	Pathway Count	Pathway List
XRCC5	8	DNA binding; ATP-dependent DNA helicase activity; nucleus; nucleolus; protein binding; ATP binding; DNA repair; cytoplasm;
DHX9	7	DNA binding; ATP-dependent DNA helicase activity; nucleus; nucleolus; protein binding; ATP binding; cytoplasm;
MAPK1	7	DNA binding; nucleus; nucleolus; protein binding; ATP binding; cytoplasm; response to DNA damage stimulus;
MRE11A	7	DNA binding; ATP-dependent DNA helicase activity; nucleus; nucleolus; protein binding; DNA repair; response to DNA damage stimulus;
MEN1	7	nucleus; nucleolus; protein binding; DNA repair; cytoplasm; response to DNA damage stimulus; chromatin remodeling;
FUS	6	DNA binding; nucleotide binding; nucleus; nucleolus; protein binding; cytoplasm;
IGHMBP2	6	DNA binding; nucleus; protein binding; ATP binding; DNA repair; cytoplasm;
SSRP1	6	DNA binding; nucleus; nucleolus; protein binding; DNA repair; cytoplasm;
ABCC1	6	nucleus; nucleolus; ATP binding; ATP catabolic process; plasma membrane; ATPase activity;
GSK3B	6	nucleus; nucleolus; protein binding; ATP binding; cytoplasm; plasma membrane;
RAD9A	6	nucleus; nucleolus; protein binding; DNA repair; cytoplasm; response to DNA damage stimulus;
SMC1A	6	nucleus; nucleolus; protein binding; ATP binding; DNA repair; cytoplasm;
ATM	5	DNA binding; protein binding; ATP binding; DNA repair; response to DNA damage stimulus;
ATXN1	5	DNA binding; nucleus; nucleolus; protein binding; cytoplasm;
BCLAF1	5	DNA binding; nucleus; nucleolus; protein binding; cytoplasm;
DDB1	5	DNA binding; nucleus; protein binding; DNA repair; cytoplasm;
FEN1	5	DNA binding; nucleus; nucleolus; protein binding; DNA repair;
H2AFX	5	DNA binding; nucleus; protein binding; DNA repair; response to DNA damage stimulus;
HINFP	5	DNA binding; nucleus; nucleolus; protein binding; DNA repair;
IRF7	5	DNA binding; nucleus; protein binding; cytoplasm; response to DNA damage stimulus;
KIF22	5	DNA binding; nucleus; ATP binding; DNA repair; cytoplasm;
NFRKB	5	DNA binding; nucleus; nucleolus; protein binding; DNA repair;
PGR	5	DNA binding; nucleus; nucleolus; protein binding; cytoplasm;
PRPF19	5	DNA binding; nucleus; protein binding; DNA repair; cytoplasm;
RBPJ	5	DNA binding; nucleus; nucleolus; protein binding; cytoplasm;
TCF25	5	DNA binding; nucleus; nucleolus; protein binding; cytoplasm;
ZFR	5	DNA binding; nucleus; nucleolus; protein binding; cytoplasm;
HNRNPA2B1	5	nucleotide binding; nucleus; nucleolus; protein binding; cytoplasm;
HNRNPH1	5	nucleotide binding; nucleus; nucleolus; protein binding; cytoplasm;
NOL8	5	nucleotide binding; nucleus; nucleolus; protein binding; cytoplasm;
PSPC1	5	nucleotide binding; nucleus; nucleolus; protein binding; cytoplasm;
RBM14	5	nucleotide binding; nucleus; nucleolus; protein binding; DNA repair;
RBM4	5	nucleotide binding; nucleus; nucleolus; protein binding; cytoplasm;
WWOX	5	nucleotide binding; nucleus; protein binding; cytoplasm; plasma membrane;
AATF	5	nucleus; nucleolus; protein binding; cytoplasm; response to DNA damage stimulus;
AIP	5	nucleus; nucleolus; protein binding; cytoplasm; plasma membrane;
ALKBH8	5	nucleus; nucleolus; protein binding; cytoplasm; response to DNA damage stimulus;
APBB1	5	nucleus; protein binding; cytoplasm; plasma membrane; response to DNA damage stimulus;
APC	5	nucleus; protein binding; cytoplasm; plasma membrane; response to DNA damage stimulus;
BAIAP2	5	nucleus; nucleolus; protein binding; cytoplasm; plasma membrane;
BARD1	5	nucleus; protein binding; DNA repair; cytoplasm; response to DNA damage stimulus;
CDCA5	5	nucleus; nucleolus; protein binding; cytoplasm; plasma membrane;
CEP164	5	nucleus; nucleolus; protein binding; DNA repair; cytoplasm;
CHEK1	5	nucleus; protein binding; ATP binding; DNA repair; response to DNA damage stimulus;
COG3	5	nucleus; nucleolus; protein binding; cytoplasm; plasma membrane;
DDX23	5	nucleus; nucleolus; protein binding; ATP binding; plasma membrane;
EHD3	5	nucleus; protein binding; ATP binding; cytoplasm; plasma membrane;
FLT4	5	nucleus; protein binding; ATP binding; cytoplasm; plasma membrane;
FRK	5	nucleus; protein binding; ATP binding; cytoplasm; plasma membrane;
HERC2	5	nucleus; protein binding; DNA repair; cytoplasm; response to DNA damage stimulus;
HSPA5	5	nucleus; protein binding; ATP binding; ATP catabolic process; ATPase activity;
HSPA8	5	nucleus; nucleolus; protein binding; ATP binding; plasma membrane;
IARS	5	nucleus; nucleolus; protein binding; ATP binding; cytoplasm;
MALT1	5	nucleus; nucleolus; protein binding; cytoplasm; plasma membrane;
MAPK3	5	nucleus; nucleolus; protein binding; ATP binding; response to DNA damage stimulus;
MMS19	5	nucleus; protein binding; DNA repair; cytoplasm; response to DNA damage stimulus;
NCOA6	5	nucleus; nucleolus; protein binding; DNA repair; response to DNA damage stimulus;
NF2	5	nucleus; nucleolus; protein binding; cytoplasm; plasma membrane;
PRC1	5	nucleus; nucleolus; protein binding; cytoplasm; plasma membrane;
PRKCB	5	nucleus; protein binding; ATP binding; cytoplasm; plasma membrane;
PRKD1	5	nucleus; protein binding; ATP binding; cytoplasm; plasma membrane;
RAD1	5	nucleus; nucleolus; protein binding; DNA repair; response to DNA damage stimulus;
RAD23B	5	nucleus; nucleolus; protein binding; DNA repair; cytoplasm;
RNF40	5	nucleus; nucleolus; protein binding; cytoplasm; plasma membrane;
RPS6KA4	5	nucleus; nucleolus; protein binding; ATP binding; cytoplasm;
RRP8	5	nucleus; nucleolus; protein binding; cytoplasm; plasma membrane;
SAP18	5	nucleus; nucleolus; protein binding; cytoplasm; plasma membrane;
SMC2	5	nucleus; protein binding; ATP binding; DNA repair; cytoplasm;
SMC3	5	nucleus; protein binding; ATP binding; DNA repair; cytoplasm;
SMG1	5	nucleus; protein binding; ATP binding; DNA repair; cytoplasm;
STXBP3	5	nucleus; nucleolus; protein binding; cytoplasm; plasma membrane;
TAOK2	5	nucleus; nucleolus; ATP binding; cytoplasm; response to DNA damage stimulus;
TP53BP1	5	nucleus; protein binding; DNA repair; cytoplasm; response to DNA damage stimulus;
TRIP12	5	nucleus; protein binding; DNA repair; cytoplasm; response to DNA damage stimulus;
USP28	5	nucleus; nucleolus; protein binding; DNA repair; response to DNA damage stimulus;
ATP8B1	5	protein binding; ATP binding; ATP catabolic process; plasma membrane; ATPase activity;

Genes shared at least 2 KEGG pathways with CHD1L (count: 0)

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Region: chr1:146714291..146767443 View in gBrowse