ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	CHD1L
Symbol Alias	ALC1
Approved Name	chromodomain helicase DNA binding protein 1-like
Location	1q21.1
Position	chr1:146714291-146767443, 1
External Links	HGNC: 1916 Entrez Gene: 9557 Ensembl: ENSG00000131778 UCSC: uc001epm.5
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Jarick[2012]_2	chr1:144943150-146293282 (NCBI36 / hg18)	1350133	1q21.1	del

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 14)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 14)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005524	ATP binding	molecular function	IEA	265
GO:0005730	nucleolus	cellular component	IDA	271
GO:0006281	DNA repair	biological process	TAS[19661379]	70
GO:0006338	chromatin remodeling	biological process	IDA[19661379]	11
GO:0003677	DNA binding	molecular function	IEA	257
GO:0005634	nucleus	cellular component	IDA	877
GO:0006200	ATP catabolic process	biological process	IMP[19661379]	9
GO:0005737	cytoplasm	cellular component	IDA	781
GO:0016887	ATPase activity	molecular function	IMP[19661379]	18
GO:0006974	response to DNA damage stimulus	biological process	IDA[19661379]	41
GO:0004003	ATP-dependent DNA helicase activity	molecular function	TAS[19661379]	4
GO:0000166	nucleotide binding	molecular function	IDA[19661379]	83
GO:0005515	protein binding	molecular function	IPI[19661379]	1015
GO:0005886	plasma membrane	cellular component	IDA	839

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with CHD1L (count: 83)

Gene Symbol	Pathway Count	Pathway List
XRCC5	8	ATP binding; nucleolus; DNA repair; DNA binding; nucleus; cytoplasm; ATP-dependent DNA helicase activity; protein binding;
DHX9	7	ATP binding; nucleolus; DNA binding; nucleus; cytoplasm; ATP-dependent DNA helicase activity; protein binding;
MAPK1	7	ATP binding; nucleolus; DNA binding; nucleus; cytoplasm; response to DNA damage stimulus; protein binding;
MRE11A	7	nucleolus; DNA repair; DNA binding; nucleus; response to DNA damage stimulus; ATP-dependent DNA helicase activity; protein binding;
MEN1	7	nucleolus; DNA repair; chromatin remodeling; nucleus; cytoplasm; response to DNA damage stimulus; protein binding;
SMC1A	6	ATP binding; nucleolus; DNA repair; nucleus; cytoplasm; protein binding;
IGHMBP2	6	ATP binding; DNA repair; DNA binding; nucleus; cytoplasm; protein binding;
GSK3B	6	ATP binding; nucleolus; nucleus; cytoplasm; protein binding; plasma membrane;
ABCC1	6	ATP binding; nucleolus; nucleus; ATP catabolic process; ATPase activity; plasma membrane;
FUS	6	nucleolus; DNA binding; nucleus; cytoplasm; nucleotide binding; protein binding;
SSRP1	6	nucleolus; DNA repair; DNA binding; nucleus; cytoplasm; protein binding;
RAD9A	6	nucleolus; DNA repair; nucleus; cytoplasm; response to DNA damage stimulus; protein binding;
EHD3	5	ATP binding; nucleus; cytoplasm; protein binding; plasma membrane;
FLT4	5	ATP binding; nucleus; cytoplasm; protein binding; plasma membrane;
ATM	5	ATP binding; DNA repair; DNA binding; response to DNA damage stimulus; protein binding;
NUBP1	5	ATP binding; cytoplasm; nucleotide binding; protein binding; plasma membrane;
TAOK2	5	ATP binding; nucleolus; nucleus; cytoplasm; response to DNA damage stimulus;
HSPA5	5	ATP binding; nucleus; ATP catabolic process; ATPase activity; protein binding;
RPS6KA4	5	ATP binding; nucleolus; nucleus; cytoplasm; protein binding;
KIF22	5	ATP binding; DNA repair; DNA binding; nucleus; cytoplasm;
STK11	5	ATP binding; nucleus; cytoplasm; response to DNA damage stimulus; protein binding;
FRK	5	ATP binding; nucleus; cytoplasm; protein binding; plasma membrane;
HSPA8	5	ATP binding; nucleolus; nucleus; protein binding; plasma membrane;
DDX23	5	ATP binding; nucleolus; nucleus; protein binding; plasma membrane;
SMC3	5	ATP binding; DNA repair; nucleus; cytoplasm; protein binding;
ATP8B1	5	ATP binding; ATP catabolic process; ATPase activity; protein binding; plasma membrane;
SMG1	5	ATP binding; DNA repair; nucleus; cytoplasm; protein binding;
SMC2	5	ATP binding; DNA repair; nucleus; cytoplasm; protein binding;
CHEK1	5	ATP binding; DNA repair; nucleus; response to DNA damage stimulus; protein binding;
PRKD1	5	ATP binding; nucleus; cytoplasm; protein binding; plasma membrane;
MAPK3	5	ATP binding; nucleolus; nucleus; response to DNA damage stimulus; protein binding;
NUBP2	5	ATP binding; nucleus; cytoplasm; nucleotide binding; protein binding;
ERCC6L2	5	ATP binding; DNA repair; DNA binding; nucleus; cytoplasm;
IARS	5	ATP binding; nucleolus; nucleus; cytoplasm; protein binding;
CEP164	5	nucleolus; DNA repair; nucleus; cytoplasm; protein binding;
PARN	5	nucleolus; nucleus; cytoplasm; nucleotide binding; protein binding;
INIP	5	nucleolus; DNA repair; nucleus; response to DNA damage stimulus; protein binding;
MALT1	5	nucleolus; nucleus; cytoplasm; protein binding; plasma membrane;
STXBP3	5	nucleolus; nucleus; cytoplasm; protein binding; plasma membrane;
RBM14	5	nucleolus; DNA repair; nucleus; nucleotide binding; protein binding;
AATF	5	nucleolus; nucleus; cytoplasm; response to DNA damage stimulus; protein binding;
AIP	5	nucleolus; nucleus; cytoplasm; protein binding; plasma membrane;
FEN1	5	nucleolus; DNA repair; DNA binding; nucleus; protein binding;
RAD1	5	nucleolus; DNA repair; nucleus; response to DNA damage stimulus; protein binding;
ATXN1	5	nucleolus; DNA binding; nucleus; cytoplasm; protein binding;
PGR	5	nucleolus; DNA binding; nucleus; cytoplasm; protein binding;
NCOA6	5	nucleolus; DNA repair; nucleus; response to DNA damage stimulus; protein binding;
HINFP	5	nucleolus; DNA repair; DNA binding; nucleus; protein binding;
NF2	5	nucleolus; nucleus; cytoplasm; protein binding; plasma membrane;
PNN	5	nucleolus; DNA binding; nucleus; cytoplasm; plasma membrane;
COG3	5	nucleolus; nucleus; cytoplasm; protein binding; plasma membrane;
CDCA5	5	nucleolus; nucleus; cytoplasm; protein binding; plasma membrane;
ALKBH8	5	nucleolus; nucleus; cytoplasm; response to DNA damage stimulus; protein binding;
USP28	5	nucleolus; DNA repair; nucleus; response to DNA damage stimulus; protein binding;
RNF40	5	nucleolus; nucleus; cytoplasm; protein binding; plasma membrane;
TCF25	5	nucleolus; DNA binding; nucleus; cytoplasm; protein binding;
HNRNPH1	5	nucleolus; nucleus; cytoplasm; nucleotide binding; protein binding;
PRC1	5	nucleolus; nucleus; cytoplasm; protein binding; plasma membrane;
RRP8	5	nucleolus; nucleus; cytoplasm; protein binding; plasma membrane;
RAD23B	5	nucleolus; DNA repair; nucleus; cytoplasm; protein binding;
HNRNPA2B1	5	nucleolus; nucleus; cytoplasm; nucleotide binding; protein binding;
RBPJ	5	nucleolus; DNA binding; nucleus; cytoplasm; protein binding;
NFRKB	5	nucleolus; DNA repair; DNA binding; nucleus; protein binding;
ZFR	5	nucleolus; DNA binding; nucleus; cytoplasm; protein binding;
BCLAF1	5	nucleolus; DNA binding; nucleus; cytoplasm; protein binding;
BAIAP2	5	nucleolus; nucleus; cytoplasm; protein binding; plasma membrane;
RBM4	5	nucleolus; nucleus; cytoplasm; nucleotide binding; protein binding;
NOL8	5	nucleolus; nucleus; cytoplasm; nucleotide binding; protein binding;
PSPC1	5	nucleolus; nucleus; cytoplasm; nucleotide binding; protein binding;
SAP18	5	nucleolus; nucleus; cytoplasm; protein binding; plasma membrane;
HERC2	5	DNA repair; nucleus; cytoplasm; response to DNA damage stimulus; protein binding;
BARD1	5	DNA repair; nucleus; cytoplasm; response to DNA damage stimulus; protein binding;
MMS19	5	DNA repair; nucleus; cytoplasm; response to DNA damage stimulus; protein binding;
TRIP12	5	DNA repair; nucleus; cytoplasm; response to DNA damage stimulus; protein binding;
PRPF19	5	DNA repair; DNA binding; nucleus; cytoplasm; protein binding;
DDB1	5	DNA repair; DNA binding; nucleus; cytoplasm; protein binding;
H2AFX	5	DNA repair; DNA binding; nucleus; response to DNA damage stimulus; protein binding;
TP53BP1	5	DNA repair; nucleus; cytoplasm; response to DNA damage stimulus; protein binding;
IRF7	5	DNA binding; nucleus; cytoplasm; response to DNA damage stimulus; protein binding;
APC	5	nucleus; cytoplasm; response to DNA damage stimulus; protein binding; plasma membrane;
APBB1	5	nucleus; cytoplasm; response to DNA damage stimulus; protein binding; plasma membrane;
WWOX	5	nucleus; cytoplasm; nucleotide binding; protein binding; plasma membrane;
PICK1	5	ATP catabolic process; cytoplasm; ATPase activity; protein binding; plasma membrane;

Genes shared at least 2 KEGG pathways with CHD1L (count: 0)

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Region: chr1:146714291..146767443 View in gBrowse