ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

Gene Report

Basic Info
Approved Symbol PARK2
Symbol Alias PDJ, AR-JP, parkin
Approved Name parkin RBR E3 ubiquitin protein ligase
Previous Name "Parkinson disease (autosomal recessive, juvenile) 2, parkin", "parkinson protein 2, E3 ubiquitin protein ligase (parkin)"
Name Alias "E3 ubiquitin ligase"
Location 6q25.2-q27
Position chr6:161768452-163148803, -1
External Links HGNC: 8607
Entrez Gene: 5071
Ensembl: ENSG00000185345
UCSC: uc003qtx.4
No. of Studies 1 (significant: 1; non-significant: 0; trend: 0)
Source Literature-origin; Mapped by CNV

Gene related studies (count: 1)
Reference Statistical Values/Author Comments Result of Statistical Analysis
Jarick, I., 2012 Rare CNVs within PARK2 were identified with a significantly higher prevalence in ADHD patients than in controls (P=2.8E-4 after empirical correction for genome-wide testing). In the replication sample, CNVs at the PARK2 locus were found in four additional ADHD patients and one additional control (P=4.3E-2). Significant

Gene related SNPs (count: 0)

Gene related CNVs (count: 10)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 36)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 36)

Gene related KEGG pathways (count: 3)

Genes shared at least 5 GO terms with PARK2 (count: 89)

Genes shared at least 2 KEGG pathways with PARK2 (count: 2)

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Region: chr6:161768452..163148803 View in gBrowse
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