ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

Gene Report

Basic Info
Approved Symbol PARK2
Symbol Alias PDJ, AR-JP, parkin
Approved Name parkinson protein 2, E3 ubiquitin protein ligase (parkin)
Previous Name Parkinson disease (autosomal recessive, juvenile) 2, parkin
Name Alias E3 ubiquitin ligase
Location 6q25.2-q27
Position chr6:161768452-163148834, -
External Links HGNC: 8607
Entrez Gene: 5071
Ensembl: ENSG00000185345
UCSC: uc003qtx.3
No. of Studies 1 (significant: 1; non-significant: 0; trend: 0)
Source Literature-origin; Mapped by CNV

Gene related studies (count: 1)
Reference Statistical Values/Author Comments Result of Statistical Analysis
Jarick, I., 2012 Rare CNVs within PARK2 were identified with a significantly higher prevalence in ADHD patients than in controls (P=2.8E-4 after empirical correction for genome-wide testing). In the replication sample, CNVs at the PARK2 locus were found in four additional ADHD patients and one additional control (P=4.3E-2). Significant

Gene related SNPs (count: 0)

Gene related CNVs (count: 10)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 36)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 36)

Gene related KEGG pathways (count: 3)

Genes shared at least 5 GO terms with PARK2 (count: 78)

Genes shared at least 2 KEGG pathways with PARK2 (count: 2)

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Region: chr6:161768452..163148834 View in gBrowse
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