Gene Report
Basic Info
Approved Symbol |
FBXO4
|
Symbol Alias |
FBX4 |
Approved Name |
F-box protein 4 |
Previous Name |
F-box only protein 4 |
Location |
5p12 |
Position |
chr5:41925356-41941845, + |
External Links |
HGNC: 13583
Entrez Gene: 26272
Ensembl: ENSG00000151876
UCSC: uc003jmq.2
|
No. of Studies |
0 (significant: 0; non-significant: 0; trend: 0) |
Source |
Mapped by significant region |
Gene related studies (count: 0)
Gene related SNPs (count: 0)
Gene related CNVs (count: 0)
Gene related other variant (count: 0)
Gene related regions (count: 1)
Gene related GO terms (count: 12)
Gene related KEGG pathways (count: 1)
ID |
Name |
No. of Genes in ADHDgene |
Brief Description |
hsa04120 |
Ubiquitin mediated proteolysis |
29 |
Protein ubiquitination plays an important role in eukaryotic......
Protein ubiquitination plays an important role in eukaryotic cellular processes. It mainly functions as a signal for 26S proteasome dependent protein degradation. The addition of ubiquitin to proteins being degraded is performed by a reaction cascade consisting of three enzymes, named E1 (ubiquitin activating enzyme), E2 (ubiquitin conjugating enzyme), and E3 (ubiquitin ligase). Each E3 has specificity to its substrate, or proteins to be targeted by ubiquitination. Many E3s are discovered in eukaryotes and they are classified into four types: HECT type, U-box type, single RING-finger type, and multi-subunit RING-finger type. Multi-subunit RING-finger E3s are exemplified by cullin-Rbx E3s and APC/C. They consist of a RING-finger-containing subunit (RBX1 or RBX2) that functions to bind E2s, a scaffold-like cullin molecule, adaptor proteins, and a target recognizing subunit that binds substrates.
More...
|
Genes shared at least 5 GO terms with FBXO4 (count: 12)
Genes shared at least 2 KEGG pathways with FBXO4 (count: 0)
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