ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0006511
Name ubiquitin-dependent protein catabolic process
Type biological process
No. of Genes in ADHDgene  31
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 31)

Literature-origin genes (count: 3)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
USP24 ubiquitin specific peptidase 24 1p32.3 1(1/0/0) IEA
PARK2 parkin RBR E3 ubiquitin protein ligase 6q25.2-q27 1(1/0/0) IDA
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) 8q13.3 1(0/0/1) IEA

Genes from other sources Help (count: 28)

Approved Symbol Approved Name Source Evidence[PMID]
FBXO4 F-box protein 4 Mapped by significant region IDA[16275645]
UFD1L ubiquitin fusion degradation 1 like (yeast) Mapped by CNV TAS[9063746]
ANAPC4 anaphase promoting complex subunit 4 Mapped by CNV TAS[9469815]
UBE3A ubiquitin protein ligase E3A Mapped by CNV; Mapped by significant region TAS[8221889]
USP49 ubiquitin specific peptidase 49 Mapped by CNV IEA
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) Mapped by significant region IEA
USP46 ubiquitin specific peptidase 46 Mapped by CNV IEA
USP35 ubiquitin specific peptidase 35 Mapped by significant region IEA
UBA6 ubiquitin-like modifier activating enzyme 6 Mapped by significant region IMP[17889673]
USP34 ubiquitin specific peptidase 34 Mapped by LD-proxy IEA
UBE2I ubiquitin-conjugating enzyme E2I Mapped by significant region TAS[8565643]
FBXO7 F-box protein 7 Mapped by LD-proxy TAS[10531035]
RNF20 ring finger protein 20, E3 ubiquitin protein ligase Mapped by significant region IMP[19037095]
USP22 ubiquitin specific peptidase 22 Mapped by significant region IEA
CUL5 cullin 5 Mapped by significant region; Mapped by PBA pathway IEA
UBE2H ubiquitin-conjugating enzyme E2H Mapped by LD-proxy TAS[8132613]
SQSTM1 sequestosome 1 Mapped by CNV TAS[8702753]
RNF40 ring finger protein 40, E3 ubiquitin protein ligase Mapped by CNV ISS
FBXL7 F-box and leucine-rich repeat protein 7 Mapped by significant region NAS[10531035]
USP37 ubiquitin specific peptidase 37 Mapped by significant region IEA
UBE4A ubiquitination factor E4A Mapped by significant region IEA
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase Mapped by significant region IMP[19713937]
USP2 ubiquitin specific peptidase 2 Mapped by significant region IEA
USP31 ubiquitin specific peptidase 31 Mapped by significant region IEA
USP41 ubiquitin specific peptidase 41 Mapped by CNV IEA
NEDD8 neural precursor cell expressed, developmentally down-regulated 8 Mapped by significant region TAS[9353319]
USP10 ubiquitin specific peptidase 10 Mapped by CNV; Mapped by significant region IEA
USP28 ubiquitin specific peptidase 28 Mapped by significant region IEA