ADHDgene Database

Gene Report

Basic Info

Approved Symbol	FBXO25
Symbol Alias	FBX25
Approved Name	F-box protein 25
Previous Name	F-box only protein 25
Location	8p23.3
Position	chr8:356428-421225, +
External Links	HGNC: 13596 Entrez Gene: 26260 Ensembl: ENSG00000147364 UCSC: uc003wox.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Elia[2010]_99	chr8:228574-405401 (NCBI Build 35 (hg17))	176828	8p23.3	Duplication	Maternal

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 7)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0000151	ubiquitin ligase complex	Cellular Component	NAS[10531035]	15
GO:0003779	actin binding	Molecular Function		46
GO:0004842	ubiquitin-protein ligase activity	Molecular Function	NAS[10531035]	52
GO:0019005	SCF ubiquitin ligase complex	Cellular Component		4
GO:0016567	protein ubiquitination	Biological Process	NAS[10531035]	41
GO:0005634	nucleus	Cellular Component		770
GO:0005515	protein binding	Molecular Function		910

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with FBXO25 (count: 5)

Gene Symbol	Pathway Count	Pathway List
BARD1	5	ubiquitin ligase complex; ubiquitin-protein ligase activity; protein ubiquitination; nucleus; protein binding;
FBXO4	5	ubiquitin ligase complex; ubiquitin-protein ligase activity; SCF ubiquitin ligase complex; protein ubiquitination; protein binding;
RCHY1	5	ubiquitin ligase complex; ubiquitin-protein ligase activity; protein ubiquitination; nucleus; protein binding;
WWP1	5	ubiquitin ligase complex; ubiquitin-protein ligase activity; protein ubiquitination; nucleus; protein binding;
KLHL20	5	actin binding; ubiquitin-protein ligase activity; protein ubiquitination; nucleus; protein binding;

Genes shared at least 2 KEGG pathways with FBXO25 (count: 0)

View in gBrowse

Region: chr8:356428..421225 View in gBrowse