ADHDgene Database

Gene Report

Basic Info

Approved Symbol	FBXO25
Symbol Alias	FBX25
Approved Name	F-box protein 25
Previous Name	"F-box only protein 25"
Location	8p23.3
Position	chr8:356428-421225, 1
External Links	HGNC: 13596 Entrez Gene: 26260 Ensembl: ENSG00000147364 UCSC: uc003wox.3
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Elia[2010]_99	chr8:228574-405401 (NCBI Build 35 (hg17))	176828	8p23.3	Duplication	Maternal

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 7)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0019005	SCF ubiquitin ligase complex	cellular component	ISS	6
GO:0016567	protein ubiquitination	biological process	ISS; NAS[10531035]	48
GO:0005515	protein binding	molecular function	IPI	1015
GO:0000151	ubiquitin ligase complex	cellular component	NAS[10531035]	17
GO:0003779	actin binding	molecular function	IEA	48
GO:0004842	ubiquitin-protein ligase activity	molecular function	NAS[10531035]	60
GO:0005634	nucleus	cellular component	ISS	877

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with FBXO25 (count: 4)

Gene Symbol	Pathway Count	Pathway List
FBXO4	5	SCF ubiquitin ligase complex; protein ubiquitination; protein binding; ubiquitin ligase complex; ubiquitin-protein ligase activity;
BARD1	5	protein ubiquitination; protein binding; ubiquitin ligase complex; ubiquitin-protein ligase activity; nucleus;
RCHY1	5	protein ubiquitination; protein binding; ubiquitin ligase complex; ubiquitin-protein ligase activity; nucleus;
KLHL20	5	protein ubiquitination; protein binding; actin binding; ubiquitin-protein ligase activity; nucleus;

Genes shared at least 2 KEGG pathways with FBXO25 (count: 0)

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Region: chr8:356428..421225 View in gBrowse