ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0003779
Name actin binding
Type molecular function
No. of Genes in ADHDgene  48
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 48)

Literature-origin genes (count: 4)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
MYO5B myosin VB 18q 1(0/1/0) IEA
MYBPC1 myosin binding protein C, slow type 12q23.2 1(0/1/0) IEA
SSFA2 sperm specific antigen 2 2q32.1 1(0/1/0) IEA
FLNC filamin C, gamma 7q32-q35 1(0/0/1) IEA

Genes from other sources Help (count: 44)

Approved Symbol Approved Name Source Evidence[PMID]
MYH11 myosin, heavy chain 11, smooth muscle Mapped by CNV; Mapped by significant region IEA
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa Mapped by significant region IEA
TMOD1 tropomodulin 1 Mapped by significant region IEA
WASL Wiskott-Aldrich syndrome-like Mapped by CNV IEA
TAGLN transgelin Mapped by significant region IEA
GSN gelsolin Mapped by significant region; Mapped by PBA pathway IEA
MYO19 myosin XIX Mapped by CNV IEA
DIXDC1 DIX domain containing 1 Mapped by significant region IEA
FBXO25 F-box protein 25 Mapped by CNV IEA
FLII flightless I homolog (Drosophila) Mapped by significant region IEA
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa Mapped by significant region IEA
SNTG2 syntrophin, gamma 2 Mapped by CNV IEA
MKL2 MKL/myocardin-like 2 Mapped by significant region IEA
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta Mapped by PBA pathway IEA
MPRIP myosin phosphatase Rho interacting protein Mapped by significant region IEA
FKBP15 FK506 binding protein 15, 133kDa Mapped by significant region IEA
COTL1 coactosin-like 1 (Dictyostelium) Mapped by CNV; Mapped by significant region IDA[11583571]
KLHL20 kelch-like family member 20 Mapped by significant region IEA
KLHL1 kelch-like family member 1 Mapped by CNV NAS[10888605]
EPB41L2 erythrocyte membrane protein band 4.1-like 2 Mapped by significant region IEA
CCDC88A coiled-coil domain containing 88A Mapped by PBA pathway IDA[16139227]
ALDOA aldolase A, fructose-bisphosphate Mapped by CNV TAS[1008835]
SPIRE2 spire-type actin nucleation factor 2 Mapped by significant region IEA
RDX radixin Mapped by significant region IEA
SSH3 slingshot protein phosphatase 3 Mapped by significant region IBA
PLEKHH2 pleckstrin homology domain containing, family H (with MyTH4 domain) member 2 Mapped by CNV ISS
LMOD2 leiomodin 2 (cardiac) Mapped by CNV IEA
CFL1 cofilin 1 (non-muscle) Mapped by significant region IEA
SPIRE1 spire-type actin nucleation factor 1 Mapped by CNV IEA
TPM3P4 tropomyosin 3 pseudogene 4 Mapped by significant region IEA
CAPG capping protein (actin filament), gelsolin-like Mapped by PBA pathway IEA
FHOD3 formin homology 2 domain containing 3 Mapped by significant region IEA
ARPC5L actin related protein 2/3 complex, subunit 5-like Mapped by significant region IEA
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) Mapped by PBA pathway IDA[12421915]
FMN1 formin 1 Mapped by CNV; Mapped by significant region IEA
TNS1 tensin 1 Mapped by significant region IEA
INPPL1 inositol polyphosphate phosphatase-like 1 Mapped by significant region IEA
ACTN3 actinin, alpha 3 (gene/pseudogene) Mapped by significant region IEA
IQGAP2 IQ motif containing GTPase activating protein 2 Mapped by CNV TAS[8756646]
DNASE1 deoxyribonuclease I Mapped by significant region IEA
MYO15A myosin XVA Mapped by significant region IEA
SPTBN2 spectrin, beta, non-erythrocytic 2 Mapped by significant region IEA
MEFV Mediterranean fever Mapped by significant region IDA[11468188]
TMSB4Y thymosin beta 4, Y-linked Mapped by PBA pathway IEA