ADHDgene Database

Gene Report

Basic Info

Approved Symbol	FMN1
Previous Symbol	LD, FMN
Symbol Alias	DKFZP686C2281, FLJ45135, MGC125288, MGC125289
Approved Name	formin 1
Previous Name	"formin (limb deformity)"
Name Alias	"limb deformity protein"
Location	15q13.3
Position	chr15:33057747-33486897, -1
External Links	HGNC: 3768 Entrez Gene: 342184 Ensembl: ENSG00000248905 UCSC: uc031qrh.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV; Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Williams[2010]_44	chr15:30688712-32587887 (NCBI Build 36.1 (hg18))	1871368	15q13.3-15q14	Gain	Maternal

Gene related other variant (count: 0)

Gene related regions (count: 2)

Region Name	Position	No. of Studies (significant/non-significant/trend)
15q11.2-13.3	chr15:20700000-33600000	1 (1/0/0)
15q13.3	chr15:31200000-33600000	1 (1/0/0)

Gene related GO terms (count: 15)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0035136	forelimb morphogenesis	biological process	IEA	5
GO:0048705	skeletal system morphogenesis	biological process	IEA	4
GO:0035137	hindlimb morphogenesis	biological process	IEA	3
GO:0005634	nucleus	cellular component	IEA	877
GO:0017124	SH3 domain binding	molecular function	IEA	22
GO:0005912	adherens junction	cellular component	IEA	9
GO:0010467	gene expression	biological process	IEA	154
GO:0003779	actin binding	molecular function	IEA	48
GO:0015629	actin cytoskeleton	cellular component	IEA	30
GO:0005886	plasma membrane	cellular component	IEA	839
GO:0005737	cytoplasm	cellular component	IEA	781
GO:0030838	positive regulation of actin filament polymerization	biological process	IEA	10
GO:0051127	positive regulation of actin nucleation	biological process	IEA	1
GO:0030036	actin cytoskeleton organization	biological process	IEA	23
GO:0003677	DNA binding	molecular function	IEA	257

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with FMN1 (count: 3)

Gene Symbol	Pathway Count	Pathway List
NF2	5	nucleus; adherens junction; plasma membrane; cytoplasm; actin cytoskeleton organization;
BAIAP2	5	nucleus; SH3 domain binding; actin cytoskeleton; plasma membrane; cytoplasm;
ARPC2	5	actin binding; actin cytoskeleton; plasma membrane; cytoplasm; positive regulation of actin filament polymerization;

Genes shared at least 2 KEGG pathways with FMN1 (count: 0)

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Region: chr15:33057747..33486897 View in gBrowse