Gene Report
Basic Info
Approved Symbol |
GSN
|
Symbol Alias |
DKFZp313L0718 |
Approved Name |
gelsolin |
Previous Name |
gelsolin (amyloidosis, Finnish type) |
Name Alias |
amyloidosis, Finnish type |
Location |
9q33 |
Position |
chr9:123970075-124095121, + |
External Links |
HGNC: 4620
Entrez Gene: 2934
Ensembl: ENSG00000148180
UCSC: uc004blf.1
|
No. of Studies |
0 (significant: 0; non-significant: 0; trend: 0) |
Source |
Mapped by PBA pathway; Mapped by significant region |
Gene related studies (count: 0)
Gene related SNPs (count: 0)
Gene related CNVs (count: 0)
Gene related other variant (count: 0)
Gene related regions (count: 1)
Gene related GO terms (count: 28)
Gene related KEGG pathways (count: 2)
ID |
Name |
No. of Genes in ADHDgene |
Brief Description |
hsa04666 |
Fc gamma R-mediated phagocytosis |
28 |
Phagocytosis plays an essential role in host-defense mechani......
Phagocytosis plays an essential role in host-defense mechanisms through the uptake and destruction of infectious pathogens. Specialized cell types including macrophages, neutrophils, and monocytes take part in this process in higher organisms. After opsonization with antibodies (IgG), foreign extracellular materials are recognized by Fc gamma receptors. Cross-linking of Fc gamma receptors initiates a variety of signals mediated by tyrosine phosphorylation of multiple proteins, which lead through the actin cytoskeleton rearrangements and membrane remodeling to the formation of phagosomes. Nascent phagosomes undergo a process of maturation that involves fusion with lysosomes. The acquisition of lysosomal proteases and release of reactive oxygen species are crucial for digestion of engulfed materials in phagosomes.
More...
|
hsa04810 |
Regulation of actin cytoskeleton |
48 |
|
Genes shared at least 5 GO terms with GSN (count: 13)
Genes shared at least 2 KEGG pathways with GSN (count: 11)
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