ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

KEGG Pathway Report

Basic Info
ID hsa04810
Name Regulation of actin cytoskeleton
No. of Genes in ADHDgene  49
Source Pathway by Database Search

Pathway related genes in ADHDgene (count: 49)

Literature-origin genes (count: 8)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend)
FGF12 fibroblast growth factor 12 3q28 1(0/1/0)
TIAM2 T-cell lymphoma invasion and metastasis 2 6q25 1(0/0/1)
FGF10 fibroblast growth factor 10 5p13-p12 1(0/1/0)
ITGA11 integrin, alpha 11 15q22.3-q23 1(0/0/1)
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 17p13 1(0/0/1)
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 17p11.2 2(1/1/0)
ITGA1 integrin, alpha 1 5q11.1 2(0/2/0)
BAIAP2 BAI1-associated protein 2 17q25 1(1/0/0)

Genes from other sources Help(count: 41)

Approved Symbol Approved Name Location Source
CFL1 cofilin 1 (non-muscle) 11q13.1 Mapped by significant region
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 11q23.3 Mapped by significant region
WASL Wiskott-Aldrich syndrome-like 7q31.3 Mapped by CNV
ARPC5L actin related protein 2/3 complex, subunit 5-like 9q34.11 Mapped by significant region
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle 16p11.2 Mapped by CNV
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 2p24 Mapped by significant region
FGF4 fibroblast growth factor 4 11q13.3 Mapped by significant region
BCAR1 breast cancer anti-estrogen resistance 1 16q22-q23 Mapped by significant region
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 5q13.1 Mapped by significant region
FGF9 fibroblast growth factor 9 13q11-q12 Mapped by significant region
RDX radixin 11q23 Mapped by significant region
FGF3 fibroblast growth factor 3 11q13 Mapped by significant region
IQGAP2 IQ motif containing GTPase activating protein 2 5q Mapped by CNV
FGD3 FYVE, RhoGEF and PH domain containing 3 9q22 Mapped by significant region
APC adenomatous polyposis coli 5q21-q22 Mapped by LD-proxy; Mapped by PBA pathway
SSH3 slingshot protein phosphatase 3 11q13 Mapped by significant region
CHRM1 cholinergic receptor, muscarinic 1 11q12-q13 Mapped by significant region; Mapped by PBA pathway
INS insulin 11p15.5 Mapped by Literature SNP
PPP1R12B protein phosphatase 1, regulatory subunit 12B 1q32.1 Mapped by Literature SNP
MAPK3 mitogen-activated protein kinase 3 16p11.2 Mapped by CNV
CHRM3 cholinergic receptor, muscarinic 3 1q43 Mapped by CNV; Mapped by PBA pathway
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 2q36.1 Mapped by significant region
GSN gelsolin 9q33 Mapped by significant region; Mapped by PBA pathway
CYFIP1 cytoplasmic FMR1 interacting protein 1 15q11 Mapped by significant region
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 5q11.2 Mapped by LD-proxy
CHRM5 cholinergic receptor, muscarinic 5 15q26 Mapped by CNV; Mapped by PBA pathway
FN1 fibronectin 1 2q34 Mapped by significant region
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4 2q22 Mapped by CNV; Mapped by significant region
PAK7 p21 protein (Cdc42/Rac)-activated kinase 7 20p12 Mapped by CNV
TMSB4Y thymosin beta 4, Y-linked Yq11.221 Mapped by PBA pathway
MAPK1 mitogen-activated protein kinase 1 22q11.2 Mapped by LD-proxy
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like 22q11.21 Mapped by CNV
ACTN3 actinin, alpha 3 (gene/pseudogene) 11q13.2 Mapped by significant region
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 16p13.1-p11 Mapped by CNV
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 7q22 Mapped by CNV
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 1q Mapped by significant region
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 11q13-q14 Mapped by significant region
CYFIP2 cytoplasmic FMR1 interacting protein 2 5q34 Mapped by significant region
BDKRB2 bradykinin receptor B2 14q32.1-q32.2 Mapped by PBA pathway
FGF19 fibroblast growth factor 19 11q13.1 Mapped by significant region
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 11q13 Mapped by significant region