ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0015629
Name actin cytoskeleton
Type cellular component
No. of Genes in ADHDgene  30
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 30)

Literature-origin genes (count: 4)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
SNCA synuclein, alpha (non A4 component of amyloid precursor) 4q21.3-q22 1(0/1/0) IDA[17408955]
CTNNA2 catenin (cadherin-associated protein), alpha 2 2p12-p11.1 2(1/1/0) IEA
BAIAP2 BAI1-associated protein 2 17q25 1(1/0/0) IDA[19366662]
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) 7p22 1(0/1/0) IDA

Genes from other sources Help (count: 26)

Approved Symbol Approved Name Source Evidence[PMID]
LIMA1 LIM domain and actin binding 1 Mapped by PBA pathway IDA
CORO2A coronin, actin binding protein, 2A Mapped by significant region IBA
FYB FYN binding protein Mapped by significant region TAS[10747096]
ALDOA aldolase A, fructose-bisphosphate Mapped by CNV IDA[9244396]
ADAM17 ADAM metallopeptidase domain 17 Mapped by significant region IDA[17010968]
COPB2 coatomer protein complex, subunit beta 2 (beta prime) Mapped by PBA pathway IDA
CORO1B coronin, actin binding protein, 1B Mapped by significant region IBA
TARS threonyl-tRNA synthetase Mapped by significant region IDA
IQGAP2 IQ motif containing GTPase activating protein 2 Mapped by CNV TAS[8756646]
PPP1R12B protein phosphatase 1, regulatory subunit 12B Mapped by Literature SNP IDA
ARHGAP32 Rho GTPase activating protein 32 Mapped by significant region IEA
GSN gelsolin Mapped by significant region; Mapped by PBA pathway IEA
ZNF74 zinc finger protein 74 Mapped by CNV IDA
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) Mapped by CNV IDA
CORO7 coronin 7 Mapped by significant region IRD
KLHL20 kelch-like family member 20 Mapped by significant region TAS[10888605]
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa Mapped by significant region TAS[9230079]
PKNOX2 PBX/knotted 1 homeobox 2 Mapped by significant region IEA
ZNF174 zinc finger protein 174 Mapped by significant region IDA
C10orf90 chromosome 10 open reading frame 90 Mapped by CNV IDA
FMN1 formin 1 Mapped by CNV; Mapped by significant region IEA
CTNNA3 catenin (cadherin-associated protein), alpha 3 Mapped by CNV IEA
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 Mapped by significant region IEA
WASL Wiskott-Aldrich syndrome-like Mapped by CNV TAS[9422512]
ACTL7B actin-like 7B Mapped by significant region TAS[10373328]
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa Mapped by significant region TAS[9230079]