ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	ARHGAP32
Symbol Alias	GRIT, KIAA0712, MGC1892, RICS, GC-GAP
Approved Name	Rho GTPase activating protein 32
Location	11q24.3
Position	chr11:128834955-129149219, -
External Links	HGNC: 17399 Entrez Gene: 9743 Ensembl: ENSG00000134909
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)

Gene related GO terms (count: 15)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 15)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0030054	cell junction	Cellular Component		77
GO:0035091	phosphatidylinositol binding	Molecular Function		13
GO:0014069	postsynaptic density	Cellular Component		23
GO:0015629	actin cytoskeleton	Cellular Component		26
GO:0045211	postsynaptic membrane	Cellular Component		41
GO:0051056	regulation of small GTPase mediated signal transduction	Biological Process		30
GO:0005789	endoplasmic reticulum membrane	Cellular Component		140
GO:0005829	cytosol	Cellular Component		447
GO:0005096	GTPase activator activity	Molecular Function		23
GO:0005515	protein binding	Molecular Function	IPI[12788081]	910
GO:0007264	small GTPase mediated signal transduction	Biological Process		58
GO:0010008	endosome membrane	Cellular Component		27
GO:0005886	plasma membrane	Cellular Component		772
GO:0005938	cell cortex	Cellular Component		26
GO:0000139	Golgi membrane	Cellular Component		95

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with ARHGAP32 (count: 15)

Gene Symbol	Pathway Count	Pathway List
GOPC	6	cell junction; postsynaptic density; postsynaptic membrane; protein binding; plasma membrane; Golgi membrane;
SNCA	6	cell junction; actin cytoskeleton; cytosol; protein binding; plasma membrane; cell cortex;
BAIAP2	5	cell junction; actin cytoskeleton; cytosol; protein binding; plasma membrane;
CNIH2	5	cell junction; postsynaptic density; postsynaptic membrane; endoplasmic reticulum membrane; protein binding;
DLG2	5	cell junction; postsynaptic density; postsynaptic membrane; protein binding; plasma membrane;
GRIN2A	5	cell junction; postsynaptic density; postsynaptic membrane; protein binding; plasma membrane;
GRIN2B	5	cell junction; postsynaptic density; postsynaptic membrane; protein binding; plasma membrane;
SHANK2	5	cell junction; postsynaptic density; postsynaptic membrane; protein binding; plasma membrane;
PLD2	5	phosphatidylinositol binding; endoplasmic reticulum membrane; protein binding; small GTPase mediated signal transduction; plasma membrane;
ARRB2	5	postsynaptic density; postsynaptic membrane; cytosol; protein binding; plasma membrane;
ARAP1	5	regulation of small GTPase mediated signal transduction; cytosol; protein binding; small GTPase mediated signal transduction; plasma membrane;
ARHGEF12	5	regulation of small GTPase mediated signal transduction; cytosol; GTPase activator activity; protein binding; small GTPase mediated signal transduction;
ARRB1	5	cytosol; GTPase activator activity; protein binding; plasma membrane; Golgi membrane;
RAB14	5	cytosol; protein binding; small GTPase mediated signal transduction; plasma membrane; Golgi membrane;
ARF6	5	protein binding; small GTPase mediated signal transduction; endosome membrane; plasma membrane; cell cortex;

Genes shared at least 2 KEGG pathways with ARHGAP32 (count: 0)

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Region: chr11:128834955..129149219 View in gBrowse