ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	ARHGAP32
Symbol Alias	GRIT, KIAA0712, MGC1892, RICS, GC-GAP
Approved Name	Rho GTPase activating protein 32
Location	11q24.3
Position	chr11:128834955-129149219, -1
External Links	HGNC: 17399 Entrez Gene: 9743 Ensembl: ENSG00000134909 UCSC: uc009zcp.3
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)

Gene related GO terms (count: 15)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 15)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0000139	Golgi membrane	cellular component	IEA	106
GO:0005096	GTPase activator activity	molecular function	IEA	28
GO:0005789	endoplasmic reticulum membrane	cellular component	IEA	159
GO:0007264	small GTPase mediated signal transduction	biological process	TAS	65
GO:0045211	postsynaptic membrane	cellular component	IEA	45
GO:0005938	cell cortex	cellular component	IEA	29
GO:0051056	regulation of small GTPase mediated signal transduction	biological process	TAS	32
GO:0030054	cell junction	cellular component	IEA	84
GO:0014069	postsynaptic density	cellular component	IEA	26
GO:0035091	phosphatidylinositol binding	molecular function	IEA	17
GO:0005886	plasma membrane	cellular component	IEA	839
GO:0010008	endosome membrane	cellular component	IEA	31
GO:0005515	protein binding	molecular function	IPI[12788081]	1015
GO:0005829	cytosol	cellular component	TAS	485
GO:0015629	actin cytoskeleton	cellular component	IEA	30

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with ARHGAP32 (count: 19)

Gene Symbol	Pathway Count	Pathway List
GOPC	6	Golgi membrane; postsynaptic membrane; cell junction; postsynaptic density; plasma membrane; protein binding;
AXIN1	6	GTPase activator activity; cell cortex; postsynaptic density; plasma membrane; protein binding; cytosol;
SNCA	6	cell cortex; cell junction; plasma membrane; protein binding; cytosol; actin cytoskeleton;
ARRB1	5	Golgi membrane; GTPase activator activity; plasma membrane; protein binding; cytosol;
RAB14	5	Golgi membrane; small GTPase mediated signal transduction; plasma membrane; protein binding; cytosol;
ARHGEF12	5	GTPase activator activity; small GTPase mediated signal transduction; regulation of small GTPase mediated signal transduction; protein binding; cytosol;
CNIH2	5	endoplasmic reticulum membrane; postsynaptic membrane; cell junction; postsynaptic density; protein binding;
PLD2	5	endoplasmic reticulum membrane; small GTPase mediated signal transduction; phosphatidylinositol binding; plasma membrane; protein binding;
ARF6	5	small GTPase mediated signal transduction; cell cortex; plasma membrane; endosome membrane; protein binding;
DNAJA3	5	small GTPase mediated signal transduction; postsynaptic membrane; cell junction; protein binding; cytosol;
ARAP1	5	small GTPase mediated signal transduction; regulation of small GTPase mediated signal transduction; plasma membrane; protein binding; cytosol;
RHOT2	5	small GTPase mediated signal transduction; regulation of small GTPase mediated signal transduction; plasma membrane; protein binding; cytosol;
DISC1	5	postsynaptic membrane; cell junction; postsynaptic density; plasma membrane; protein binding;
ARRB2	5	postsynaptic membrane; postsynaptic density; plasma membrane; protein binding; cytosol;
GRIN2A	5	postsynaptic membrane; cell junction; postsynaptic density; plasma membrane; protein binding;
DLG2	5	postsynaptic membrane; cell junction; postsynaptic density; plasma membrane; protein binding;
GRIN2B	5	postsynaptic membrane; cell junction; postsynaptic density; plasma membrane; protein binding;
SHANK2	5	postsynaptic membrane; cell junction; postsynaptic density; plasma membrane; protein binding;
BAIAP2	5	cell junction; plasma membrane; protein binding; cytosol; actin cytoskeleton;

Genes shared at least 2 KEGG pathways with ARHGAP32 (count: 0)

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Region: chr11:128834955..129149219 View in gBrowse