ADHDgene Database

Gene Report

Basic Info

Approved Symbol	TARS
Approved Name	threonyl-tRNA synthetase
Name Alias	threonine tRNA ligase 1, cytoplasmic
Location	5p13.2
Position	chr5:33440802-33469644, +
External Links	HGNC: 11572 Entrez Gene: 6897 Ensembl: ENSG00000113407 UCSC: uc003jhy.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
5p13	chr5:28900000-42500000	3 (1/1/1)

Gene related GO terms (count: 10)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005829	cytosol	Cellular Component		447
GO:0006412	translation	Biological Process	NAS[2033077]	42
GO:0005524	ATP binding	Molecular Function		228
GO:0005737	cytoplasm	Cellular Component	NAS[2033077]	690
GO:0004829	threonine-tRNA ligase activity	Molecular Function	NAS[2033077]	2
GO:0042803	protein homodimerization activity	Molecular Function	NAS[2033077]	113
GO:0006435	threonyl-tRNA aminoacylation	Biological Process	NAS[2033077]	2
GO:0006418	tRNA aminoacylation for protein translation	Biological Process		8
GO:0015629	actin cytoskeleton	Cellular Component		26
GO:0010467	gene expression	Biological Process		140

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa00970	Aminoacyl-tRNA biosynthesis	10

Genes shared at least 5 GO terms with TARS (count: 4)

Gene Symbol	Pathway Count	Pathway List
SARS	6	cytosol; translation; ATP binding; cytoplasm; tRNA aminoacylation for protein translation; gene expression;
IARS	5	cytosol; ATP binding; cytoplasm; tRNA aminoacylation for protein translation; gene expression;
KARS	5	cytosol; ATP binding; cytoplasm; tRNA aminoacylation for protein translation; gene expression;
NARS	5	cytosol; ATP binding; cytoplasm; tRNA aminoacylation for protein translation; gene expression;

Genes shared at least 2 KEGG pathways with TARS (count: 0)

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Region: chr5:33440802..33469644 View in gBrowse