ADHDgene Database

Gene Report

Basic Info

Approved Symbol	SARS
Symbol Alias	SERS
Approved Name	seryl-tRNA synthetase
Name Alias	serine tRNA ligase 1, cytoplasmic
Location	1p13.3
Position	chr1:109756515-109780804, +
External Links	HGNC: 10537 Entrez Gene: 6301 Ensembl: ENSG00000031698 UCSC: uc001dwu.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Jarick[2012]_1	chr1:109103606-109682244 (NCBI36 / hg18)	578639	1p13.3	dup

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 12)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0006418	tRNA aminoacylation for protein translation	Biological Process		8
GO:0006434	seryl-tRNA aminoacylation	Biological Process		1
GO:0008033	tRNA processing	Biological Process	TAS[9431993]	11
GO:0010467	gene expression	Biological Process		140
GO:0005737	cytoplasm	Cellular Component		690
GO:0005739	mitochondrion	Cellular Component		183
GO:0005829	cytosol	Cellular Component		447
GO:0006412	translation	Biological Process	TAS[9431993]	42
GO:0003723	RNA binding	Molecular Function	TAS[9431993]	104
GO:0005524	ATP binding	Molecular Function		228
GO:0004828	serine-tRNA ligase activity	Molecular Function		1
GO:0097056	selenocysteinyl-tRNA(Sec) biosynthetic process	Biological Process		2

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa00970	Aminoacyl-tRNA biosynthesis	10

Genes shared at least 5 GO terms with SARS (count: 9)

Gene Symbol	Pathway Count	Pathway List
KARS	7	tRNA aminoacylation for protein translation; tRNA processing; gene expression; cytoplasm; mitochondrion; cytosol; ATP binding;
NARS	6	tRNA aminoacylation for protein translation; gene expression; cytoplasm; mitochondrion; cytosol; ATP binding;
TARS	6	tRNA aminoacylation for protein translation; gene expression; cytoplasm; cytosol; translation; ATP binding;
RPS15A	6	gene expression; cytoplasm; mitochondrion; cytosol; translation; RNA binding;
EARS2	5	tRNA aminoacylation for protein translation; gene expression; mitochondrion; RNA binding; ATP binding;
IARS	5	tRNA aminoacylation for protein translation; gene expression; cytoplasm; cytosol; ATP binding;
RPL14	5	gene expression; cytoplasm; cytosol; translation; RNA binding;
RPS25	5	gene expression; cytoplasm; cytosol; translation; RNA binding;
SRP19	5	gene expression; cytoplasm; mitochondrion; cytosol; translation;

Genes shared at least 2 KEGG pathways with SARS (count: 0)

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Region: chr1:109756515..109780804 View in gBrowse