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- Data Summary
GO Report
Basic Info
| ID | GO:0007568 |
|---|---|
| Name | aging |
| Type | biological process |
| No. of Genes in ADHDgene | 29 |
| Source | Pathway by Database Search |
PBA Result (with statistical significance of FDR<0.05)
GO related genes in ADHDgene (count: 29)
Literature-origin genes (count: 11)
| Approved Symbol | Approved Name | Location | No. of Studies (significant/non-significant/trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| CNR1 | cannabinoid receptor 1 (brain) | 6q14-q15 | 1(1/0/0) | IEA |
| FADS1 | fatty acid desaturase 1 | 11q12-q13.1 | 3(1/2/0) | IEA |
| HTR2A | 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled | 13q14-q21 | 13(7/6/0) | IEA |
| SLC6A3 | solute carrier family 6 (neurotransmitter transporter), member 3 | 5p15.3 | 70(43/26/1) | IEA |
| ADRA1A | adrenoceptor alpha 1A | 8p21.2 | 3(2/1/0) | ISS |
| ADRB1 | adrenoceptor beta 1 | 10q25.3 | 2(0/2/0) | IEA |
| ADRB3 | adrenoceptor beta 3 | 8p12 | 2(0/2/0) | IEA |
| SLC18A2 | solute carrier family 18 (vesicular monoamine transporter), member 2 | 10q25 | 2(0/2/0) | IEA |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 9q22.1 | 1(1/0/0) | IEA |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 4q21.3-q22 | 1(0/1/0) | IEA |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O | 16q13 | 1(0/1/0) | IEA |
Genes from other sources (count: 18)
| Approved Symbol | Approved Name | Source | Evidence[PMID] |
|---|---|---|---|
| IREB2 | iron-responsive element binding protein 2 | Mapped by LD-proxy | IEA |
| UCP3 | uncoupling protein 3 (mitochondrial, proton carrier) | Mapped by CNV; Mapped by significant region | IEA |
| SREBF1 | sterol regulatory element binding transcription factor 1 | Mapped by significant region | IEA |
| NCF2 | neutrophil cytosolic factor 2 | Mapped by significant region | IEA |
| CACYBP | calcyclin binding protein | Mapped by significant region | IEA |
| PDE4D | phosphodiesterase 4D, cAMP-specific | Mapped by CNV | IEA |
| RELA | v-rel avian reticuloendotheliosis viral oncogene homolog A | Mapped by significant region | IEA |
| GSN | gelsolin | Mapped by significant region; Mapped by PBA pathway | IEA |
| EDNRA | endothelin receptor type A | Mapped by PBA pathway | IEA |
| TACR3 | tachykinin receptor 3 | Mapped by CNV | IEA |
| FOXG1 | forkhead box G1 | Mapped by significant region | IEA |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | Mapped by significant region | IEA |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | Mapped by significant region | IEA |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate contransporter), member 2 | Mapped by CNV | IEA |
| CTSC | cathepsin C | Mapped by significant region | IEA |
| CANX | calnexin | Mapped by CNV | IEA |
| IL6 | interleukin 6 (interferon, beta 2) | Mapped by significant region | IEA |
| CRYAB | crystallin, alpha B | Mapped by significant region | IEA |