ADHDgene Database

Gene Report

Basic Info

Approved Symbol	MYO5B
Symbol Alias	KIAA1119
Approved Name	myosin VB
Location	18q
Position	chr18:47349101-47721451, -
External Links	HGNC: 7603 Entrez Gene: 4645 Ensembl: ENSG00000167306 UCSC: uc002leb.2
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin; Mapped by CNV; Mapped by LD-proxy; Mapped by literature SNP

Gene related studies (count: 1)

Reference	Statistical Values/Author Comments	Result of Statistical Analysis
Landaas ET, 2011	no SNP showed evidence of association	Non-significant

Gene related SNPs (count: 5)

rs_ID	Location	Functional Annotation	No. of Studies (significant/non-significant/trend)
rs4939921	Chr18:47462328(Fwd)	intron_variant	1(0/1/0)

rs_ID	Location	Functional Annotation
rs11660745	Chr18:47443440(Fwd)	intron_variant
rs2298624	Chr18:47429022(Fwd)	missense_variant
rs1942419	Chr18:47377751(Fwd)	downstream_gene_variant; intron_variant; upstream_gene_variant
rs17801369	Chr18:47479491(Fwd)	intron_variant

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Elia[2010]_195	chr18:45713229-45928259 (NCBI Build 35 (hg17))	215031	18q21.1	Duplication	Maternal

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 13)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0055085	transmembrane transport	Biological Process		82
GO:0043234	protein complex	Cellular Component	IDA[17462998]	45
GO:0030659	cytoplasmic vesicle membrane	Cellular Component		18
GO:0017137	Rab GTPase binding	Molecular Function	IPI[17462998]	8
GO:0016459	myosin complex	Cellular Component		4
GO:0016192	vesicle-mediated transport	Biological Process	IMP[17462998]	28
GO:0015031	protein transport	Biological Process		75
GO:0006833	water transport	Biological Process		6
GO:0005524	ATP binding	Molecular Function		228
GO:0005516	calmodulin binding	Molecular Function		32
GO:0005515	protein binding	Molecular Function	IPI[19542231]	910
GO:0003779	actin binding	Molecular Function		46
GO:0000146	microfilament motor activity	Molecular Function		2

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with MYO5B (count: 1)

Gene Symbol	Pathway Count	Pathway List
MYO7A	5	myosin complex; ATP binding; calmodulin binding; protein binding; microfilament motor activity;

Genes shared at least 2 KEGG pathways with MYO5B (count: 0)

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Region: chr18:47349101..47721451 View in gBrowse