ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0005516
Name calmodulin binding
Type molecular function
No. of Genes in ADHDgene  33
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 33)

Literature-origin genes (count: 6)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3 Xq28 1(0/1/0) IEA
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 12p13.3 3(0/3/0) IPI[15140941]
CAMK1D calcium/calmodulin-dependent protein kinase ID 10p13 1(0/0/1) IEA
NOS1 nitric oxide synthase 1 (neuronal) 12q24.22 1(1/0/0) IEA
SYT1 synaptotagmin I 12q21.2 4(2/2/0) IEA
MYO5B myosin VB 18q 1(0/1/0) IEA

Genes from other sources Help (count: 27)

Approved Symbol Approved Name Source Evidence[PMID]
RYR2 ryanodine receptor 2 (cardiac) Mapped by CNV; Mapped by PBA pathway IMP[19220289]; IPI; ISS
RIT2 Ras-like without CAAX 2 Mapped by significant region IEA
MYO15A myosin XVA Mapped by significant region IEA
MYO10 myosin X Mapped by significant region IEA
RYR1 ryanodine receptor 1 (skeletal) Mapped by PBA pathway ISS
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) Mapped by PBA pathway IEA
EEF2K eukaryotic elongation factor-2 kinase Mapped by CNV; Mapped by significant region IDA[9144159]
PHKG2 phosphorylase kinase, gamma 2 (testis) Mapped by CNV IEA
CDK5RAP2 CDK5 regulatory subunit associated protein 2 Mapped by significant region IPI
INVS inversin Mapped by significant region IEA
SMTNL1 smoothelin-like 1 Mapped by significant region IEA
TRPV6 transient receptor potential cation channel, subfamily V, member 6 Mapped by PBA pathway IDA[11278579]
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) Mapped by significant region IPI[12821674]
RGS16 regulator of G-protein signaling 16 Mapped by significant region TAS[10747990]
KCNN2 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2 Mapped by LD-proxy IEA
MAP6 microtubule-associated protein 6 Mapped by significant region IEA
STRN3 striatin, calmodulin binding protein 3 Mapped by significant region NAS[10748158]
MYO7A myosin VIIA Mapped by significant region IMP[15300860]
TRPV5 transient receptor potential cation channel, subfamily V, member 5 Mapped by PBA pathway IEA
IQGAP2 IQ motif containing GTPase activating protein 2 Mapped by CNV IEA
NRGN neurogranin (protein kinase C substrate, RC3) Mapped by significant region IEA
RYR3 ryanodine receptor 3 Mapped by CNV; Mapped by PBA pathway IEA
CAMK2D calcium/calmodulin-dependent protein kinase II delta Mapped by CNV IEA
ADCY3 adenylate cyclase 3 Mapped by LD-proxy IEA
MYH11 myosin, heavy chain 11, smooth muscle Mapped by CNV; Mapped by significant region IEA
TRPV1 transient receptor potential cation channel, subfamily V, member 1 Mapped by PBA pathway IEA
TJP1 tight junction protein 1 Mapped by CNV; Mapped by significant region IEA