ADHDgene Database

Hot Results

Quick Search

Keyword:
Type:

Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	MYO7A
Previous Symbol	USH1B, DFNB2, DFNA11
Symbol Alias	NSRD2
Approved Name	myosin VIIA
Previous Name	"myosin VIIA (Usher syndrome 1B (autosomal recessive, severe))"
Location	11q13.5
Position	chr11:76839310-76926284, 1
External Links	HGNC: 7606 Entrez Gene: 4647 Ensembl: ENSG00000137474 UCSC: uc001oyb.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)

Gene related GO terms (count: 30)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 30)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0019904	protein domain specific binding	molecular function	IEA	43
GO:0046983	protein dimerization activity	molecular function	RCA[8622919]	28
GO:0001845	phagolysosome assembly	biological process	IEA	2
GO:0016459	myosin complex	cellular component	IEA	5
GO:0050953	sensory perception of light stimulus	biological process	IMP[11398101]	3
GO:0001750	photoreceptor outer segment	cellular component	IDA[8842737]	7
GO:0007040	lysosome organization	biological process	IDA[16001398]	9
GO:0032420	stereocilium	cellular component	IEA	7
GO:0050957	equilibrioception	biological process	IMP[7870171]	2
GO:0007601	visual perception	biological process	IMP[7870171]	29
GO:0042462	eye photoreceptor cell development	biological process	IC[8842737]	3
GO:0030048	actin filament-based movement	biological process	IDA	1
GO:0060088	auditory receptor cell stereocilium organization	biological process	IEA	2
GO:0005524	ATP binding	molecular function	IEA	265
GO:0005516	calmodulin binding	molecular function	IMP[15300860]	33
GO:0005829	cytosol	cellular component	IDA[15300860]	485
GO:0006886	intracellular protein transport	biological process	IEA	45
GO:0051015	actin filament binding	molecular function	IDA	16
GO:0016324	apical plasma membrane	cellular component	IEA	52
GO:0001917	photoreceptor inner segment	cellular component	IDA[8842737]	5
GO:0045202	synapse	cellular component	IDA[8842737]	35
GO:0007605	sensory perception of sound	biological process	IMP[11398101]	30
GO:0005765	lysosomal membrane	cellular component	IDA[16001398]	23
GO:0000146	microfilament motor activity	molecular function	IDA	2
GO:0042470	melanosome	cellular component	IEA	22
GO:0051904	pigment granule transport	biological process	IEA	1
GO:0005515	protein binding	molecular function	IPI	1015
GO:0005938	cell cortex	cellular component	IEA	29
GO:0032391	photoreceptor connecting cilium	cellular component	IEA	3
GO:0048563	post-embryonic organ morphogenesis	biological process	IEA	2

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with MYO7A (count: 7)

Gene Symbol	Pathway Count	Pathway List
TH	6	protein domain specific binding; visual perception; eye photoreceptor cell development; cytosol; sensory perception of sound; protein binding;
MYO10	6	myosin complex; ATP binding; calmodulin binding; cytosol; actin filament binding; cell cortex;
RAB27A	5	protein domain specific binding; photoreceptor outer segment; apical plasma membrane; melanosome; protein binding;
MYO15A	5	myosin complex; stereocilium; ATP binding; calmodulin binding; sensory perception of sound;
MYO5B	5	myosin complex; ATP binding; calmodulin binding; microfilament motor activity; protein binding;
CDH23	5	sensory perception of light stimulus; stereocilium; equilibrioception; sensory perception of sound; protein binding;
MYH11	5	ATP binding; calmodulin binding; cytosol; melanosome; protein binding;

Genes shared at least 2 KEGG pathways with MYO7A (count: 0)

View in gBrowse

Region: chr11:76839310..76926284 View in gBrowse