ADHDgene Database

Gene Report

Basic Info

Approved Symbol	SPIRE2
Symbol Alias	spir-2, KIAA1832
Approved Name	spire homolog 2 (Drosophila)
Location	16q24
Position	chr16:89894907-89937727, +
External Links	HGNC: 30623 Entrez Gene: 84501 Ensembl: ENSG00000204991 UCSC: uc002foz.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
16q23.1-24.3	chr16:74100000-90354753	1 (1/0/0)

Gene related GO terms (count: 12)

ID	Name	Type	No. of Genes in ADHDgene
GO:0005856	cytoskeleton	Cellular Component	54
GO:0003779	actin binding	Molecular Function	46
GO:0016192	vesicle-mediated transport	Biological Process	28
GO:0005938	cell cortex	Cellular Component	26
GO:0030659	cytoplasmic vesicle membrane	Cellular Component	18
GO:0030036	actin cytoskeleton organization	Biological Process	21
GO:0036089	cleavage furrow formation	Biological Process	2
GO:0032154	cleavage furrow	Cellular Component	8
GO:0040038	polar body extrusion after meiotic divisions	Biological Process	2
GO:0046907	intracellular transport	Biological Process	6
GO:0051295	establishment of meiotic spindle localization	Biological Process	2
GO:0070649	formin-nucleated actin cable assembly	Biological Process	2

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa04320	Dorso-ventral axis formation	6

Genes shared at least 5 GO terms with SPIRE2 (count: 1)

Gene Symbol	Pathway Count	Pathway List
SPIRE1	12	cytoskeleton; actin binding; vesicle-mediated transport; cell cortex; cytoplasmic vesicle membrane; actin cytoskeleton organization; cleavage furrow formation; cleavage furrow; polar body extrusion after meiotic divisions; intracellular transport; establishment of meiotic spindle localization; formin-nucleated actin cable assembly;

Genes shared at least 2 KEGG pathways with SPIRE2 (count: 0)

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Region: chr16:89894907..89937727 View in gBrowse